Biopterin metabolism in patients with malignant syndrome

Parkinsonism and Related Disorders

Volumn 9, Issue SUPPL. 1, 2003, Pages 11-14

  Ichinose, Hiroshi ^a   Ohye, Tamae ^a   Shinotoh, Hitoshi ^b   Arai, Kimihito ^c   Yamazaki, Shunzo ^d   Mizuta, Eiji ^d   Kuno, Sadako ^d   Nagatsu, Toshiharu ^a  

^a FUJITA HEALTH UNIVERSITY   (Japan)

^b Asahi Neurological Hospital   (Japan)

^c CHIBA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d UTANO NATIONAL HOSPITAL   (Japan)

Author keywords

Dopamine; GTP Cyclohydrolase I; Neopterin; Tetrahydrobiopterin

Indexed keywords

BIOPTERIN; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; NEOPTERIN;

ADULT; AGED; ARTICLE; AUTOPSY; BRAIN LEVEL; BRAIN REGION; CASE REPORT; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN TISSUE; HYPOTHALAMUS; NEUROLEPTIC MALIGNANT SYNDROME; PARKINSON DISEASE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; VITAMIN METABOLISM;

EID: 0038300205     PISSN: 13538020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1353-8020(02)00120-7     Document Type: Article

References (15)

1. Friedman J.H., Feinberg S.S., Feldman R.G. A neuroleptic malignant-like syndrome due to levodopa therapy withdrawal. JAMA. 254:1985;2792-2795.
2. Figa-Talamanca L., Gualandi C., DiMeo L., et al. Hyperthermia after discontinuance of levodopa and bromocriptine therapy: impaired dopamine receptors a possible cause. Neurology. 35:1985;258-261.
3. Simpson D.M., Davis G.C. Case report of neuroleptic malignant syndrome associated with withdrawal from amantadine. Am J Psychiatry. 141:1984;796-797.
4. Nichol C.A., Smith G.K., Duch D.S. Biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin. Annu Rev Biochem. 54:1985;729-764.
5. Segawa M., Hosaka A., Miyagawa F. Hereditary progressive dystonia with marked diurnal fluctuation. Adv Neurol. 14:1976.
6. Nygaard T.G., Marsden C.D., Duvoisin R.C. Dopa-responsive dystonia. Adv Neurol. 50:1988;377-384.
7. Ichinose H., Ohye T., Takahashi E., Seki N., et al. Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene. Nature Genet. 8:1994;236-242.
8. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal Biochem. 72:1976;248-254.
9. Nagatsu T., Horikoshi T., Sawada M., et al. Biosynthesis of tetrahydrobiopterin in parkinsonian human brain. Adv Neurol. 45:1986;223-226.
10. Fujishiro K., Hagihara M., Takahashi A., et al. Concentrations of neopterin and biopterin in the cerebrospinal fluid of patients with Parkinson's disease. Biochem Med Metab Biol. 44:1990;97-100.
11. Nagatsu T., Levitt M., Udenfriend S. Tyrosine hydroxylase: the initial step in norepinephrine biosynthesis. J Biol Chem. 239:1964;2910-2917.
12. Nishijima K., Ishiguro T. Cerebrospinal fluid levels of monoamine metabolites and gamma-aminobutyric acid in neuroleptic malignant syndrome. J Psychiat Res. 29:1995;233-244.
13. Kish S.J., Kleinert R., Minauf M., et al. Brain neurotransmitter changes in three patients who had a fatal hyperthermia syndrome. Am J Psychiatry. 147:1990;1358-1363.
14. Granato J.E., Stern B.J., Ringel A., et al. Neuroleptic malignant syndrome: successful treatment with dantrolene and bromocriptine. Ann Neurol. 14:1983;89-90.
15. Gurrera R.J. Sympathoadrenal hyperactivity and the etiology of neuroleptic malignant syndrome. Am J Psychiatry. 156:1999;169-180.