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Volumn 60, Issue 5, 2003, Pages 1065-1081

High yield synthesis, separation and structural characterization of new [N+N]-polyazamacrocycles

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DERIVATIVE; DIAMINE DERIVATIVE; IMINE; MACROCYCLIC COMPOUND; PYRIDINE DERIVATIVE;

EID: 0038372588     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/com-02-9693     Document Type: Article
Times cited : (13)

References (23)
  • 10
    • 0037593349 scopus 로고    scopus 로고
    • note
    • The solvent seems to play a decisive role in the exclusive formation of the cyclic products, a finding which still waits for a genuine explanation. First experiments to identify and investigate the factors influencing the cyclization reaction of dialdehydes and diamines are underway. Preliminary results show that the solvent and the structure of the aldehyde and amine are the two main factors influencing the product distribution. More detailed results will be published elsewhere.
  • 12
    • 0037931222 scopus 로고    scopus 로고
    • note
    • Thus, new higher cycles are easily accessible. However, the sensitivity of the imine bond resulted in the re-formation of the thermodynamic mixture equilibrium after separation of the cycles. This problem is not existing when the corresponding amine macrocycles were used.
  • 14
    • 85085717913 scopus 로고    scopus 로고
    • note
    • 1H-NMR spectrum indicates the dominance of 3d' in solution. Complexation experiments, however, give only complexes of 3d (cf. ref. 7).
  • 18
    • 0346348185 scopus 로고    scopus 로고
    • 1H-NMR experiment we obtained spectra with unresolved signal patterns. Additional peaks correspond most probably to imine E/Z isomers of the imine substructures as known in literature [a] J. R. Pliego, A. F. C. Alcântara, D. P. Veloso, and W. B. Almeida, J. Braz. Chem. Soc., 1999, 10, 381.
    • (1999) J. Braz. Chem. Soc. , vol.10 , pp. 381
    • Pliego, J.R.1    Alcântara, A.F.C.2    Veloso, D.P.3    Almeida, W.B.4
  • 19
    • 37049137779 scopus 로고
    • b) J. BjØrgo, D. R. Boyd, Ch. G. Watson, W. B. Jennings, and D. M. Jerina, J. Chem. Soc., Perkin Trans. 2, 1974, 1081]. As the imine macrocycles contain 4 or more imine bonds, different isomers occur, which make it impossible to determine coupling constants etc. This argumentation is supported by the fact that in case of reduced macrocycles (4a,b) nicely resolved spectra are obtained.
    • (1974) J. Chem. Soc., Perkin Trans. 2 , pp. 1081
    • BjØrgo, J.1    Boyd, D.R.2    Watson, Ch.G.3    Jennings, W.B.4    Jerina, D.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.