Metabotropic receptor activation, desensitization and sequestration - I: Modelling calcium and inositol 1,4,5-trisphosphate dynamics following receptor activation

Journal of Theoretical Biology

Volumn 223, Issue 1, 2003, Pages 93-111

  Lemon, G ^a   Gibson, W G ^a   Bennett, M R ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Calcium; Desensitization; G protein; IP3; PIP2; PLC; Receptors; Sequestration

Indexed keywords

CALCIUM ION; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL 1,4,5 TRISPHOSPHATE; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR AGONIST; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; URIDINE TRIPHOSPHATE;

CALCIUM;

ARTICLE; CALCIUM MOBILIZATION; CELL MEMBRANE; CELL TYPE; CONCENTRATION RESPONSE; CYTOSOL; ENZYME DEFICIENCY; MATHEMATICAL MODEL; PREDICTION; PRIORITY JOURNAL; PROTEIN FUNCTION; RECEPTOR DOWN REGULATION; RECEPTOR SENSITIVITY; REGULATORY MECHANISM;

EID: 0038361339     PISSN: 00225193     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5193(03)00079-1     Document Type: Article

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