Study of nocturnal sleep and the carryover effects of triazolam and brotizolam using neurophysiological and subjective methods

Neuropsychobiology

Volumn 47, Issue 3, 2003, Pages 158-164

  Suzuki, Hideaki ^a   Yamadera, Hiroshi ^a   Asayama, Kentaro ^a   Kudo, Yoshihisa ^a   Ito, Takao ^a   Tamura, Yoshiatsu ^a   Endo, Shunkichi ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

Brotizolam; Carryover effect; Event related potentials; Healthy subjects; Kwansei Gakuin Sleepiness Scale; Polysomnography; Reaction time; Sleep latency test; Stanford Sleepiness Scale; Triazolam

Indexed keywords

BROTIZOLAM; PLACEBO; TRIAZOLAM;

ADULT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG HALF LIFE; EVENT RELATED POTENTIAL; HUMAN; HUMAN EXPERIMENT; INFORMED CONSENT; LATENT PERIOD; MALE; NEUROPHYSIOLOGY; NIGHT SLEEP; NORMAL HUMAN; POLYSOMNOGRAPHY; PRIORITY JOURNAL; REACTION TIME; RECORDING; REM SLEEP DEPRIVATION; SCALE UP; STATISTICAL SIGNIFICANCE; WAVEFORM;

ADULT; AZEPINES; CIRCADIAN RHYTHM; CROSS-OVER STUDIES; DISORDERS OF EXCESSIVE SOMNOLENCE; DOUBLE-BLIND METHOD; EVOKED POTENTIALS; EYE MOVEMENTS; GABA MODULATORS; HALF-LIFE; HUMANS; HYPNOTICS AND SEDATIVES; MALE; POLYSOMNOGRAPHY; QUESTIONNAIRES; REACTION TIME; SLEEP; TRIAZOLAM;

EID: 0038316677     PISSN: 0302282X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000070586     Document Type: Article

References (23)

1. Hall RCW, Zisook S: Paradoxical reactions to benzodiazepines. Br J Clin Pharmacol 1981;11Suppl 1:99S-104S.
2. Jonas JM, Coleman BS, Sheridan AQ, Kalinske RW: Comparative clinical profiles of triazolam versus other shorter-acting hypnotics. J Clin Psychiatry 1992;53(suppl):19-33.
3. Langley MS, Clissold SP: Brotizolam: A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy as an hypnotic. Drugs 1988;35:104-122.
4. Carskadon MA, Dement WC, Mitler MM, Roth T, Westbrook PR, Keenan S: Guidelines for the multiple sleep latency test (MSLT): A standard measure of sleepiness. Sleep 1986;9:519-524.
5. Hoddes E, Zarcone V, Smythe H, Phillips R, Dement WC: Quantification of sleepiness: A new approach. Psychophysiology 1973;10:431-436.
6. Ishihara K, Saito T, Miyata Y: Sleepiness scale and experimental approach (in Japanese). Shinrigaku Kenkyu 1982;52:362-365.
7. Uchiumi M, Sugiyama T, Suzuki M, Murasaki M: Effects of a single dose of zolpidem, triazolam and nitrazepam on daytime sleepiness (in Japanese). Jpn J Neuropsychopharmacol 1994;16:45-56.
8. Greenblatt DJ, Harmatz JS, Shapiro L, Engelhardt N, Gouthro TA, Shader RI: Sensitivity to triazolam in the elderly. N Engl J Med 1991;324:1691-1698.
9. Bechtel WD: Pharmacokinetics and metabolism of brotizolam in humans. Br J Clin Pharmacol 1983;16Suppl 2:279S-283S.
10. Rechtschaffen A, Kales A: A Manual of Standardized Terminology, Techniques and Scoring System for Sleep Stages of Human Subjects. Washington, USPHS Government Printing Office, 1968.
11. Shimokochi M, Okita H, Satoh K, Shibasaki H, Nakanishi T, Hashimoto I: Official report of the committee on methodology of evoked potential: Japanese Society of EEG and EMG (in Japanese). Jpn J EEG EMG 1985;13:97-104.
12. Kanno O, Sasaki T, Watanabe H, Takazawa S, Nakagome K, Nakajima T, Ichikawa I, Akaho R, Suzuki M: Comparison of the effects of zolpidem and triazolam on nocturnal sleep and sleep latency in the morning: A cross-over study in healthy young volunteers. Prog Neuropsychopharmacol Biol Psychiatry 2000;24:897-910.
13. Carskadon MA, Seidel WF, Greenblatt DJ, Dement WC: Daytime carryover of triazolam and flurazepam in elderly insomniacs. Sleep 1982;5:361-371.
14. Nicholson AN, Stone BM, Pascoe PA: Studies on sleep and performance with a triazolo-1,4-thienodiazepine (brotizolam). Br J Clin Pharmacol 1980;10:75-81.
15. Parrino L, Terzano MG: Polysomnographic effects of hypnotic drugs. Psychopharmacology 1996;126:1-16.
16. Mamelak M, Csima A, Buck L, Price V: A comparative study on the effects of brotizolam and flurazepam on sleep and performance in the elderly. J Clin Psychopharmacol 1989;9:260-267.
17. Thorpy MJ: Report from the American Sleep Disorders Association: The clinical use of the multiple sleep latency test. Sleep 1992;15:268-276.
18. Fujiwara R, Niiyama Y, Sato N, Abe M, Hishikawa Y: Effects of triazolam and flunitrazepam on event-related potentials (ERPs) (in Japanese). Ann Rep Pharmacopsychiatr Res Found 1991;22:34-41.
19. Urata J, Uchiyama M, Iyo M, Enomoto T, Hayakawa T, Tomiyama M, Nakajima T, Sasaki H, Shirakawa S, Wada K, Fukui S, Yamadera H, Okawa M: Effects of a small dose of triazolam on P300 and resting EEG. Psychopharmacology 1996;125:179-184.
20. Hayakawa T, Uchiyama M, Enomoto T, Nakajima T, Kim K, Shibui K, Kudo Y, Ozaki S, Nakajima T, Suzuki H, Urata J, Okawa M: Effects of small dose of brotizolam on P300. Psychiatry Clin Neurosci 2000;54:319-320.
21. Saletu B, Anderer P, Brandstätter N, Frey R, Grünberger J, Klösch G, Mandl M, Wetter T, Zeitlhofer J: Insomnia in generalized anxiety disorder: Polysomnographic, psychometric and clinical investigations before, during and after therapy with a long-versus a short-half-life benzodiazepine (quazepam versus triazolam). Neuropsychobiology 1994;29:69-90.
22. Laurell H, Törnros J: The carry-over effects of triazolam compared with nitrazepam and placebo in acute emergency driving situations and in monotonous simulated driving. Acta Pharmacol Toxicol (Copenh) 1986;58:182-186.
23. Törnros J, Laurell H: Acute and carry-over effects of brotizolam compared to nitrazepam and placebo in monotonous stimulated driving. Pharmacol Toxicol 1990;67:77-80.