Different inhibition mechanisms of dipeptidyl peptidase IV by tryptophan containing peptides and amides

Advances in Experimental Medicine and Biology

Volumn 524, Issue , 2003, Pages 69-72

  Stöckel Maschek, Angela ^a   Stiebitz, Beate ^a   Faust, Jürgen ^a   Born, Ilona ^a   Kähne, Thilo ^b   Gorrell, Mark D ^c   Neubert, Klaus ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

^c ROYAL PRINCE ALFRED HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; DIPEPTIDYL PEPTIDASE IV; PEPTIDE; TRYPTOPHAN;

COMPETITIVE INHIBITION; CONFERENCE PAPER; ENZYME INHIBITION; ENZYME KINETICS; HYDROLYSIS; PRIORITY JOURNAL;

AMIDES; ANIMALS; ANTIGENS, CD; HUMANS; KIDNEY; KINETICS; PEPTIDES; PROTEASE INHIBITORS; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; SWINE; TRYPTOPHAN;

EID: 0038363935     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (5)

1. Fleischer, B. 1995, Molecular Biology Intelligence Unit. Dipeptidyl Peptidase IV (CD26) in Metabolism and the Immune Response, Austin Texas.
2. Born, I., Faust, J., Heins, J., Barth, A. and Neubert, K., 1994, Potent Inhibitors of Dipeptidyl Peptidase IV. Eur. Cell Biol. Suppl. 40:83.
3. Stöckel-Maschek, A., Stiebitz, B., Ḃorn, I., Faust, J., Mögelin, W.and Neubert, K., 2000, Potent Inhibitors of Dipeptidyl Peptidase IV and Their Mechanisms of Inhibition. Adv. Exp. Med. Biol. 477: 117-123.
4. Lorey, S., Stöckel-Maschek, A., Faust, J., Brandt, W., Stiebitz, B., Gorrell, M.D., Kähne, T., Mrestani-Klaus, C., Wrenger, S., Reinhold, D., Ansorge, S., Neubert, K., 2002, Different Modes of Dipeptidyl Peptidase IV (CD26) Inhibition by Oligopeptides derived from the N-terminus of HIV-1 Tat indicate at least two inhibitor binding sites. Submitted.
5. Segel, I.H., 1993, Enzyme Kinetics. John Wileys & Sons, Inc. New York.