Molecular size distribution analysis of human gingival glycosaminoglycans in cyclosporin- and nifedipine-induced overgrowths

Journal of Periodontal Research

Volumn 38, Issue 2, 2003, Pages 182-189

  Martins, Rita C L ^a   Werneck, Claudio C ^a   Rocha, Lia A G ^a   Feres Filho, Eduardo J ^a   Silva, Luiz Claudio F ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Gingiva; Gingival overgrowth; Glycosaminoglycans; Periodontal disease

Indexed keywords

CHONDROITIN SULFATE; CYCLOSPORIN A; DERMATAN SULFATE; GLYCOSAMINOGLYCAN; GLYCOSAMINOGLYCAN POLYSULFATE; HEPARAN SULFATE; HYALURONIC ACID; NIFEDIPINE; CALCIUM CHANNEL BLOCKING AGENT; CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT; SEPHAROSE; SUPEROSE 6B;

ADOLESCENT; ADULT; AGAR GEL ELECTROPHORESIS; ARTICLE; CASE REPORT; CHEMICAL COMPOSITION; CONTROLLED STUDY; GEL FILTRATION CHROMATOGRAPHY; GINGIVA; GINGIVA OVERGROWTH; HUMAN; HUMAN TISSUE; MOLECULAR SIZE; POLYACRYLAMIDE GEL ELECTROPHORESIS; SIDE EFFECT; CHEMICAL STRUCTURE; CHEMISTRY; GEL CHROMATOGRAPHY; ISOLATION AND PURIFICATION; METABOLISM; MIDDLE AGED; MOLECULAR WEIGHT;

ADOLESCENT; ADULT; CALCIUM CHANNEL BLOCKERS; CHONDROITIN SULFATES; CHROMATOGRAPHY, GEL; CYCLOSPORINE; DERMATAN SULFATE; ELECTROPHORESIS, AGAR GEL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GINGIVA; GINGIVAL OVERGROWTH; GLYCOSAMINOGLYCANS; HEPARITIN SULFATE; HUMANS; HYALURONIC ACID; IMMUNOSUPPRESSIVE AGENTS; MIDDLE AGED; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; NIFEDIPINE; SEPHAROSE;

EID: 0038283171     PISSN: 00223484     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0765.2003.02004.x     Document Type: Article

References (22)

1. Seymour RA, Thomason JM, Ellis JS. The pathogenesis of drug-induced gingival overgrowth. J Clin Periodontol 1996;23: 165-175.
2. Rees TD. Drugs and oral disorders. Periodontol 2000 1998;18:21-36.
3. Mariani G, Calastrini C, Carinci F, Bergamini L, Calastrini F, Stabellini G. Ultrastructural and histochemical features of the ground substance in cyclosporin A-induced gingival overgrowth. J Periodontol 1996;67:21-27.
4. 3H-glucosamine by fibroblast populations exposed to cyclosporine. J Periodontol 1994;65:565-567.
5. Newell J, Irwin CR. Comparative effects of cyclosporin on glycosaminoglycan synthesis by gingival fibroblasts. J Periodontol 1997;68:443-447.
6. Rocha LAG, Martins RCL, Werneck CC, Feres-Filho EJ, Silva LCF. Human gingival glycosaminoglycans in cyclosporin-induced overgrowth. J Periodont Res 2000;35:158-164.
7. Dahllof G, Modeer T, Reinholt FP, Wikstrom B, Hjerpe A. Proteoglycans and glycosaminoglycans in phenytoin-induced gingival overgrowth. J Periodont Res 1986;21:13-21.
8. Suresh R, Puvanakrishnan R, Dhar SC. Alterations in human gingival glycosaminoglycan pattern in inflammation and in phenytoin induced overgrowth. Mol Cell Biochem 1992;115:149-154.
9. Cardoso LEM, Mourão PAS. Glycosaminoglycan fractions from human arteries presenting diverse susceptibilities to atherosclerosis have different binding affinities to plasma LDL. Arterioscler Thromb 1994;14:115-124.
10. Martins RCL, Lima FRS, Werneck CC, Moura-Neto V, Silva LCF. Patterns of synthesis and secretion of sulfated glycosaminoglycans in primary cortical and cerebellar astrocytes in vitro. Biol Cell 2000;92:421-427.
11. Saito N, Yamagata T, Suzuki S. Enzymatic methods for the determination of small quantities of isomeric chondroitin sulfates. J Biol Chem 1968;243:1536-1544.
12. Shively JE, Conrad HE. Formation of anhydrosugars in the chemical depolymerization of heparin. Biochemistry 1976;15:3932-3942.
13. Farndale RW, Buttle DJ, Barret AJ. Improved quantitation and discrimination of sulfated glycosaminoglycans by use of dimethylmethylene blue. Biochim Biophys Acta 1986;883:173-177.
14. Dische ZA. A new specific color reaction of hexuronic acids. J Biol Chem 1947;167:189-198.
15. 2+-ATPase. Glycobiology 2000;10:773-779.
16. Bartold PM. Proteoglycans of the periodontium: structure, role and function. J Periodont Res 1987;22:431-444.
17. Bartold PM, Wiebkin OW, Thonard JC. Molecular weight estimation of sulphated glycosaminoglycans in human gingivae. Connect Tiss Res 1982;9:165-172.
18. Bartold PM, Wiebkin OW, Thonard JC. Behaviour of hyaluronic acid from gingival epithelium and connective tissue in the analytical ultracentrifuge. Connect Tiss Res 1984;12:257-264.
19. Bartold PM, Page RC. The effect of chronic inflammation on gingival tissue preoteoglycans and hyaluronic acid. J Oral Pathol 1986;15:367-374.
20. Embery G, Oliver WM, Stanbury JB. The metabolism of proteoglycans and glycosaminoglycans in inflamed human gingiva. J Periodont Res 1979;14:512-519.
21. Purvis JA, Embery G, Oliver JM. Molecular size distribution of proteoglycans in human inflamed gingival tissue. Arch Oral Biol 1984;29:513-519.
22. Yamalik N, Kilinc K, Caglayan F, Eratalay K, Caglayan G. Molecular size distribution analysis of human gingival proteoglycans and glycosaminoglycans in specific periodontal diseases. J Clin Periodontol 1998;25:145-152.