Beneficial hemodynamic and renal effects of intravenous enalaprilat following coronary artery bypass surgery complicated by left ventricular dysfunction

Critical Care Medicine

Volumn 31, Issue 5, 2003, Pages 1421-1428

  Wagner, Frank ^a   Yeter, Ruhi ^a   Bisson, Susanne ^b   Siniawski, Henryk ^a   Hetzer, Roland ^a  

^a DEUTSCHES HERZZENTRUM BERLIN   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Angiotensin; Enalaprilat; Heart failure; Hemodynamics; Pharmacology; Surgery

Indexed keywords

CREATININE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRILAT; PLACEBO;

ADULT; AGED; AORTA BALLOON; ARTERIAL OXYGEN SATURATION; ARTERIAL PRESSURE; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY BYPASS SURGERY; COUNTERPULSATION; CREATININE CLEARANCE; DIASTOLE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; FEMALE; GERMANY; HEART INDEX; HEART LEFT VENTRICLE FAILURE; HEART RATE; HEART RIGHT VENTRICLE FUNCTION; HEART STROKE VOLUME; HEMODYNAMICS; HUMAN; INTENSIVE CARE UNIT; KIDNEY FUNCTION; LUNG ARTERY PRESSURE; LUNG VASCULAR RESISTANCE; MALE; MEAN ARTERIAL PRESSURE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; SYSTEMIC VASCULAR RESISTANCE;

ADULT; AGED; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; BLOOD GAS ANALYSIS; BLOOD UREA NITROGEN; CORONARY ARTERY BYPASS; CREATININE; DOUBLE-BLIND METHOD; DRUG MONITORING; ENALAPRILAT; FEMALE; HEMODYNAMIC PROCESSES; HUMANS; INFUSIONS, INTRAVENOUS; KIDNEY; MALE; METABOLIC CLEARANCE RATE; MIDDLE AGED; POSTOPERATIVE CARE; SAFETY; TIME FACTORS; TREATMENT OUTCOME; VENTRICULAR DYSFUNCTION, LEFT;

EID: 0038324080     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000063050.66813.39     Document Type: Article

References (37)

1. The CONSENSUS Trial Study Group: Effects of enalapril on mortality in severe congestive heart failure: Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). N Engl J Med 1987; 316:1429-1435
2. The SOLVD Investigators: Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. N Engl J Med 1991; 325:293-302
3. The SOLVD Investigators. Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions. N Engl J Med 1992; 327:685-691
4. Pfeffer MA, Braunwald E, Moyé LA, et al: Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction: Results of the survival and ventricular enlargement trial. N Engl J Med 1992; 327:669-677
5. Weintraub WS, Jones EL, Craver J, et al: Determinants of prolonged length of hospital stay after coronary bypass surgery. Circulation 1989; 80:276-284
6. Geraci JM, Rosen AK, Ash AS, et al: Predicting the occurrence of adverse events after coronary artery bypass surgery. Ann Intern Med 1993; 118:18-24
7. Elefteriades JA, Tolis G Jr, Levi E, et al: Coronary artery bypass grafting in severe left ventricular dysfunction: Excellent survival with improved ejection fraction and functional state. J Am Coll Cardiol 1993; 22:1411-1417
8. Pagley PR, Beller GA, Watson DD, et al: Improved outcome after coronary bypass surgery in patients with ischemic cardiomyopathy and residual myocardial viability. Circulation 1997; 96:793-800
9. Tohmo H, Karanko M, Klossner J, et al: Enalaprilat decreases plasma endothelin and atrial natriuretic peptide levels and preload in patients with left ventricular dysfunction after cardiac surgery. J Cardiothorac Vasc Anaesth 1997; 11:585-590
10. Chatterjee K, De Marco T: Systemic and coronary haemodynamics and pharmacodynamics of enalapril and enalaprilat in congestive heart failure. Drugs 1990; 39(Suppl 4):29-42
11. Taylor KM, Morton IJ, Brown JJ, et al: Hypertension and the renin-angiotensin system following open-heart surgery. J Thorac Cardiovasc Surg 1977; 74:840-845
12. Boldt J, Menges T, Wollbrück M, et al: Continuous i. v. administration of the angiotensin-converting enzyme inhibitor enalaprilat in the critically ill: Effects on regulators of circulatory homeostasis. J Cardiovasc Pharmacol 1995; 25:416-423
13. Böttiger BW, Rauch H, Böhrer H, et al: Continuous versus intermittent cardiac output measurement in cardiac surgical patients undergoing hypothermic cardiopulmonary by-pass. J Cardiothorac Vasc Anesth 1995; 9:405-411
14. Boldt J, Menges T, Wollbrück M, et al: Is continuous cardiac output measurement using thermodilution reliable in the critically ill patient? Crit Care Med 1994; 22:1913-1918
15. Oelkers W, Schöneshöfer M, Blümel A: Effects of progesterone and four synthetic progestagens on sodium balance and the renin-aldosterone system in man. J Clin Endocrinol Metab 1974; 39:882-890
16. Sehested J, Thomas F, Thorn M, et al: Level and diurnal variations of hormones of interest to the cardiovascular system in patients with heart transplants. Am J Cardiol 1992; 69:397-402
17. Weicker H, Feraudi M, Hägele H, et al: Electrochemical detection of catecholamines in urine and plasma after separation with HPLC. Clin Chim Acta 1984; 141:17-25
18. Waeber B, Brunner HR, Brunner DB, et al: Discrepancy between antihypertensive effect and angiotensin converting enzyme inhibition by captopril. Hypertension 1980; 2:236-242
19. Thomo H, Karanko M, Korpilahti K, et al: Enalaprilat in acute intractable heart failure after myocardial infarction: A prospective, consecutive sample, before-after trial. Crit Care Med 1994; 22:965-973
20. Podbregar M, Voga G, Horvat M, et al: Bolus versus continuous low dose of enalaprilat in congestive heart failure with acute refractory decompensation. Cardiology 1999; 91:41-49
21. Semple PF, Cumming AM, Meredith PA, et al: Onset of action of captopril, enalapril, enalaprilic acid and lisinopril in normal man. Cardiovasc Drugs Ther 1987; 1:45-50
22. Kubo SH, Cody RJ, Laragh JH, et al: Immediate converting enzyme inhibition with intravenous enalapril in chronic congestive heart failure. Am J Cardiol 1985; 55:122-126
23. Taylor SH, Verma SP, Silke B: Enalaprilat in heart failure complicating acute myocardial infarction. Curr Opin Cardiol 1989; 4(Suppl 2):537-543
24. Vrobel TR, Cohn JN: Comparative hemodynamic effects of converting enzyme inhibitor and sodium nitroprusside in severe heart failure. Am J Cardiol 1980; 45:331-336
25. Schuetz WH, Lindner KH, Georgieff M, et al: The effect of i. v. enalaprilat in chronically treated hypertensive patients during cardiac surgery. Acta Anaesthesiol Scand 1998; 42:929-935
26. Parviainen I, Rantala A, Ruokonen E, et al: Angiotensin converting enzyme inhibition has no effect on blood pressure and splanchnic perfusion after cardiac surgery. J Crit Care 1998; 13:73-80
27. Ajayi AA, Campbell BC, Howie CA, et al: Acute and chronic effects of the converting enzyme inhibitors enalapril and lisinopril on reflex control of heart rate in normotensive man. J Hypertens 1985; 3:47-53
28. Swedberg K, Held P, Kjekshus J, et al: Effects of the early administration of enalapril on mortality in patients with acute myocardial infarction: Results of the Cooperative New Scandinavian Enalapril Survival Study II. N Engl J Med 1992; 327:678-684
29. Boldt J, Schindler E, Wollbrück M, et al: Cardiorespiratory response of intravenous angiotensin-converting enzyme inhibitor enalaprilat in hypertensive cardiac surgery patients. J Cardiothorac Vasc Anaesth 1995; 9:44-49
30. Linas S: Calcium channel blockers versus angiotensin-converting enzyme inhibitors: Renal effects. Am J Kidney Dis 1990; 4(Suppl 1):15-19
31. Ljungman S, Kjekshus J, Swedberg K: Renal function in severe congestive heart failure during treatment with enalapril (the Cooperative North Scandinavian Enalapril Survival Study [CONSENSUS] Trial). Am J Cardiol 1992; 70:479-487
32. Colson P, Ribstein J, Mimran M, et al: Effect of angiotensin converting enzyme inhibition on blood pressure and renal function during open heart surgery. Anesthesiology 1990; 72:23-27
33. Gottlieb SS, Weir MR: Renal effects of angio-tensin converting enzyme inhibition in congestive heart failure. Am J Cardiol 1990; 66:14D-21D
34. Annane D, Bellisant E, Pussard E, et al: Placebo-controlled, randomized, double-blind study of intravenous enalaprilat efficacy and safety in acute cardiogenic pulmonary edema. Circulation 1996; 94:1316-1324
35. Swedberg K, Enerodt P, Kjekshus J, et al: Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality. Circulation 1990; 82:1730-1736
36. Creager MA, Halperin JL, Bernard DB, et al: Acute regional circulatory and renal hemodynamic effects of converting-enzyme inhibition in patients with congestive heart failure. Circulation 1981; 64:483-489
37. Di Carlo L, Chatterjee K, Parmley WW, et al: Enalapril: A new angiotensin-converting enzyme inhibitor in chronic heart failure. J Am Coll Cardiol 1983; 2:865-871