Role of the mannose-binding lectin in innate immunity

Journal of Infectious Diseases

Volumn 187, Issue SUPPL. 2, 2003, Pages

  Ezekowitz, R Alan ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CYTOKINE; LECTIN; MANNOSE BINDING PROTEIN;

ALLELE; ANTIBODY PRODUCTION; AUTOIMMUNITY; CONFERENCE PAPER; CORRELATION ANALYSIS; CYTOKINE RELEASE; GENETIC CORRELATION; GENETIC VARIABILITY; HAPLOTYPE; HOST PATHOGEN INTERACTION; HOST RESISTANCE; HUMAN; IMMUNOREGULATION; INFECTION; INFECTION PREVENTION; INFECTION RESISTANCE; INFECTION SENSITIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION;

ALLELES; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; IMMUNITY, NATURAL; MANNOSE-BINDING LECTIN; PROTEIN CONFORMATION; VARIATION (GENETICS);

EID: 0038348638     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/374746     Document Type: Conference Paper

References (37)

1. Hoffmann JA, Kafatos FC, Janeway CA, Ezekowitz RA. Phylogenetic perspectives in innate immunity. Science 1999; 284:1313-8.
2. Wright AF, Carothers AD, Pirastu M. Population choice in mapping genes for complex diseases. Nat Genet 1999; 23:397-404.
3. Kawasaki T, Etoh R, Yamashina I. Isolation and characterization of a mannan-binding protein from rabbit liver. Biochem Biophys Res Commun 1978; 81:1018-24.
4. Drickamer K, Dordal MS, Reynolds L. Mannose-binding proteins isolated from rat liver contain carbohydrate-recognition domains linked to collagenous tails. Complete primary structures and homology with pulmonary surfactant apoprotein. J Biol Chem 1986; 261:6878-87.
5. Ikeda K, Sannoh T, Kawasaki N, Kawasaki T, Yamashina I. Serum lectin with known structure activates complement through the classical pathway. J Biol Chem 1987; 262:7451-4.
6. Ezekowitz RA, Day LE, Herman GA. A human mannose-binding protein is an acute-phase reactant that shares sequence homology with other vertebrate lectins. J Exp Med 1988; 167:1034-46 [erratum: J Exp Med 1991; 174:753].
7. Kuhlman M, Joiner K, Ezekowitz RAB. The human mannose-binding protein functions as an opsonin. J Exp Med 1989; 169:1733-45.
8. Ezekowitz RAB, Kuhlman M, Groopman J, Byrn R. A human serum mannose-binding protein inhibits in vitro infection by the human immunodeficiency virus. J Exp Med 1989; 169:185-96.
9. Sastry K, Herman GA, Day L, et al. The human mannose-binding protein gene. Exon structure reveals its evolutionary relationship to a human pulmonary surfactant gene and its localization to chromosome 10. J Exp Med 1989; 170:1175-89.
10. Sastry K, Zahedi K, Lelias JM, Whitehead AS, Ezekowitz RA. Molecular characterization of the mouse mannose-binding proteins. The mannose-binding protein A but not C is an acute phase reactant. J Immunol 1991; 147:692-7.
11. Super M, Thiel S, Lu J, Levinsky RJ, Turner MW. Association of low levels of mannan-binding protein with a common defect of opsonization. Lancet 1989; 2:1236-9.
12. Sumiya M, Super M, Tabona P, et al. Molecular basis of opsonic defect in immunodeficient children. Lancet 1991; 337:1569-70.
13. Madsen HO, Garred P, Thiel S, et al. Interplay between promoter and structural gene variants control basal serum level of mannan-binding protein. J Immunol 1995; 155:3013-20.
14. Madsen HO, Satz ML, Hogh B, Svejgaard A, Gaffed P. Different molecular events results in low protein levels of mannose-binding lectin in populations from southeast Africa and South America. J Immunol 1998; 161:3169-75.
15. Epstein J, Eichbaum Q, Sheriff S, Ezekowitz RAB. The collectins in innate immunity. Curr Opin Immunol 1996; 8:29-35.
16. Matsushita M, Fujita T. Activation of the classical complement pathway by mannose-binding protein in association with a novel C1s-like serine protease. J Exp Med 1992; 176:1497-502.
17. Gadjeva M, Thiel S, Jensenius JC. The mannan-binding-lectin pathway of the innate immune response. Curr Opin Immunol 2001; 13:74-8.
18. Dahl MR, Thiel S, Matsushita M, et al. MASP-3 and its association with distinct complexes of the mannan-binding lectin complement activation pathway. Immunity 2001; 15:127-35.
19. Janeway CAJ. Approaching the asymptote: evolution and revolution in immunology. Cold Spring Harbor Symp Quant Biol 1989; 54:1-13.
20. Weis WI, Drickamer K, Hendrickson WA. Structure of a C-type mannose-binding protein complexed with an oligosaccharide. Nature 1992; 360:127-34.
21. Kawasaki N, Kawasaki T, Yamashina I. Isolation and characterization of a mannan-binding protein from human serum. J Biochem (Tokyo) 1983; 94:937-47.
22. Sheriff S, Chang CY, Ezekowitz RA. Human mannose-binding protein carbohydrate recognition domain trimerizes through a triple alpha-helical coiled-coil. Nat Struct Biol 1994; 1:789-94 [erratum: Nat Struc Biol 1996; 3:103].
23. Reid KB. Functional roles of the lung surfactant proteins SP-A and SP-D in innate immunity. Immunobiology 1998; 199:200-7.
24. Madsen HO, Garred P, Kurtzhals JA, et al. A new frequent allele is the missing link in the structural polymorphism of the human mannan-binding protein. Immunogenetics 1994; 40:37-44.
25. Jack DL, Read RC, Tenner AJ, Frosch M, Turner MW, Klein NJ. Mannose-binding lectin regulates the inflammatory response of human professional phagocytes to Neisseria meningitidis serogroup B. J Infect Dis 2001; 184:1152-62.
26. Lipscombe RJ, Sumiya M, Hill AV, et al. High frequencies in African and non-African populations of independent mutations in the mannose binding protein gene. Hum Mol Genet 1992; 1:709-15; [erratum: Hum Mol Genet 1993; 2:342].
27. Ezekowitz RAB. Genetic heterogeneity of mannose-binding proteins: the Jekyll and Hyde of innate immunity? Am J Hum Genet 1998; 62:6-9.
28. Turner MW. Mannose-binding lectin (MBL) in health and disease. Immunobiology 1998; 199:327-39.
29. Garred P, Pressler T, Madsen HO, et al. Association of mannose-binding lectin gene heterogeneity with severity of lung disease and survival in cystic fibrosis. J Clin Invest 1999; 104:369-70.
30. Bodey GP, Buckley M, Sathe YS, Freireich EJ. Quantitative relationships between circulating leukocytes and infection in patients with acute leukemia. Ann Intern Med 1966; 64:328-40.
31. Talcott JA. Out-patient management of febrile neutropenia. Int J Antimicrob Agents 2000; 16:169-71.
32. Neth O, Hann I, Turner MW, Klein NJ. Deficiency of mannose-binding lectin and burden of infection in children with malignancy: a prospective study. Lancet 2001; 358:614-8.
33. Peterslund NA, Koch C, Jensenius JC, Thiel S. Association between deficiency of mannose-binding lectin and severe infections after chemotherapy. Lancet 2001; 358:637-8.
34. Luty AJ, Kun JF, Kremsner PG. Mannose-binding lectin plasma levels and gene polymorphisms in Plasmodium falciparum malaria. J Infect Dis 1998; 178:1221-4.
35. Kelly P, Jack DL, Naeem A, et al. Mannose-binding lectin is a component of innate mucosal defense against Cryptosporidium parvum in AIDS. Gastroenterology 2000; 119:1236-42.
36. Santos IK, Costa CH, Krieger H, et al. Mannan-binding lectin enhances susceptibility to visceral leishmaniasis. Infect Immun 2001; 69:5212-5.
37. Takahashi K, Gordon J, Liu H, et. al, Lack of mannose-binding lectin-A enhances survival in a mouse model of acute septic peritonitis. Microbes Infect 2002; 4:773-84.