Drosophila Mcm10 interacts with members of the prereplication complex and is required for proper chromosome condensation

Molecular Biology of the Cell

Volumn 14, Issue 6, 2003, Pages 2206-2215

  Christensen, Tim W ^a   Tye, Bik K ^a  

^a Cornell University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; DNA; MINICHROMOSOME MAINTENANCE PROTEIN 2; POTEIN HP1; PROTEIN; PROTEIN CDC45; PROTEIN DUP; PROTEIN MCM10; PROTEIN MCM5; PROTEIN ORC2; PROTEIN ORC5; RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHROMOSOME CONDENSATION; CHROMOSOME REPLICATION; COMPLEX FORMATION; CONTROLLED STUDY; DNA REPLICATION; DROSOPHILA; EMBRYO; GENE DELETION; HETEROCHROMATIN; HUMAN; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN PROTEIN INTERACTION; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY;

ANIMALS; CELL CYCLE; CELL CYCLE PROTEINS; CHROMOSOMES; DNA REPLICATION; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; FUNGAL PROTEINS; ORIGIN RECOGNITION COMPLEX; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

ANIMALIA; ARACHNIDA; DROSOPHILA MELANOGASTER; HEXAPODA; MELANOGASTER; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0038308585     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E02-11-0706     Document Type: Article

References (43)

1. Alani, E., Cao, L., and Kleckner, N. (1987). A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains. Genetics 116, 541-545.
2. Austin, R.J., Orr-Weaver, T.L., and Bell, S.P. (1999). Drosophila ORC specifically binds to ACE3, an origin of DNA replication control element. Genes Dev. 13, 2639-2649.
3. Bell, S.P. (2002). The origin recognition complex: from simple origins to complex functions. Genes Dev. 16, 659-672.
4. Bell, S.P., and Dutta, A. (2002). DNA replication in eukaryotic cells. Annu. Rev. Biochem. 71, 333-374.
5. Blow, J.J., and Laskey, R.A. (1988). A role for the nuclear envelope in controlling DNA replication within the cell cycle. Nature 332, 546-548.
6. Burke, T.W., Cook, J.G., Asano, M., and Nevins, J.R. (2001). Replication factors mcm2 and orc1 interact with the histone acetyltransferase hbo1. J. Biol. Chem. 276, 15397-15408.
7. Campbell, J.L., and Newlon, C.S. (1991). Chromosomal DNA replication. In: The Molecular and Cellular Biology of the Yeast Saccharomyces: Genome Dynamics, Protein Synthesis, and Energetics, ed. J.R. Broach, J.R. Pringle, and E.W. Jones, Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
8. Chesnokov, I., Remus, D., and Botchan, M. (2001). Functional analysis of mutant and wild-type Drosophila origin recognition complex. Proc. Natl. Acad. Sci. USA 98, 11997-12002.
9. Clemens, J.C., Worby, C.A., Simonson-Leff, N., Muda, M., Maehama, T., Hemmings, B.A., and Dixon, J.E. (2000). Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways. Proc. Natl. Acad. Sci. USA 97, 6499-6503.
10. Dhar, S.K., Yoshida, K., Machida, Y., Khaira, P., Chaudhuri, B., Wohlschlegel, J.A., Leffak, M., Yates, J., and Dutta, A. (2001). Replication from oriP of Epstein-Barr virus requires human ORC and is inhibited by geminin. Cell 106, 287-296.
11. Dobie, K.W., Kennedy, C.D., Velasco, V.M., McGrath, T.L., Weko, J., Patterson, R., and Karpen, G.H. (2001). Identification of chromosome inheritance modifiers in Drosophila melanogaster. Genetics 157, 1623-1637.
12. Ehrenhofer-Murray, A.E., Gossen, M., Pak, D.T.S., Botchan, M.R., and Rine, J. (1995). Separation of origin recognition complex functions by cross-species complementation. Science 270, 1671-1674.
13. Ehrenhofer-Murray, A.E., Kamakaka, R.T., and Rine, J. (1999). A role for the replication proteins PCNA, RF-C, polymerase e and Cdc45 in transcriptional silencing in Saccharomyces cerevisiae. Genetics 153, 1171-1182.
14. Eissenberg, J.C., and Elgin, S.C. (2000). The HP1 protein family: getting a grip on chromatin. Curr. Opin. Genet. Dev. 10, 204-210.
15. Findeisen, M., El-Denary, M., Kapitza, T., Graf, R., and Strausfeld, U. (1999). Cyclin A-dependent kinase activity affects chromatin binding of ORC, Cdc6, and MCM in egg extracts of Xenopus laevis. Eur. J. Biochem. 264, 415-426.
16. Gerbi, S., and Bielinsky, A. (2002). DNA replication and chromatin. Curr. Opin. Genet. Dev. 12, 243-248.
17. Goto, A., Aoki, M., Ichihara, S., and Kitagawa, Y. (2001). α-, β- or γ-chain-specific RNA interference of laminin assembly in Drosophila Kc167 cells. Biochem. J. 360, 167-172.
18. Hearst, J., Kauffman, L., and McClain, W. (1998). A simple mechanism for the avoidance of entanglement during chromosome replication. Trends Genet. 14, 244-247.
19. Hofmann, J.F., and Beach, D. (1994). cdt1 is an essential target of the Cdc10/Sct1 transcription factor: requirement for DNA replication and inhibition of mitosis. EMBO J. 13, 425-434.
20. Homesley, L., Lei, M., Kawasaki, Y., Sawyer, S., Christensen, T., and Tye, B.K. (2000). Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins. Genes Dev. 14, 913-926.
21. Hua, X.H., and Newport, J. (1998). Identification of a preinitiation step in DNA replication that is independent of origin recognition complex and Cdc6, bur dependent on cdk2. J. Cell Biol. 140, 271-281.
22. Hutvagner, G., and Zamore, P. (2002). RNAi: nature abhors a double-strand. Curr. Opin. Genet. Dev. 12, 225-232.
23. Izumi, M., Yanagi, K., Mizuno, T., Yokoi, M., Kawasaki, Y., Moon, K.-Y., Hurwitz, J., and Hanaoka, F. (2000). Identification of the human homolog of Saccharomyces cerevisiae Mcm10, a critical component for the initiation of DNA synthesis. Nucleic Acids Res. 28, 4769-4777.
24. Izumi, M., Yatagai, F., and Hanaoka, F. (2001). Cell cycle-dependent proteolysis and phosphorylation of human Mcm10. J. Biol. Chem. 276, 48526-48531.
25. Kawasaki, Y., Hiraga, S., and Sugino, A. (2000). Interactions between Mcm10p and other replication factors are required for proper initiation and elongation of chromosomal DNA replication in Saccharomyces cerevisiae. Genes Cells 5, 975-989.
26. Landis, G., Kelley, R., Spradling, A., and Tower, J. (1997). The k43 gene, required for chorion gene amplification and diploid cell chromosome replication, encodes the Drosophila homolog of yeast origin recognition complex subunit 2. Proc. Natl. Acad. Sci. USA 94, 3888-3892.
27. Lei, M., and Tye, B.K. (2001). Initiating DNA synthesis: from recruiting to activating the MCM complex. J. Cell Sci. 114, 1447-1454.
28. Loebel, D., Huikeshoven, H., and Cotterill, S. (2000). Localisation of the DmCdc45 DNA replication factor in the mitotic cycle and during chorion gene amplification. Nucleic Acids Res. 28, 3897-3903.
29. Loupart, M.L., Krause, S.A., and Heck, M.S. (2000). Aberrant replication timing induces defective chromosome condensation in Drosophila ORC2 mutants. Curr. Biol. 10, 1547
30. Maiorano, D., Moreau, J., and Mechali, M. (2000). XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis. Nature 404, 622-625.
31. Merchant, A.M., Kawasaki, Y., Chen, Y., Lei, M., and Tye, B.K. (1997). A lesion in the DNA replication initiation factor Mcm10 induces pausing of elongation forks through chromosomal replication origins in S. cerevisiae. Mol. Cell. Biol. 17, 3261-3271.
32. Mihaylov, I.S., Kondo, T., Jones, L., Ryzhikov, S., Tanaka, J., Zheng, J., Higa, L.A., Minamino, N., Cooley, L., and Zhang, H. (2002). Control of DNA replication and chromosome ploidy by geminin and cyclin A. Mol. Cell. Biol. 22, 1868-1880.
33. Pak, T.S.D., Pflumm, M., Chesnokov, I., Huang, D.W., Kellum, R., Marr, J., Romanowski, P., and Botchan, M.R. (1997). Association of the origin recognition complex with heterochromatin and HP1 in higher eukaryotes. Cell 91, 311-323.
34. Pflumm, M.F., and Botchan, M.R. (2001). Orc mutants arrest in metaphase with abnormally condensed chromosomes. Development 128, 1697-1707.
35. Raghuraman, M.K., Winzeler, E.A., Collingwood, D., Hunt, S., Wodicka, L., Conway, A., Lockhart, D.J., Davis, R.W., Brewer, B.J., and Fangman, W.L. (2001). Replication dynamics of the yeast genome. Science 294, 115-121.
36. Rao, P.N., and Johnson, R.T. (1970). Mammalian cell fusion: studies on the regulation of DNA synthesis and mitosis. Nature 225, 159-164.
37. Solomon, N.A., Wright, M.B., Chang, S., Buckley, A.M., Dumas, L.B., and Gaber, R.F. (1992). Genetic and molecular analysis of DNA43 and DNA52: two new cell-cycle genes in Saccharomyces cerevisiae. Yeast 8, 273-289.
38. Stuurman, N., Sasse, B., and Fisher, P.A. (1996). Intermediate filament protein polymerization: molecular analysis of Drosophila nuclear lamin head-to-tail binding. J. Struct. Biol. 117, 1-15.
39. Tye, B.K. (2000). Insights into DNA replication from the third domain of life. Proc. Natl. Acad. Sci. USA 97, 2399-2401.
40. Whittaker, A.J., Royzman, I., and Orr-Weaver, T.L. (2000). Drosophila double parked: a conserved, essential replication protein that colocalizes with the origin recognition complex and links DNA replication with mitosis and the down-regulation of S phase transcripts. Genes Dev. 14, 1765-1776.
41. Wohlschlegel, J.A., Dhar, S.K., Prokhorova, T.A., Dutta, A., and Walter, J.C. (2002). Xenopus Mcm10 binds to origins of DNA replication after Mcm2-7 and stimulates origin binding of Cdc45. Mol. Cell 9, 1-20.
42. Wohlschlegel, J.A., Dwyer, B.T., Dhar, S.K., Cvetic, C., Walter, J.C., and Dutta, A. (2001). Geminin inhibits eukaryotic DNA replication by binding to Cdt1. Science 290, 2309-2312.
43. Wyrick, J.J., Aparicio, J.G., Chen, T., Barnett, J.D., Jennings, E.G., Young, R.A., Bell, S.P., and Aparicio, O.M. (2001). Genome-wide distribution of ORC and MCM proteins in S. cerevisiae: high-resolution mapping of replication origins. Science 294, 2357-2360.