Attitudes towards genetic screening for predisposition to colon cancer among cancer patients, their relatives and members of the community: Results of focus group interviews

Community Genetics

Volumn 6, Issue 1, 2003, Pages 29-36

  Ramsey, Scott D ^a,c   Wilson, Susan ^a   Spencer, Anna ^a   Geidzinska, Antoinette ^b   Newcomb, Polly ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c Fred Hutchinson Cancer Research Center   (United States)

Author keywords

Focus group; Hereditary colorectal cancer; Testing, barriers

Indexed keywords

ADULT; ARTICLE; CANCER PATIENT; CANCER SCREENING; CANCER SUSCEPTIBILITY; CLINICAL ARTICLE; COLON CANCER; COMMUNITY; CONTROLLED STUDY; FAMILIAL CANCER; FEMALE; GENE MUTATION; GENETIC ANALYSIS; GENETIC SCREENING; HIGH RISK POPULATION; HUMAN; INSURANCE; MALE; PRIORITY JOURNAL; RELATIVE;

EMPIRICAL APPROACH; GENETICS AND REPRODUCTION;

COLORECTAL NEOPLASMS; FAMILY; FEMALE; FOCUS GROUPS; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; HUMANS; MALE; MIDDLE AGED; PATIENT ACCEPTANCE OF HEALTH CARE;

EID: 0038279865     PISSN: 14222795     EISSN: None     Source Type: Journal    
DOI: 10.1159/000069543     Document Type: Article

References (24)

1. American Cancer Society Cancer Facts & Figures 2001. Atlanta, American Cancer Society, 2001.
2. Potter JD: Colorectal cancer: Molecules and populations. J Natl Cancer Inst 1999;91:916-932.
3. Lerman C, Narod S, Schulman K, Hughes C, Gomez-Caminero A, Bonney G, Gold K, Trock B, Main D, Lynch J, Fulmore C, Snyder C, Lemon SJ, Conway T, Tonin P, Lenoir G, Lynch H: BRCA1 testing in families with hereditary breast-ovarian cancer. A prospective study of patient decision making and outcomes. JAMA 1996;275:1885-1892.
4. Lerman C, Hughes C, Trock BJ, Myers RE, Main D, Bonney A, Abbaszadegan MR, Harty AE, Franklin BA, Lynch JF, Lynch HT: Genetic testing in families with hereditary nonpolyposis colon cancer. JAMA 1999;281:1618-1622.
5. Järvinen HJ, Mecklin JP, Sistonen P: Screening reduces colorectal cancer rate in families with hereditary nonpolyposis colorectal cancer. Gastroenterology 1995;108:1405-1411.
6. Järvinen HJ, Aarnio M, Mustonen H, Aktan-Collan K, Aaltonen LA, Peltomaki P, De La Chapelle A, Mecklin JP: Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer. Gastroenterology 2000;118:829-834.
7. Lynch HT, Watson P, Shaw TG, Lynch JF, Harty AE, Franklin BA, Kapler CR, Tinley ST, Liu B, Lerman C: Clinical impact of molecular genetic diagnosis, genetic counseling, and management of hereditary cancer. 2. Hereditary nonpolyposis colorectal carcinoma as a model. Cancer 1999;86:2457-2463.
8. Croyle RT, Lerman C: Interest in genetic testing for colon cancer susceptibility: Cognitive and emotional correlates. Prev Med 1993;22:284-292
9. Kinney AY, DeVellis BM, Skrzynia C, Millikan R: Genetic testing for colorectal carcinoma susceptibility. Cancer 2001;91:57-65.
10. Rodriguez-Bigas MA, Boland CR, Hamilton SR, Henson DE, Jass JR, Khan PM, Lynch H, Perucho M, Smyrk T, Sobin L, Srivastava S: A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: Meeting highlights and Bethesda guidelines. J Natl Cancer Inst 1997;89:1758-1762.
11. Nakahara M, Yokozaki H, Yasui W, Dohi K, Tahara E: Identification of concurrent germ-line mutations in hMSH2 and/or hMLH1 in Japanese hereditary nonpolyposis colorectal cancer kindreds. Cancer Epidemiol Biomark Prev 1997;6:1057-1064.
12. Vasen HF, Mecklin JP, Khan PM, Lynch HT: The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC). Dis Colon Rectum 1991;34:424-425.
13. Krueger RA: Focus Groups: A Practical Guide for Applied Research, ed 2. Thousand Oaks, Sage Publications, 1994, p 4.
14. Steward DW, Shamdasani PN: Focus Groups: Theory and Practice. Newbury Park, Sage Publications, 1990, p 15.
15. National Cancer Institute: Colon Cancer Family Registries Objectives. http://www.cfr.epi.uci.edu/colon/
16. Krippendorf, K: Content analysis: An introduction to its methodology. Beverly Hills, Sage Publications, 1980, p 21.
17. http://www.qsr.com.au/products/n4.html
18. Lerman C, Marshall J, Audrain J, Gomez-Caminero A: Genetic testing for colon cancer susceptibility: Anticipated reactions of patients and challenges to providers. Int J Cancer 1996;69:58-61.
19. Codori AM, Petersen GM, Miglioretti DL, Larkin EK, Bushey MT, Young C, Brensinger JD, Johnson K, Bacon JA, Booker SV: Attitudes toward colon cancer gene testing: Factors predicting test uptake. Cancer Epidemiol Biomark Prev 1999;8:345-351.
20. Vernon SW, Gritz ER, Peterson SK, Perz CA, Marani S, Amos CI, Baile WF: Intention to learn results of genetic testing for hereditary colon cancer. Cancer Epidemiol Biomark Prev 1999;8:353-360.
21. Petersen GM, Larkin E, Codori AM, Wang CY, Booker SV, Bacon J, Giardiello FM, Boyd PA: Attitudes toward colon cancer gene testing: Survey of relatives of colon cancer patients. Cancer Epidemiol Biomark Prev 1999;8:337-344.
22. Glanz K, Grove J, Lerman C, Gotay C, Le Marchand L: Correlates of intentions to obtain genetic counseling and colorectal cancer gene testing among at-risk relatives from three ethnic groups. Cancer Epidemiol Biomark Prev 1999;8:329-336.
23. Smith KR, Croyle RT: Attitudes toward genetic testing for colon cancer risk. Am J Public Health 1995;85:1435-1438.
24. Todora HM, Skinner CS, Gidday L, Ivanovich JL, Rawl S, Whelan AJ: Perceptions of genetic risk assessment and education among first-degree relatives of colorectal cancer patients and implications for physicians. Fam Pract 2001;18:367-372.