Histamine H1 receptor antagonism by cetirizine in isolated guinea pig tissues: Influence of receptor reserve and dissociation kinetics

European Journal of Pharmacology

Volumn 470, Issue 1-2, 2003, Pages 87-94

  Christophe, Bernard ^a   Carlier, Brigitte ^a   Gillard, Michel ^a   Chatelain, Pierre ^a   Peck, Mike ^a   Massingham, Roy ^a  

^a UCB PHARMA   (Belgium)

Author keywords

Cetirizine; Dissociation kinetic; Histamine H1 receptor antagonism; Ileum, guinea pig; Receptor reserve; Trachea, guinea pig

Indexed keywords

CALCIUM CHANNEL L TYPE; CALCIUM ION; CETIRIZINE; CHLORPHENIRAMINE; DEXTROCETIRIZINE; DIBENAMINE; HISTAMINE H1 RECEPTOR; HISTAMINE H1 RECEPTOR ANTAGONIST; LEVOCETIRIZINE; LORATADINE; MEPYRAMINE; RECEPTOR RESERVE; TERFENADINE; UNCLASSIFIED DRUG; HISTAMINE;

ANIMAL TISSUE; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DISSOCIATION; DRUG ACTIVITY; DRUG COMPETITION; DRUG EFFECT; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; ENANTIOMER; GUINEA PIG; ILEUM; ISOLATED ORGAN; KINETICS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT; RECEPTOR BLOCKING; TRACHEA; ANIMAL; AORTA; DOSE RESPONSE; IN VITRO STUDY; METABOLISM;

ANIMALS; AORTA; CETIRIZINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GUINEA PIGS; HISTAMINE; HISTAMINE H1 ANTAGONISTS; ILEUM; MALE; RATS; RECEPTORS, HISTAMINE H1; TRACHEA;

EID: 0038360972     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(03)01781-3     Document Type: Article

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