Nitric oxide synthase gene polymorphisms and diabetic nephropathy

Diabetologia

Volumn 46, Issue 3, 2003, Pages 426-428

  Rippin, J D ^a   Patel, A ^a   Belyaev, N D ^a   Gill, G V ^b   Barnett, A H ^a   Bain, S C ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY HOSPITAL AINTREE   (United Kingdom)

Author keywords

Case control studies; Chronic *etiology; Diabetes mellitus; Diabetic nephropathy *genetics; Endothelium; Human; Kidney failure; Nitric oxide *genetics; Nitric oxide synthase; Polymorphism (Genetics); Type 1 *genetics

Indexed keywords

AGAROSE; INSULIN; NITRIC OXIDE SYNTHASE;

ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DISEASE ASSOCIATION; DNA POLYMORPHISM; DYSLIPIDEMIA; FLUORESCENCE; GENE FREQUENCY; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; HYPERTENSION; INSULIN DEPENDENT DIABETES MELLITUS; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SMOKING;

EID: 0038303081     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-003-1046-3     Document Type: Article

References (9)

1. Borch-Johnsen K, Andersen PK, Deckert T (1995) The effect of proteinuria on relative mortality in type 1 (insulin-dependent) diabetes mellitus. Diabetologia 28:590-596
2. Yamada K, Nakano H, Nakayama M et al. (1995) Endothelium-dependent relaxation in peripheral vasculature and kidney of non-insulin-dependent diabetes mellitus. J Diabetes Complications 9:203-207
3. Tsukada T, Yokoyama K, Arai T, et al. (1998) Evidence of association of the ecNOS gene polymorphism with plasma NO metabolite levels in humans. Biochem Biophys Res Commun 245:190-193
4. Chowdhury TA, et al. (1996) Examination of two genetic polymorphisms within the renin-angiotensin system: no evidence for an association with nephropathy in IDDM. Diabetologia 39:1108-1104
5. Wang XL, Sim AS, Badenhoop RF, McCredie RM, Wilcken DE (1996) A smoking-dependent risk of coronary artery disease associated with a polymorphism of the endothelial nitric oxide synthase gene. Nat Med 2:41-45
6. Glenn CL, Wang WY, Morris BJ (1999) Different frequencies of inducible nitric oxide synthase genotypes in older hypertensives. Hypertension 33:927-932
7. Johannesen J, Tarnow L, Parving HH, Nerup J, Pociot F (2000) CCTTT-repeat polymorphism in the human NOS2-promoter confers low risk of diabetic nephropathy in type 1 diabetic patients. Diabetes Care 23:560-562
8. Rippin JD, Patel A, Bain SC (2001) Genetics of diabetic nephropathy. Best Pract Res Clin Endocrinol Metab 15:345-358
9. Gilbert RE, Cooper ME, McNally PG, O'Brien RC, Taft J, Jerums G (1994) Microalbuminuria: prognostic and therapeutic implications in diabetes mellitus. Diabet Med. 11:636-645