Th1 and Th2 cytokine production among asthmatic children after immunotherapy

Journal of Asthma

Volumn 40, Issue 3, 2003, Pages 273-279

  Huang, Jing Long ^a   Chen, Li Chen ^a   Yeh, Kuo Wei ^a   Lin, Syh Jae ^a   Hsieh, Kue Hsiung ^a   Kuo, Ming Ling ^b,c  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^c CHANG GUNG CHILDREN S HOSPITAL   (Taiwan)

Author keywords

Asthma; Cytokines; Immunotherapy; T helper cells

Indexed keywords

CD4 ANTIGEN; CYTOKINE;

ALLERGIC ASTHMA; ARTICLE; CHILD; CHILDHOOD DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DESENSITIZATION; HUMAN; IMMUNOTHERAPY; LYMPHOCYTE COUNT; MITE; MONONUCLEAR CELL; STAINING; TH1 CELL; TH2 CELL; TREATMENT OUTCOME;

ALLERGENS; ASTHMA; CASE-CONTROL STUDIES; CHILD; CYTOKINES; HUMANS; IMMUNOTHERAPY; LEUKOCYTES, MONONUCLEAR; PYROGLYPHIDAE; TH1 CELLS; TH2 CELLS;

EID: 0038285603     PISSN: 02770903     EISSN: None     Source Type: Journal    
DOI: 10.1081/JAS-120018325     Document Type: Article

References (27)

1. Noon L. Prophylactic inoculation against hay fever. Lancet 1911; 1:1572-1573.
2. Aas K. Hyposensitization in house dust allergy asthma: a double-blind controlled study. Acta Paediatrica Scandinavica 1971; 60(3):264-268.
3. Warner JO, Price JF, Soothill JF, Hey EN. Controlled trial of hyposensitization to Dermatophagoides pteronyssinus in children with asthma. Lancet 1978; 2(8096):912-915.
4. Bousquet J, Calvayrac P, Guerin B, Hejjaoui A, Dhivert H, Hewitt B, Michel FB. Immunotherapy with a standardized Dermatophagoides pteronyssinus extract. I: in vivo and in vitro parameters after a short course of treatment. J Allergy Clin Immunol 1985; 76(5):734-744.
5. Adkinsan NF, Eggleston PA, Eney D, Goldstein EO, Schuberth KC, Bacon JR, Hamilton RG, Weiss ME, Arshad H, Meinert CL, Tonascia J, Wheeler B. A controlled trial of immunotherapy for asthma in allergic children. N Engl J Med 1997; 336(5):324-331.
6. Weber RW. Immunotherapy with allergens. JAMA 1997; 278(22):1881-1887.
7. Djukanovic R, Roche WR, Wilson JW, Beasley CR, Twentyman OP, Howarth RH, Holgate ST. Mucosal inflammation in asthma. Am Rev Respir Dis 1990; 142(2):434-457.
8. Romagnani S. Regulation and deregulation of human IgE synthesis. Immunol Today 1990; 11(9):316-321.
9. Sutton BJ, Gould HJ. The human IgE network. Nature 1993; 366(6454):421-428.
10. Sedgwick JB, Calhoun WJ, Gleich GJ, Kita H, Abrams JS, Schwartz LB, Volovitz B, Ben-Yaakov M, Busse WW. Immediate and late airway response of allergic rhinitis patients to segmental antigen challenge. Am Rev Respir Dis 1991; 144(6):1274-1278.
11. Parronchi P, Macchia D, Piccinni MP, Biswas P, Simonelli C, Maggi E, Ricci M, Ansari AA, Romagnani S. Allergen and bacterial antigen-specific T-cell clones established from atopic donors show a different profile of cytokine production. Proc Natl Acad Sci USA 1991; 88(10):4538-4542.
12. Simon HU, Yousefi S, Schranz C, Schapowal A, Bachert C, Blaser K. Direct demonstration of delayed eosinophil apoptosis as a mechanism causing tissue eosinophilia. J Immunol 1997; 158(8):3902-3908.
13. Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL. Two types of murine helper T cell clones. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986; 136(7):2348-2357.
14. Romagnai S. Human Th1 and Th2 subsets: regulation of differentiation and role in protection and immunopathology. Int Arch Allergy Appl Immunol 1992; 98(4):279-285.
15. Péne J, Rousset F, Briére F, Chretien I, Bonnefoy JY, Spits H, Yokota T, Arai N, Arai K, Banchereau J. IgE production by normal human lymphocytes is induced by interleukin-4 and suppressed by interferons γ and α and prostaglandin E2. Proc Natl Acad Sci USA 1988; 85(18):6880-6884.
16. Del Prete G, Maggi E, Parronchi P, Chretien I, Tiri A, Macchia D, Ricci M, Banchereau J, De Vries J, Romagnani S. IL-4 is an essential factor for the IgE synthesis induced in vitro by human T cell clones and their supernatants. J Immunol 1988; 140(12):4193-4198.
17. Perez VL, Lederer JA, Lichtman AH, Abbas AK. Stability of Th1 and Th2 populations. Internal Immunol 1995; 7(5):869-875.
18. Robinson DS, Hamid Q, Ying S, Tsicopoulos A, Barkans J, Bentley AM, Corrigan C, Durham SR, Kay AB. Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma. N Engl J Med 1992; 326(5):298-304.
19. Van Bever HP, Vereecke IF, Bridts CH, De Clerck LS, Stevens WJ. Comparison between the in vitro cytokine production of mononuclear cells of young asthmatics with and without immunotherapy (IT). Clin Exp Allergy 1998; 28(8):943-949.
20. O'Brien RM, Xu H, Rolland JM, Byron KA, Thomas WR. Allergen-specific production of interferon-γ by peripheral blood mononuclear cells and CD8 T cells in allergic disease and following immunotherapy. Clin Exp Allergy 2000; 30(3):333-340.
21. Majori M, Caminati A, Corradi M, Brianti E, Scarpa S, Pesci A. T-cell cytokine pattern at three time points during specific immunotherapy for mite-sensitive asthma. Clin Exp Allergy 2000; 30(3):341-347.
22. Nakada S, Ito K, Urata C, Sakamoto Y, Hasegawa M, Nakagawa T, Miyamoto T. Allergenicity and immunogenicity of house-dust mite (Dermatophagoides farinae) antigens treated with flutaraldehyde. Ann Allergy 1985; 54(5):437-441.
23. Kuo ML, Huang JL, Yeh KW, Li PS, Hsieh KH. Evaluation of Th1/Th2 ratio and cytokine production profile during acute exacerbation and convalescence in asthmatic children. Ann Allergy Asthma Immunol 2001; 86(3):272-276.
24. Krug N, Madden J, Redington AE, Lackie P, Djukanovic R, Schauer U, Holgate ST, Frew AJ, Howarth PH. T-Cell cytokine profile evaluated at the single cell level in BAL and blood in allergic asthma. Am J Respir Cell Mol Biol 1996; 14(4):319-326.
25. Walker C, Bode E, Boer L, Hansel TT, Blaser K, Virchow JC Jr. Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage. Am Rev Respir Dis 1992; 146(1):109-115.
26. Movérare R, Elfman L, Bjornsson E, Stalenheim G. Cytokine production by peripheral blood mononuclear cells following birch-pollen immunotherapy. Immunol Letter 2000; 73(1):51-56.
27. Hedlin G. The role of immunotherapy in pediatric allergic disease. Curr Opion Pediatr 1995; 7(6):676-682.