Increased susceptibility to Pseudomonas aeruginosa infection under hindlimb-unloading conditions

Journal of Applied Physiology

Volumn 95, Issue 1, 2003, Pages 73-80

  Aviles, Hernan ^a   Belay, Tesfaye ^a   Fountain, Kimberly ^a   Vance, Monique ^a   Sonnenfeld, Gerald ^a  

^a MOREHOUSE SCHOOL OF MEDICINE   (United States)

Author keywords

Antiorthostatic; Spaceflight; Stress

Indexed keywords

CORTICOSTERONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; FEMALE; GRAM NEGATIVE INFECTION; HINDLIMB; IMMUNE SYSTEM; INFECTION SENSITIVITY; LD 50; MOUSE; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SPACE FLIGHT;

EID: 0038309473     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00968.2002     Document Type: Article

References (38)

1. Aviles H and Monroy FP. Immunomodulatory effects of cold stress on mice infected intraperitoneally with a 50% lethal dose of Toxoplasma gondii. Neuroimmunomodulation 9: 6-12, 2001.
2. Banerjee SK, Aviles H, Fox MT, and Monroy FP. Coldstress-induced modulation of cell immunity during acute Toxoplasma gondii infection in mice. J Parasitol 85: 442-447, 1999.
3. Belay T, Aviles H, Vance M, Fountain K, and Sonnenfeld G. Effects of the hindlimb-unloading model of space flight conditions on resistance of mice to infection with Klebsiella pneumoniae. J Allergy Clin Immunol 110: 262-268, 2002.
4. Chapes SK, Mastro AM, Sonnenfeld G, and Berry WD. Antiorthostatic suspension as a model for the effects of space flight on immune system. J Leukoc Biol 54: 227-235, 1993.
5. Christensen NJ, Bratholm P, and Knudsen JH. Lymphocyte norephinephrine and ephinephrine as indices of long-term changes in sympatoadrenal activity in human subjects. J Gravit Physiol 4: 115-116, 1997.
6. Dhabhar FS. Stress-induced enhancement of cell-mediated immunity. Ann NY Acad Sci 840: 359-372, 1998.
7. Dhabhar FS. Acute stress enhances while chronic stress suppresses skin immunity. Ann NY Acad Sci 917: 876-893, 2000.
8. Dhabhar FS. Stress-induced augmentation of immune function - the role of stress hormones, leukocyte trafficking, and cytokines. Brain Behav Immun 16: 785-798, 2002.
9. Dhabhar FS and McEwen BS. Enhancing versus suppressive effects of stress hormones on skin immune function. Proc Natl Acad Sci USA 96: 1059-1064, 1999.
10. Dhabhar FS, Satoskar AR, Bluethmann H, David JR, and McEwen BS. Stress-induced enhancement of skin immune function: a role for gamma interferon. Proc Natl Acad Sci USA 97: 2846-2851, 2000.
11. Durnova GN, Kaplansky AS, and Portuglov VV. Effects of a 22-day space flight on the lymphoid organs of rats. Aviat Space Environ Med 47: 588-591, 1976.
12. Gould CL and Sonnenfeld G. Enhancement of viral pathogenesis in mice maintained in an antiorthostatic suspension model: coordination with effects on interferon production. J Biol Regul Homeost Agents 1: 33-36, 1987.
13. Hawkins WR and Ziegelschmid JF. Clinical aspects of crew health. In: Biomedical Results of Apollo. Washington, DC: NASA, 1975, p. 43-81. (NASA Spec. Rep. SP-368)
14. Ilyan EA and Novikovo VE. A stand for simulation of physiological effects of weightlessness in laboratory experimental rats. Space Biol Med 14: 128-129, 1980.
15. Konstantinova IV, Rykova MP, Lesnyak AT, and Antropova EA. Immune changes during long-duration missions. J Leukoc Biol 54: 189-201, 1993.
16. Kopydlowski KM, McVey DS, Woos KM, Landolo JJ, and Chapes SK. Effects of antiorthostatic suspension and corticosterone on macrophage and spleen cell function. J Leukoc Biol 52: 202-208, 1992.
17. Lyte M and Ernst S. Catecholamine induced growth of gram negative bacteria. Life Sci 50: 203-213, 1992.
18. Mandel AD and Balish E. Effect of space flight on cell mediated immunity. Aviat Space Environ Med 48: 1051-1057, 1976.
19. Miller ES and Sonnenfeld G. Influence of suspension on the expression of protective immunological memory to murine Listeria monocytogenes infection. J Leukoc Biol 54: 378-383, 1993.
20. Miller ES and Sonnenfeld G. Influence of antiorthostatic suspension on resistance to murine Listeria monocytogenes infection. J Leukoc Biol 55: 371-378, 1994.
21. Morey E. Space flight and bone marrow correlation with a new model of weightlessness. Biosience 29: 168-174, 1979.
22. Morey E, Sabelman E, Turner R, and Baylink D. A new rat model simulating some aspects of space flight. Physiologist 22: S23-S24, 1979.
23. Morey-Holton ER and Globus RK. Hindlimb unloading rodent model: technical aspects. J Appl Physiol 92: 1367-1377, 2002.
24. Moynihan JA, Kruszewska B, Brenner GJ, and Cohen N. Neural, endocrine, and immune system interactions. Adv Exp Med Biol 438: 541-549, 1998.
25. Musacchia XJ, Deavers DR, Meininger GA, and Davis TP. A new model for hypokinesia: effects on muscle atrophy in the rat. J Appl Physiol 48: 470-476, 1980.
26. Nickerson CA, Ott CM, Mister SJ, Morroe BJ, Burns-Keliher L, and Pierson DL. Microgravity as a novel environmental signal affecting Salmonella enterica serovar Typhimurium virulence. Infect Immun 68: 3147-3152, 2000.
27. Reed LJ and Muench H. A simple method of estimating fifty percent end points. Am J Hyg 27: 493-497, 1938.
28. Sonnenfeld G, Mandel ED, Konstantinova IV, Berry WD, Taylor GR, Lesnyak AT, Fuchs BB, and Rakhmilevich A. Spaceflight alters immune cell function and distribution. J Appl Physiol 73: 191S-195S, 1993.
29. Sonnenfeld G, Mandel AD, Konstantinova IV, Taylor GR, Berry WD, Welhausen SR, Fuchs B, and Rakhmilevich A. Effects of space flight on levels and activity of immune cells. Aviat Space Environ Med 61: 648-653, 1990.
30. Sonnenfeld G, Morey ER, Williams JA, and Mandel AJ. Effect of a stimulated microgravity model on the production of rat interferon. J Interferon Res 2: 467-470, 1982.
31. Steffen JM and Musacchia XJ. Thymic involution in the suspended rat: adrenal hypertrophy and glucocorticoid receptor content. Aviat Space Environ Med 57: 162-167, 1986.
32. Steffen JM, Robb R, Dambrowski MJ, Musacchia XJ, Mandel AD, and Sonnenfeld G. A suspension for hypokinetin/hypodynamic and antiorthostatic responses in the mouse. Aviat Space Environ Med 55: 612-616, 1984.
33. Taylor GR. Recovery of medically important microorganisms from Apollo astronauts. Aerospace Med 45: 824-828, 1974.
34. Taylor GR and Dardano JR. Human cellular responsiveness following space flight. Aviat Space Environ Med 54, Suppl 1: S55-S59, 1983.
35. Taylor GR, Konstantinova IV, Sonnenfeld G, and Jennings R. Changes in the immune system during and after space flight. Adv Space Biol Med 6: 1-32, 1997.
36. Taylor GR, Neale LS, and Dardano JR. Immunological analysis of U.S. space shuttle crew members. Aviat Space Environ Med 57: 213-217, 1984.
37. th ed.). San Francisco, CA: Addison Wesley Longman, 2001, p. 310.
38. Van Delden C and Iglewski BH. Cell-to-cell signaling and Pseudomonas aeruginosa infections. Emerg Infect Dis 4: 551-560, 1998.