Surviving hypoxia: The importance of rafts, anchors, and fluidity

Circulation Research

Volumn 92, Issue 8, 2003, Pages 821-823

  Bhatnagar, Aruni ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

Adenosine; Ecto 5 nucleotidase; Endothelium; Hypoxia; Membrane fluidity

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; ECTO 5' NUCLEOTIDASE; PROTEIN KINASE C;

CELL HYPOXIA; CELL MEMBRANE FLUIDITY; EDITORIAL; ENDOCYTOSIS; HUMAN; METABOLIC REGULATION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN MODIFICATION; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM;

5'-NUCLEOTIDASE; ANIMALS; ANOXIA; CELL MEMBRANE; ENDOTHELIUM, VASCULAR; MEMBRANE FLUIDITY; MODELS, BIOLOGICAL; PALMITIC ACID;

EID: 0038370068     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000071524.93731.34     Document Type: Editorial

References (12)

1. Zimmermann H. 5′Nucleotidase: molecular and functional aspects. Biochem J. 1992;285:345-365.
2. Kitakaze M. How to mediate cardioprotection in ischemic hearts: role of adenosine. In: Dhalla NS, Takeda N, Singh M, Lukas A, eds. Myocardial Ischemia and Preconditioning. Dordrecht, the Netherlands: Kluwer Academic Publishers; 2003:293-316.
3. Marshall JM. The integrated response to hypoxia: from circulation to cells. Exp Physiol. 1999;84:449-470.
4. Kloner RA, Jennings RB. Consequences of brief ischemia: stunning, preconditioning, and their clinical implications: part 2. Circulation. 2001;104:3158-3167.
5. Bolli R. The late phase of preconditioning. Circ Res. 2000;87:972-983.
6. Synnertvedt K, Furuta GT, Comerford KM, Louis N, Karhausen J, Eltzschig HK, Hansen KR, Thompson LF, Colgan SP. Ecto-5′-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia. J Clin Invest. 2002;110:993-1002.
7. Ledoux S, Runembert I, Koumanov K, Michel JB, Trugnan G, Friedlander G. Hypoxia enhances Ecto-5′-Nucleotidase activity and cell surface expression in endothelial cells: role of membrane lipids. Circ Res. 2003;92:848-855.
8. Obata T. Adenosine production and its interaction with protection of ischemic and reperfusion injury of the myocardium. Life Sci. 2002;71:2083-2103.
9. Widnell CC, Schneider Y-J, Pierre B, Baudhuin P, Trout A. Evidence for a continual exchange of 5′-nucleotidase between the cell surface and cytoplasmic membranes in cultured rat fibroblasts. Cell. 1982;28:61-709.
10. Mayor S, Sabharanjak S, Maxfield FR. Cholesterol-dependent retention of GPI-anchored proteins in endosomes. EMBO J. 1998;17:4626-4638.
11. Ledoux S, Laouari M, Essig I, Runembert I, Trugnan G, Michel JB, Friedlander G. Lovastatin enhances ecto-5′-nucleotidase activity and cell surface expression in endothelial cells: implications of Rho-family GTPases. Circ Res. 2002;90:420-427.
12. Seta KK, Spicer Y, Yuan Y, Lu G, Millhorn DE. Responding to hypoxia: lessons from a model cell line. Sci STKE. 2002;146:RE11.