Molecular adaptation to hibernation: The hemoglobin of Dryomys nitedula

Pflugers Archiv European Journal of Physiology

Volumn 446, Issue 1, 2003, Pages 46-51

  Clementi, M E ^a   Petruzzelli, R ^b   Filippucci, M G ^c   Capo, C ^c   Misiti, F ^a   Giardina, B ^a  

^a CATHOLIC UNIVERSITY   (Italy)

^b UNIVERSITY OF CHIETI   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Dwomys nitedula; Hemoglobin; Hibernation

Indexed keywords

CARBON DIOXIDE; CHLORIDE ION; GLYCERIC ACID; ORGANOPHOSPHATE;

ADAPTATION; ALPHA CHAIN; ANIMAL EXPERIMENT; APNEA; ARTICLE; BETA CHAIN; BODY TEMPERATURE; HEMOGLOBIN DETERMINATION; HIBERNATION; MOUSE; NONHUMAN; OXYGEN AFFINITY; OXYGEN TRANSPORT; OXYGENATION; PH; PRIORITY JOURNAL; TEMPERATURE SENSITIVITY;

EID: 0038298708     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00424-002-0960-4     Document Type: Article

References (25)

1. Atha DH, Ackers GK (1974) Calorimetric determination of the heat of oxygenation of human hemoglobin as a function of pH and the extent of reaction. Biochemistry 13:2376-2383
2. Basset P, Beuzard Y, Garel MC, Rosa J (1978) Isoelectric focusing of human hemoglobins. Blood 51:971-982
3. Brix O, Bardgard A, Mathisen S, Tyler N, Nuutinen M, Condo SG, Giardina B (1990) Oxygen transport in the blood of arctic mammals: adaptation to local heterothermia. J Comp Physiol [B] 159:655-660
4. Burlington RF, Whitten BK (1971) Red cell 2,3-diphosphoglycerate in hibernating ground squirrels. Comp Biochem Physiol A 38:469-471
5. Clementi ME, Condò SG, Castagnola M, Giardina B (1994) Hemoglobin function under extreme life conditions. Eur J Biochem 223:309-317
6. Coletta M, Clementi ME, Ascenzi P, Petruzzelli R, Condò SG, Giardina B (1992) A comparative study of the temperature dependence of the oxygen-binding properties of mammalian hemoglobins. Eur J Biochem 204:1155-1157
7. Condo SG, Giardina B, Barra D, Gill SJ, Brunori M (1981) Purification and functional properties of the hemoglobin components from the rat (Wistar). Eur J Biochem 116:243-247
8. Di Prisco G, Condò SG, Tamburrini M, Giardina B (1991) Oxygen transport in extreme environments. Trends Biochem Sci 16:471-474
9. Doherty JC, Kronon MT, Rotermund AJ (1993) The effects of short term cold storage upon ATP and 2,3-BPG levels in the blood of euthermic and hibernating thirteen-lined ground squirrels Spermophilus tridecemlineatus. Comp Biochem Physiol A 104:87-91
10. Duffy LK, Genaux CT, Florant GL (1986) A reinvestigation of hemoglobin alterations in ground squirrels while in various hibernation activity states. Comp Biochem Physiol B 83:797-800
11. Giardina B, Amiconi G (1981) Measurement of binding of gaseous and nongaseous ligands to hemoglobin by conventional spectrophotometric procedures. Methods Enzymol 76:417-427
12. Giardina B, Condò SG, Petruzzelli R, Bardgard A, Brix O (1990) Thermodynamics of oxygen binding to arctic hemoglobins. The case of reindeer. Biophys Chem 37:281-286
13. Johansen K, Lykkeboe G, Weber RE, Maloiy GM (1976) Blood respiratory properties in the naked mole rat Heterocephalus glaber, a mammal of low body temperature. Respir Physiol 28:303-314
14. Kleinschmidt T, Sgouros JG (1987) Hemoglobin sequences. Biol Chem Hoppe-Seyler 368:579-615
15. Kramm C, Sattrup G, Baumann R, Bartels H (1975) Respiratory function of blood in hibernating and non-hibernating hedge-hogs. Respir Physiol 25:311-318
16. 2 concentrationss in burrows of euthermic and hibernating golden hamster. Comp Biochem Physiol A 85:517-522
17. Maginniss LA, Milson WK (1994) Effects of hibernation on blood oxygen transport in the golden-mantled ground squirrel. Respir Physiol 95:195-208
18. 2 affinity at 6 and 38°C. Am J Physiol 221:128-130
19. Pulawa LK, Florant GL (2000) The effects of caloric restriction on the body composition and hibernation of the golden-mantled ground squirrel (Spermophilus lateralis). Physiol Biochem Zool 73:538-546
20. Reese SA, Crocker CE, Carwile ME, Jackson DC, Ultsch GR (2001) The physiology of hibernation in common map turtles (Graptemys geographica). Comp Biochem Physiol A 130:331-340
21. Reese SA, Crocker CE, Jackson DC, Ultsch GR (2001) The physiology of hibernation among painted turtles: the midland painted turtle (Chrysemys picta marginata). Respir Physiol 124:43-50
22. Tempel GE, Musacchia XJ (1975) Erythrocyte 2,3-diphospho-glycerate concentrations in hibernating, hypothermic and rewarming hamsters. Proc Soc Exp Biol Med 148:588-592
23. Toien O, Drew KL, Chao ML, Rice ME (2001) Ascorbate dynamics and oxygen consumption during arousal from hibernation in Arctic ground squirrels. Am J Physiol 281:R572-583
24. Van Breukelen F, Martin SL (2002) Molecular adaptations in mammalian hibernators: unique adaptations or generalized responses? J Appl Physiol 92:2640-2647
25. Wells RM (1999) Evolution of haemoglobin function: molecular adaptations to environment. Clin Exp Pharmacol Physiol 26:591-595