Transcriptional repression of the testis-specific histone H1t gene mediated by an element upstream of the H1/AC box

Gene

Volumn 308, Issue 1-2, 2003, Pages 129-138

  Wolfe, Steven A ^a,b   Grimes, Sidney R ^a,b  

^a OVERTON BROOKS VA MEDICAL CENTER   (United States)

^b LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

DNA binding proteins; Gene regulation; Luciferase; Promoter element; Spermatogenesis

Indexed keywords

BINDING PROTEIN; HISTONE; HISTONE H1;

ANIMAL CELL; ARTICLE; CELL ASSAY; CELL STRAIN 3T3; GC RICH SEQUENCE; GENE ACTIVITY; GENE REPRESSION; GENETIC ANALYSIS; GENETIC PARAMETERS; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MALE; MOLECULAR BIOLOGY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; RAT; TESTIS;

ANIMALIA;

EID: 0038363401     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(03)00490-6     Document Type: Article

References (32)

1. Bartell J.G., Davis T., Kremer E.J., Dewey M.J., Kistler W.S. Expression of the rat testis-specific histone H1t gene in transgenic mice. One kilobase of 5′-flanking sequence mediates correct expression of a lacZ fusion gene. J. Biol. Chem. 271:1996;4046-4054.
2. Bucci L.R., Brock W.A., Meistrich M.L. Distribution and synthesis of histone 1 subfractions during spermatogenesis in the rat. Exp. Cell Res. 140:1982;111-118.
3. Celeste A., et al. Genomic instability in mice lacking histone H2AX. Science. 296:2002;922-927.
4. Chang Y.C., Illenye S., Heintz N.H. Cooperation of E2F-p130 and Sp1-pRb complexes in repression of the Chinese hamster dhfr gene. Mol. Cell. Biol. 21:2001;1121-1131.
5. Choi Y.C., Gu W., Hecht N.B., Feinberg A.P., Chae C.B. Molecular cloning of mouse somatic and testis-specific H2B histone genes containing a methylated CpG island. DNA Cell Biol. 15:1996;495-504.
6. Clare S.E., Fantz D.A., Kistler W.S., Kistler M.K. The testis-specific histone H1t gene is strongly repressed by a G/C-rich region just downstream of the TATA Box. J. Biol. Chem. 272:1997;33028-33036.
7. Clare S.E., Hatfield W.R., Fantz D.A., Kistler W.S., Kistler M.K. Characterization of the promoter region of the rat testis-specific histone H1t gene. Biol. Reprod. 56:1997;73-82.
8. Coles L.S., Wells J.R. An H1 histone gene-specific 5′ element and evolution of H1 and H5 genes. Nucleic Acids Res. 13:1985;585-594.
9. Dalton S., Wells J.R. A gene-specific promoter element is required for optimal expression of the histone H1 gene in S-phase. EMBO J. 7:1988;49-56.
10. Drabent B., Doenecke D. Testis-specific expression of the mouse histone gene H1t is regulated by several promoter elements. Biol. Reprod. 57:1997;1375-1383.
11. Fan Y., Sirotkin A., Russell R.G., Ayala J., Skoultchi A.I. Individual somatic H1 subtypes are dispensable for mouse development even in mice lacking the H1(0) replacement subtype. Mol. Cell. Biol. 21:2001;7933-7943.
12. Gallinari P., La Bella F., Heintz N. Characterization and purification of H1TF2, a novel CCAAT-binding protein that interacts with a histone H1 subtype-specific consensus element. Mol. Cell. Biol. 9:1989;1566-1575.
13. Gorgoni B., Maritano D., Marthyn P., Righi M., Poli V. C/EBP beta gene inactivation causes both impaired and enhanced gene expression and inverse regulation of IL-12 p40 and p35 mRNAs in macrophages. J. Immunol. 168:2002;4055-4062.
14. Grimes S.R. Jr. Nuclear proteins in spermatogenesis. Comp. Biochem. Physiol. B. 83:1986;495-500.
15. Hofmann M.C., Hess R.A., Goldberg E., Millan J.L. Immortalized germ cells undergo meiosis in vitro. Proc. Natl. Acad. Sci. USA. 91:1994;5533-5537.
16. Khadake J.R., Rao M.R. DNA- and chromatin-condensing properties of rat testes H1a and H1t compared to those of rat liver H1bdec; H1t is a poor condenser of chromatin. Biochemistry. 34:1995;15792-15801.
17. Koppel D.A., Wolfe S.A., Fogelfeld L.A., Merchant P.S., Prouty L., Grimes S.R. Primate testicular histone H1t genes are highly conserved and the human H1t gene is located on chromosome 6. J. Cell. Biochem. 54:1994;219-230.
18. La Bella F., Gallinari P., McKinney J., Heintz N. Histone H1 subtype-specific consensus elements mediate cell cycle-regulated transcription in vitro. Genes Dev. 3:1989;1982-1990.
19. Meergans T., Albig W., Doenecke D. Varied expression patterns of human H1 histone genes in different cell lines. DNA Cell Biol. 16:1997;1041-1049.
20. Philippe J. Hepatocyte-nuclear factor 3 beta gene transcripts generate protein isoforms with different transactivation properties on the glucagon gene. Mol. Endocrinol. 9:1995;368-374.
21. Singal R., van Wert J., Bashambu M., Wolfe S.A., Wilkerson D.C., Grimes S.R. Testis-specific histone H1t gene is hypermethylated in non-germinal cells in the mouse. Biol. Reprod. 63:2000;1237-1244.
22. Tanaka M., Hennebold J.D., Macfarlane J., Adashi E.Y. A mammalian oocyte-specific linker histone gene H1oo: homology with the genes for the oocyte-specific cleavage stage histone (cs-H1) of sea urchin and the B4/H1M histone of the frog. Development. 128:2001;655-664.
23. van Wert J.M., Panek H.R., Wolfe S.A., Grimes S.R. The TE promoter element of the histone H1t gene is essential for transcription in transgenic mouse primary spermatocytes. Biol. Reprod. 59:1998;704-710.
24. van Wijnen A.J., Wright K.L., Massung R.F., Gerretsen M., Stein J.L., Stein G.S. Two target sites for protein binding in the promoter region of a cell cycle regulated human H1 histone gene. Nucleic Acids Res. 16:1988;571-592.
25. Wang Z.F., Sirotkin A.M., Buchold G.M., Skoultchi A.I., Marzluff W.F. The mouse histone H1 genes: gene organization and differential regulation. J. Mol. Biol. 271:1997;124-138.
26. Wilkerson D.C., Wolfe S.A., Grimes S.R. The H1t/GC-box and the H1t/TE1 element are essential for promoter activity of the testis-specific histone H1t gene. Biol. Reprod. 67:2002;1157-1164.
27. Wilkerson D.C., Wolfe S.A., Grimes S.R. Sp1 and Sp3 activate the testis specific histone H1t promoter through the H1t/GC-box. J. Cell. Biochem. 86:2002;716-725.
28. Wolfe S.A., Grimes S.R. Binding of nuclear proteins to an upstream element involved in transcriptional regulation of the testis-specific histone H1t gene. J. Cell. Biochem. 75:1999;555-565.
29. Wolfe S.A., Grimes S.R. Tissue-specific binding to the RE element of the testis-specific histone gene. Biol. Reprod. ? 2003;? in press.
30. Wolfe S.A., Mottram P.J., van Wert J.M., Grimes S.R. Localization of upstream elements involved in transcriptional regulation of the rat testis-specific histone H1t gene in somatic cells. Biol. Reprod. 61:1999;1005-1011.
31. Wolfe S.A., van Wert J.M., Grimes S.R. Expression of the testis-specific histone H1t gene: evidence for involvement of multiple cis-acting promoter elements. Biochemistry. 34:1995;12461-12469.
32. Zlatanova J. Histone H1 and the regulation of transcription of eukaryotic genes. Trends Biochem. Sci. 15:1990;273-276.