Lettuce anaphylaxis: Identification of a lipid transfer protein as the major allergen

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 58, Issue 6, 2003, Pages 511-517

  San Miguel Moncin M ^a   Krail, M ^b   Scheurer, S ^b   Enrique, E ^a   Alonso, R ^a   Conti, A ^c   Cisteró Bahíma, Anna ^a   Vieths, S ^b  

^a INSTITUT UNIVERSITARI DEXEUS   (Spain)

^b PAUL EHRLICH INSTITUT   (Germany)

^c CNR   (Italy)

Author keywords

Cross reactivity; Food allergy; Immunoblotting inhibition; Lettuce allergy; Lipid transfer protein

Indexed keywords

ALLERGEN; IMMUNOGLOBULIN BINDING FACTOR; IMMUNOGLOBULIN E; LIPID TRANSFER PROTEIN; POLLEN ANTIGEN; POLLEN EXTRACT; RECOMBINANT ALLERGEN; UNCLASSIFIED DRUG;

ADULT; ALLERGENICITY; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANAPHYLAXIS; ARTICLE; BIRCH; CLINICAL ARTICLE; CROSS REACTION; DISEASE ASSOCIATION; EUROPE; EXTRACTION; FEMALE; FOOD ALLERGY; HUMAN; IMMUNOBLOTTING; LETTUCE; MALE; MEDITERRANEAN SEA; OROPHARYNX; PLANT; PLATANUS; POLLEN ALLERGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; SYSTEMIC DISEASE;

ADULT; ALLERGENS; AMINO ACID SEQUENCE; ANAPHYLAXIS; ANTIGENS, PLANT; CARRIER PROTEINS; CROSS REACTIONS; FEMALE; FOOD HYPERSENSITIVITY; HUMANS; LETTUCE; MALE; PLANT PROTEINS; POLLEN; SEQUENCE HOMOLOGY, AMINO ACID; TREES;

EID: 0038355434     PISSN: 01054538     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1398-9995.2003.00097.x     Document Type: Article

References (42)

1. ORTOLANI C, ISPANO M, PASTORELLO EA, BIGI A, ANSALONI R. The oral allergy syndrome. Ann Allergy 1988;61:47-52.
2. KAZEMI-SHIRAZI L, PAULI G, PUROHIT A, SPITZAUER S, FRÖSCHL R, HOFFMAN-SOMMERGRUBER K, BREITENEDER H, SCHEINER O, KRAFT D, VALENTA R. Quantitative IgE inhibition experiments with purified recombinant allergens indicate pollen-derived allergens as the sensitizing agents responsible for many forms of plant food allergy. J Allergy Clin Immunol 1999;105:116-125.
3. VIETHS S, REINDL J, MÜLLER U, HOFFMANN A, HAUSTEIN D. Digestibility of peanut and hazelnut allergens investigated by a simple in vitro procedure. Eur Food Res Technol 1999;209:379-388.
4. VIETHS S, SCHEURER S, BALLMER-WEBER BK. Current understanding of cross-reactivity of food allergens and pollen. Ann NY Acad Sci 2002;964:1-21.
5. PASTORELLO EA, ORTOLANI C, FARIOLI L, PRAVETTONI V, ISPANO M, BORGA A, BENGTSSON A, INCORVIA C, BERTI C, ZANUSSI C. Allergenic cross-reactivity among peach, apricot, plum and cherry in patients with oral allergy syndrome: an in vivo and in vitro study. J Allergy Clin immnunol 1994;94:699-707.
6. PASTORELLO EA, ORTOLANI C, FARIOLI L, PRAVETTONI V, ISPANO M, FORTUNATO D, MONZA M, GIUFFRIDA MG, RIVOLTA F, SCIBOLA E, ANSALONI R, INCORVAIA C, CONTI A. Cinical role of a lipid transfer proteins that acts as a new apple-specific allergen. J Allergy Clin Imnunol 1999;104:1099-1106.
7. SÁNCHEZ-MONGE R, LOMBARDERO M, GARCÍA-SELLES FJ, BARBER D, SALCEDO G. Lipid-transfer proteins are relevant allergens in fruit allergy. J Allergy Clin Immunol 1999;103:514-519.
8. ASERO R, MISTRELLO G, RONCAROLO D, DE VRIES SC, GAUTIER MF, CIURANA CLF, VERBEEK E, MOHAMMADI T, KNUL-BRETTLOVA V, AKKERDAAS JH, BULDER I, AALBERSE RC, van REE R. Lipid-transfer protein: a pan-allergen in plant-derived food that is highly resistant to pepsin digestion. Int Arch Allergy Immunol 2000;122:20-32.
9. DÍAZ-PERALES A, LOMBARDERO M, SÁNCHEZ-MONGE R. GARCÍA-SELLES FJ, PERNAS M, FERNÁNDEZ-RIVAS M, BARBER D, SALCEDO G. Lipid-transfer protein as potential plant-panallergens: cross-reactivity among proteins of Artemisia pollen, Castanea, nut and Rosaceae fruits, with different IgE-binding capacities. Clin Exp Allergy 2000;30:1403-1410.
10. SCHEURER S, PASTORELLO EA, WANGORSCH A, KÄSTNER EM, HAUSTEIN D, VIETHS S. Recombinant allergens Pru av 1 and Pru av 4 and a newly indentified lipid transfer protein in the in vitro diagnosis of cherry allergy. J Allergy Clin Immunol 2001;107:724-731.
11. HOFFMANN-SOMMERGRUBER K. Plant allergens and pathogenesis-related proteins. What do they have in common? Int Arch Allergy Immunol 2000;122:155-166.
12. VAN REE R, AALBERSE RC. Pollen-vegetable food crossreactivity: serologic and clinical relevance of crossreactive IgE. J Clin Immunoassay 1993;16:124-130.
13. VALENTA R, KRAFT D. TYPE I allergic reactions to plant-derived food: a consequence of primary sensitisation to pollen allergens. J Allergy Clin Immunol 1996;97:893-895.
14. DURO G, COLOMBO P, COSTA MA, IZZO V, PORCASSI R, DI FIORE R, LOCOROTONDO G, COCCHIARA R, GERACI D. Isolation and characterization of two cDNA clones coding for isoforms of the Parietaria judaica major allergen Par jl.0101. Int Arch Allergy Immunol 1997;112:348-355.
15. MIRALLES JC, CARAVACA F, GUILLÉN F, LOMBARDERO M, NEGRO JM. Cross-reactivity between Platanus pollen and vegetables. Allergy 2002;57:146-149.
16. ENRIQUE E, CISTERÓ-BAHIMA A, BARTOLOMÉ B, ALONSO R SAN MIGUEL-MONCÍN MM, BARTRA J, MARTÍNEZ A, Platanus acerifolia pollinosis and food allergy. Allergy 2002;57:351-356.
17. VILA L, SÁNCHEZ G, SANS ML, DIEGUEZ I, MARTÍNEZ A, PALACIOS R, MARTÍNEZ J. Study of a case of hypersensitivity to lettuce (Lactuca sativa). Clin Exp Allergy 1998;28:1031-1035.
18. KROOK G. Occupational dermatitis from Lactuca sativa (lettuce) and Chicorium (endive). Simultaneous occurrence of immediate and delayed allergy as a cause of contact dermatitis. Contact Dermatitis 1977;3:27-36.
19. OLIWIECKI S, BECK MH, HAUSEN BM. Compositae dermatitis aggravated by eating lettuce. Contact Dermatitis 1991;24:318-319.
20. ALONSO MD, MARTÍN JA, CUEVAS M, PARRA F, LEZAUN A, CONDE SALAZAR L, GUIMARAEN MD, LOSADA E. Occupational protein contact dermatitis from lettuce. Contact Dermatitis 1993;29:109-110.
21. KANERVA L, ESTLANDER T, JOLANKI R. Occupational allergy contact dermatitis from spices. Contact Dermatitis 1996;35:157-162.
22. PAULSEN E, SOGAARD J, ANDERSEN KE. Occupational dermatitis in Danish gardeners and greenhouse workers (III). Compositae-realted symptoms. Contact Dermatitis 1998;38:140-146.
23. PAULSEN E, ANDERSEN KE, HAUSEN BM. Sensitisation and cross-reaction patterns in Danish Compositae-allergic patients. Contact Dermatitis 2001;45:197-204.
24. HELBLING A, SCHAWARTZ HJ, LÓPEZ M, LEHRER SB. Lettuce and carrots allergy: are they related? Allergy Proc 1994;15:33-38.
25. CADOT P, KOCHUYT AM, DEMAN R, STEVENS EA. Inhalative occupational and ingestive immediate-type allergy caused by chicory (Chicorium intybus). Clin Exp Allergy 1996;26:940-944.
26. GARCÍA ORTÍZ JC, COSMES PM, LÓPEZ-ASUNSOLO A. Allergy to foods in patients monosensitized to Artemisia pollen. Allergy 1996;51:927-931.
27. ESCUDERO A, BARTOLOMÉ B, SÁNCHEZ-GUERRERO IM, PALACIOS R. Lettuce and chicory sensitisation. Allergy 1999;54:183-184.
28. FRANCK P, KANNY G, DOUSSET B, NABET P, MONERET-VAUTRIN DA. Lettuce allergy. Allergy 2000;55:201-202.
29. SAMPSON HA. Food allergy. Part 2: Diagnosis and management. J Allergy Clin Immunol 1999;103:981-989.
30. European Academy of Allergology and Clinical Immunology Subcomitte of Skin Tests and Allergen standarization. Skin tests used in type I allergy testing. Allergy 1989;44 (10 Suppl.):13-60.
31. DREBORG S, FOUCARD T. Allergy to apple, carrot and potato in children with birch pollen allergy. Allergy 1983;38:167-172.
32. VIETHS S, SCHÖNING B, PETERSEN A. Characterization of the 18-kDa apple allergen by two-dimensional immunoblotting and microsequencing. Int Arch Allergy Immunol 1994;104:399-404.
33. SCHEURER S, WANGORSCH A, NERKAMP J, SKOV PS, BALLMER-WEBER BK, WÜTHRICH B, HAUSTEIN D, VIETHS S. Cross-reactivity within the profilin panallergen family investigated by comparison of recombinant profilins from pear (Pyr c 4), cherry (Pru av 4), and celery (Api g 4) with birch pollen profilin (Bet v 2). J Chromatogr B 2001;756:315-325.
34. PASTORELLO EA, FARIOLI L, PRAVETTONI V, ORTOLANI C, ISPANO M, MONZA M, BAROGLIO C, SCIBOLA E, ANSOLONI R, INCORVAIA C, CONTI A. The major allergen of peach (Prunus persica) is a lipid transfer protein. J Allergy Clin Immunol 1999;103:520-526.
35. PASTORELLO EA, FARIOLI L, PRAVETTONI V, ISPANO M, SCIBOLA E, TRAMBAIOLI C, GIUFFRIDA MG, ANSALONI R, GODOVAC-ZIMMERMANN J, CONTI A, FORTUNATO D, ORTOLANI C. The maize major allergen, which is responsible for food-induced allergic reactions, is a lipid transfer protein. J Allergy Clin Immunol 2000;106:744-751.
36. BERNHISEL-BROADBENT J, SAMPSON HA. Cross-allergenicity in the legume botanical family in children with food hypersensitivity. J Allergy Clin Immunol 1989;83:435-440.
37. LÜTTKOPF D, BALLMER-WEBER BK, WÜTHRICH B, VIETHS S. Celery allergens in patients with positive double-blind placebo-controlled food challenge. J Allergy Clin Immunol 2000;106:390-399.
38. MOLINA A, SEGURA A, GARCÍA-OLMEDO F. Lipid transfer proteins (nsLTP) from barley and maize leaves are potent inhibitors of bacterial and fungal plant pathogens. FEBS Lett 1993;316:119-122.
39. FERNÁNDEZ-RIVAS M, Van REE R, CUEVAS M. Allergy to Rosacea fruits without related pollinosis. J Allergy Clin Immunol 1997;100:728-733.
40. PASTORELLO EA, POMPEI C, PRAVETTONI V, BRENNA O, FARIOLI L, TRAMBAJOLI C, CONTI A. Lipid transfer proteins and 2S albumins as allergens. Allergy 2001;5:Suppl. 67:45-47.
41. BREITENEDER H, EBNER C. Molecular and biochemical classification of plant-derived food allergens. J Allergy Clin Immunol 2000;106:27-36.
42. PASTORELLO EA, PURELLO DAMBROSIO F, PRAVETTONI V, FARIOLI L, GIUFFRIDA G, MONZA M, ANSALONI R, FORTUNATO D, SCIBOLA E, RIVOLTA F, INCORVAIA C, BENGTSSON A, CONTI A, ORTOLANI C. Evidence for a lipid transfer protein as the major allergen of apricot. J Allergy Clin Immunol 2000;105:371-377.