-
1
-
-
0037068964
-
Clinical importance of the cytochromes
-
P450
-
Nebert DW, Russell DW. Clinical importance of the cytochromes. P450. Lancet 2002; 360: 1155-62
-
(2002)
Lancet
, vol.360
, pp. 1155-1162
-
-
Nebert, D.W.1
Russell, D.W.2
-
2
-
-
0036882141
-
Why does smoking protect against PONV?
-
Sweeney BP. Why does smoking protect against PONV? Br J Anaesth 2002; 89: 1-4
-
(2002)
Br. J. Anaesth.
, vol.89
, pp. 1-4
-
-
Sweeney, B.P.1
-
3
-
-
0012676670
-
Geographical/interracial differences in polymorphic drug oxidation
-
Bertilsson L. Geographical/interracial differences in polymorphic drug oxidation. Clin Pharmacokinet 1955; 29: 129-209
-
(1955)
Clin. Pharmacokinet.
, vol.29
, pp. 129-209
-
-
Bertilsson, L.1
-
4
-
-
0032706623
-
A general approach to single nucleotide polymorphism discovery
-
Marth GT, Korf I, Yandell MD, et al. A general approach to single nucleotide polymorphism discovery. Nature Genet 1999; 23: 452-6
-
(1999)
Nature Genet.
, vol.23
, pp. 452-456
-
-
Marth, G.T.1
Korf, I.2
Yandell, M.D.3
-
5
-
-
0000616920
-
Enzymatic deficiency in promaquine-sensitive erythrocytes
-
Carsen PE, Flanagan CL, Iokes CE. Enzymatic deficiency in promaquine-sensitive erythrocytes. Science 1956; 124: 484-5
-
(1956)
Science
, vol.124
, pp. 484-485
-
-
Carsen, P.E.1
Flanagan, C.L.2
Iokes, C.E.3
-
6
-
-
0006948626
-
Metabolism of isoniazide in man as related to the occurrence of peripheral neuritis
-
Hughes HB, Biehl JP, Jones AP. Metabolism of isoniazide in man as related to the occurrence of peripheral neuritis. Am Rev Tuberculosis 1954; 70: 266-73
-
(1954)
Am. Rev. Tuberculosis
, vol.70
, pp. 266-273
-
-
Hughes, H.B.1
Biehl, J.P.2
Jones, A.P.3
-
7
-
-
0030426571
-
N-Acetyltransferases: Pharmacogenetics and clinical consequences of polymorphic drug metabolism
-
Spielberg SP. N-Acetyltransferases: pharmacogenetics and clinical consequences of polymorphic drug metabolism. J Pharmacokinet Biopharm 1996; 24: 509-19
-
(1996)
J. Pharmacokinet. Biopharm.
, vol.24
, pp. 509-519
-
-
Spielberg, S.P.1
-
9
-
-
0017695082
-
Polymorphic hydroxylation of debrisoquine in man
-
Mahgoub A, Idle JR, Dring LG, Lancater R, Smith RL. Polymorphic hydroxylation of debrisoquine in man. Lancet 1977; 2: 584-6
-
(1977)
Lancet
, vol.2
, pp. 584-586
-
-
Mahgoub, A.1
Idle, J.R.2
Dring, L.G.3
Lancater, R.4
Smith, R.L.5
-
10
-
-
0344938358
-
Inhibition and induction of human cytochrome P450 (CYP) enzymes
-
Pelkonen O, Maenpa J, Taavitsainen P, Rautio A, Raunio H. Inhibition and induction of human cytochrome P450 (CYP) enzymes. Xenobiotica 1998; 28: 1203-53
-
(1998)
Xenobiotica
, vol.28
, pp. 1203-1253
-
-
Pelkonen, O.1
Maenpa, J.2
Taavitsainen, P.3
Rautio, A.4
Raunio, H.5
-
11
-
-
0025805934
-
Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolisers of the debrisoquine/sparteine polymorphism
-
Gaedigk A, Blum M, Gaedigk R, Eichelbaum M, Meyer UA. Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolisers of the debrisoquine/sparteine polymorphism. Am J Hum Genet 1991; 48: 943-50
-
(1991)
Am. J. Hum. Genet.
, vol.48
, pp. 943-950
-
-
Gaedigk, A.1
Blum, M.2
Gaedigk, R.3
Eichelbaum, M.4
Meyer, U.A.5
-
12
-
-
0025950370
-
Debrisoquine/sparteine hydroxylation genotype and phenotype: Analysis of common mutations and alleles of CYP2D6 in a European population
-
Broly F, Gaedigk A, Heim M, Eichelbaum M, Kroemer HK. Debrisoquine/sparteine hydroxylation genotype and phenotype: analysis of common mutations and alleles of CYP2D6 in a European population. DNA Cell Biol 1991; 10: 545-58
-
(1991)
DNA Cell Biol.
, vol.10
, pp. 545-558
-
-
Broly, F.1
Gaedigk, A.2
Heim, M.3
Eichelbaum, M.4
Kroemer, H.K.5
-
13
-
-
0030472254
-
Codeine and morphine in extensive and poor metabolisers of sparteine: Pharmacokinetics, analgesic effects and side efects
-
Poulsen L, Brosen K, Arendt-Nielsen L. Codeine and morphine in extensive and poor metabolisers of sparteine: pharmacokinetics, analgesic effects and side efects. Eur J Clin Pharmacol 1996; 51: 289-95
-
(1996)
Eur. J. Clin. Pharmacol.
, vol.51
, pp. 289-295
-
-
Poulsen, L.1
Brosen, K.2
Arendt-Nielsen, L.3
-
14
-
-
0030432381
-
Pharmacogenetic determination of the effects of codeine and prediction of drug interactions
-
Caraco Y, Sheller J, Wood AJ. Pharmacogenetic determination of the effects of codeine and prediction of drug interactions. J Pharmacol Exp Ther 1996; 278: 1165-74
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.278
, pp. 1165-1174
-
-
Caraco, Y.1
Sheller, J.2
Wood, A.J.3
-
15
-
-
0031413420
-
Quantification of the O- and N-demethylated and the glucuronidated metabolites of codeine relative to the debrisoquine metabolic ratio in urine in ultrarapid, rapid, and poor debrisoquine hydroxylators
-
Yue Q, Alm C, Svensson J, Sawe J. Quantification of the O- and N-demethylated and the glucuronidated metabolites of codeine relative to the debrisoquine metabolic ratio in urine in ultrarapid, rapid, and poor debrisoquine hydroxylators. Ther Drug Monit 1997; 19: 539-42
-
(1997)
Ther. Drug Monit.
, vol.19
, pp. 539-542
-
-
Yue, Q.1
Alm, C.2
Svensson, J.3
Sawe, J.4
-
18
-
-
33947223647
-
Pharmacogenomics: The promise of personalised medicine
-
Mancinelli L, Cronin M, Sadee W. Pharmacogenomics: the promise of personalised medicine. AAPS Pharm Sci 2000; 2: 30-7
-
(2000)
AAPS Pharm. Sci.
, vol.2
, pp. 30-37
-
-
Mancinelli, L.1
Cronin, M.2
Sadee, W.3
-
19
-
-
0033816613
-
Relationship of polymorphism in CYP2C9 to genetic susceptibility to diclofenac-induced hepatitis
-
Aithal GP, Day CP, Leathart JBS. Relationship of polymorphism in CYP2C9 to genetic susceptibility to diclofenac-induced hepatitis. Pharmacogenetics 2000; 10: 511-18
-
(2000)
Pharmacogenetics
, vol.10
, pp. 511-518
-
-
Aithal, G.P.1
Day, C.P.2
Leathart, J.B.S.3
-
20
-
-
0036264127
-
Volatile anaesthetics may be the main cause of early but not delayed postoperative vomiting: A randomised controlled trial of factorial design
-
Apfel CC, Kranke P, Katz MH, et al. Volatile anaesthetics may be the main cause of early but not delayed postoperative vomiting: a randomised controlled trial of factorial design. Br J Anaesth 2002; 88: 659-68
-
(2002)
Br. J. Anaesth.
, vol.88
, pp. 659-668
-
-
Apfel, C.C.1
Kranke, P.2
Katz, M.H.3
-
21
-
-
0027515708
-
Identification of cytochrome P450 2EI as the predominant enzyme catalysing human liver microsomal defluorination of sevoflurane, isoflurane and methoxyflurane
-
Kharasch ED, Thummel KE. Identification of cytochrome P450 2EI as the predominant enzyme catalysing human liver microsomal defluorination of sevoflurane, isoflurane and methoxyflurane. Anesthesiology 1993; 79: 795-807
-
(1993)
Anesthesiology
, vol.79
, pp. 795-807
-
-
Kharasch, E.D.1
Thummel, K.E.2
-
22
-
-
0026062622
-
Genetic polymorphisms in the 5′-flanking region change transcriptional regulation of the human cytochrome P4502EI gene
-
Hayashi S, Watanabe J, Kawajiri K. Genetic polymorphisms in the 5′-flanking region change transcriptional regulation of the human cytochrome P4502EI gene. J Biochem 1991; 110: 559-65
-
(1991)
J. Biochem.
, vol.110
, pp. 559-565
-
-
Hayashi, S.1
Watanabe, J.2
Kawajiri, K.3
-
23
-
-
0008473038
-
Genetic factors contribute to the risk of postoperative nausea and vomiting, results of a twin study
-
Reavley CM, Cherkas L, Spector TD, MacGregor AJ. Genetic factors contribute to the risk of postoperative nausea and vomiting, results of a twin study. Br J Anaesth 1999: 82 (suppl. 1): 1-2
-
(1999)
Br. J. Anaesth.
, vol.82
, Issue.SUPPL. 1
, pp. 1-2
-
-
Reavley, C.M.1
Cherkas, L.2
Spector, T.D.3
MacGregor, A.J.4
-
24
-
-
0027731547
-
Ethanol inducible cytochrome P4502EI: Genetic polymorphism, regulation and possible role in the aetiology of alcohol-induced liver disease
-
Ingelman-Sundberg M, Johansson I, Yin H, et al. Ethanol inducible cytochrome P4502EI: genetic polymorphism, regulation and possible role in the aetiology of alcohol-induced liver disease. Alcohol 1993; 10: 447-52
-
(1993)
Alcohol
, vol.10
, pp. 447-452
-
-
Ingelman-Sundberg, M.1
Johansson, I.2
Yin, H.3
-
25
-
-
0032438847
-
Interindividual variability in P-450 dependent generation of neoantigens in halothane hepatitis
-
Eliasson E, Gardner I, Hume-Smith H, de Waziers I, Beaune P, Kenna JG. Interindividual variability in P-450 dependent generation of neoantigens in halothane hepatitis. Chem Biol Interact 1998; 116: 123-41
-
(1998)
Chem. Biol. Interact.
, vol.116
, pp. 123-141
-
-
Eliasson, E.1
Gardner, I.2
Hume-Smith, H.3
de Waziers, I.4
Beaune, P.5
Kenna, J.G.6
-
26
-
-
0034077954
-
The effect of smoking on postoperative nausea and vomiting
-
Chimbira W, Sweeney BP. The effect of smoking on postoperative nausea and vomiting. Anaesthesia 2000; 55: 540-5
-
(2000)
Anaesthesia
, vol.55
, pp. 540-545
-
-
Chimbira, W.1
Sweeney, B.P.2
-
27
-
-
13144261678
-
Single nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity. Possible implications for opiate addiction
-
Bond C, LaForge KS, Tian M. Single nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity. Possible implications for opiate addiction. Proc Natl Acad Sci USA 1998; 95: 9608-13
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 9608-9613
-
-
Bond, C.1
LaForge, K.S.2
Tian, M.3
-
28
-
-
0034087446
-
Ryanodine receptor mutations in malignant hyperthermia and central core disease
-
McCarthy TV, Quane KA, Lynch PJ. Ryanodine receptor mutations in malignant hyperthermia and central core disease. Hum Mutat 2000; 15: 410-7
-
(2000)
Hum. Mutat.
, vol.15
, pp. 410-417
-
-
McCarthy, T.V.1
Quane, K.A.2
Lynch, P.J.3
-
29
-
-
0036172251
-
The influence of genomics on outcome after cardiovascular surgery
-
Stueber F, Hoeft A. The influence of genomics on outcome after cardiovascular surgery. Curr Opin Anaesth 2002; 15: 3-8
-
(2002)
Curr. Opin. Anaesth.
, vol.15
, pp. 3-8
-
-
Stueber, F.1
Hoeft, A.2
-
30
-
-
0035033019
-
Pharmacogenomics: Unlocking the human genome for better drug therapy
-
McLeod HL, Evans WE. Pharmacogenomics: unlocking the human genome for better drug therapy. Annu Rev Toxicol 2001; 41: 101-21
-
(2001)
Annu. Rev. Toxicol.
, vol.41
, pp. 101-121
-
-
McLeod, H.L.1
Evans, W.E.2
|