Successful T-cell-replete peripheral blood stem cell transplantation from HLA-haploidentical microchimeric mother to daughter with refractory acute lymphoblastic leukemia using reduced-intensity conditioning

Bone Marrow Transplantation

Volumn 31, Issue 11, 2003, Pages 1061-1063

  Umeda, K ^a   Adachi, S ^a   Ishihara, H ^a   Higashi, Y ^a   Shiota, M ^a   Watanabe, K I ^a   Hishizawa, M ^a   Ichinohe, T ^a   Kitoh, T ^b   Maruya, E ^c   Saji, H ^c   Uchiyama, T ^a   Nakahata, T ^a  

^a KYOTO UNIVERSITY   (Japan)

^b UNIVERSITY OF FUKUI   (Japan)

^c Japanese Red Cross Kanto Koshinetsu Block Blood Center   (Japan)

Author keywords

Acute lymphoblastic leukemia; Graft versus host disease; Graft versus leukemia effect; Long term fetomaternal microchimerism

Indexed keywords

FLUDARABINE; HLA ANTIGEN; IMMUNOSUPPRESSIVE AGENT; LACTATE DEHYDROGENASE; MELPHALAN; METHOTREXATE; PREDNISOLONE; TACROLIMUS;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ARTICLE; CASE REPORT; DISEASE SEVERITY; DONOR; FATHER; FEMALE; GRAFT VERSUS HOST REACTION; HAPLOTYPE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HLA MATCHING; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INHERITANCE; LEUKEMIA REMISSION; MICROCHIMERISM; MOTHER; PERIPHERAL BLOOD STEM CELL; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; T LYMPHOCYTE; THROMBOCYTOPENIA; THROMBOTIC THROMBOCYTOPENIC PURPURA; WHOLE BODY RADIATION;

ADOLESCENT; FEMALE; HUMANS; LEUKEMIA, LYMPHOCYTIC, ACUTE; MOTHERS; STEM CELL TRANSPLANTATION; TIME FACTORS; TISSUE DONORS; TRANSPLANTATION CONDITIONING; TREATMENT OUTCOME; WHOLE-BODY IRRADIATION;

EID: 0038347465     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1704057     Document Type: Article

References (7)

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6. Ochiai N, Shimazaki C, Fuchida S et al. Successful non-T-cell depleted HLA haplo-identical 3-loci mismatched hematopoietic stem cell transplantation from mother to son based on the feto-maternal michrochimerism in chronic myelogeneous leukemia. Bone Marrow Transplant 2002; 30: 793-796.
7. Girait S, Thall PF, Khouri I et al. Melphalan and purine analog-containing preparative regimens: reduced-intensity conditioning for patients with hematologic malignancies undergoing allogeneic progenitor cell transplantation. Blood 2001; 97: 631-637.