Pharmacodynamics of a novel des-F(6)-quinolone, BMS-284756, against Streptococcus pneumoniae in the thigh infection model

Antimicrobial Agents and Chemotherapy

Volumn 47, Issue 5, 2003, Pages 1630-1635

  Nicolau, David P ^a   Mattoes, Holly M ^a   Banevicius, Maryanne ^a   Xuan, Dawei ^a   Nightingale, Charles H ^a  

^a HARTFORD HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHOSPHAMIDE; GARENOXACIN;

ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BACTERIAL SURVIVAL; BACTERICIDAL ACTIVITY; BACTERIUM ISOLATE; COLONY FORMING UNIT; DRUG BLOOD LEVEL; DRUG PROTEIN BINDING; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; IMMUNOCOMPETENCE; LEUKOCYTE COUNT; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NEUTROPENIA; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PNEUMONIAE; THIGH;

ANIMALS; ANTI-INFECTIVE AGENTS; AREA UNDER CURVE; DISEASE MODELS, ANIMAL; FLUOROQUINOLONES; INDOLES; MICE; MICE, INBRED CBA; MICE, INBRED ICR; MICROBIAL SENSITIVITY TESTS; PNEUMOCOCCAL INFECTIONS; PROTEIN BINDING; QUINOLONES; STREPTOCOCCUS PNEUMONIAE; THIGH;

EID: 0038335015     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.47.5.1630-1635.2003     Document Type: Article

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