Enantiomeric separation of tocainide and its analogues on an optically active crown ether-based stationary phase by liquid chromatography

Journal of Chromatography A

Volumn 996, Issue 1-2, 2003, Pages 233-237

  Hyun, Myung Ho ^a   Min, Hye Jung ^a   Cho, Yoon Jae ^a  

^a Pusan National University   (South Korea)

Author keywords

Chiral stationary phases, LC; Crown ether based stationary phase; Enantiomer separation; Tocainide

Indexed keywords

AMMONIUM COMPOUNDS; CROWN ETHERS; SEPARATION; SILICA GEL; SOLUTIONS;

ENANTIOMERIC SEPARATION;

LIQUID CHROMATOGRAPHY;

AMMONIUM ACETATE; CROWN ETHER; SILICA GEL; TOCAINIDE;

AQUEOUS SOLUTION; ARTICLE; CHIRALITY; COVALENT BOND; ENANTIOMER; LIQUID CHROMATOGRAPHY; OPTICAL RESOLUTION; PRIORITY JOURNAL; SEPARATION TECHNIQUE;

EID: 0038359437     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9673(03)00540-5     Document Type: Article

References (17)

1. Crossley R. Chirality and the Biological Activity of Drugs. 1995;CRC Press, Boca Raton, FL.
2. Subramanian G. A Practical Approach to Chiral Separation by Liquid Chromatography. 1994;VCH, Weinheim.
3. Ahuja S. Chiral Separations by Chromatography. 2000;American Chemical Society/Oxford University Press, Washington, DC/Oxford.
4. Jamali F., Mehvar R., Pasutto F.M. J. Pharm. Sci. 78:1989;695.
5. Schill G., Wainer I.W., Barkan S.A. J. Liq. Chromatogr. 9:1986;641.
6. Andersson S., Allenmark S., Moller P., Persson B., Sanchez D. J. Chromatogr. A. 741:1996;23.
7. Shibukawa A., Nakagawa T. Krstulovic A.M. Chiral Separations by HPLC: Applications to Pharmaceutical Compounds. 1989;Ellis Horwood, Chichester. Chapter 16.
8. Aboul-Enein H.Y., Bark S.A., Islam M.R., Rothchild R. J. Liq. Chromatogr. 14:1991;3475.
9. Hyun M.H., Jin J.S., Lee W. J. Chromatogr. A. 822:1998;155.
10. Hyun M.H., Jin J.S., Koo H.J., Lee W. J. Chromatogr. A. 837:1999;75.
11. Hyun M.H., Han S.C., Jin J.S., Lee W. Chromatographia. 52:2000;473.
12. Hyun M.H., Han S.C., Lipshutz B.H., Shin Y.-J., Welch C.J. J. Chromatogr. A. 910:2001;359.
13. Hyun M.H., Han S.C., Lipshutz B.H., Shin Y.-J., Welch C.J. J. Chromatogr. A. 959:2002;75.
14. Kuhn R., Steinmetz C., Bereuter T., Haas P., Erni F. J. Chromatogr. A. 666:1994;367.
15. Schulze J., König W.A. J. Chromatogr. 355:1986;165.
16. Marle I., Erlandsson P., Hansson L., Isaksson R., Pettersson C., Pettersson G. J. Chromatogr. 586:1991;233.
17. Hyun M.H., Koo H.J., Jin J.S., Lee W. J. Liq. Chromatogr. Rel. Technol. 23:2000;2669.