RBE of α-irradiation for in vitro relative transformation of rat tracheal epithelial cells

Annals of Occupational Hygiene

Volumn 46, Issue , 2002, Pages 285-287

  Kugel, C ^a   Tourdes, F ^a   Poncy, J L ^a   Fritsch, P ^a  

^a CEA DIF   (France)

Author keywords

actinide oxides; alpha irradiation; lung tumour; RBE; tracheal cell transformation

Indexed keywords

CELL DEATH; CYTOLOGY; GAMMA RAYS; IRRADIATION; LINEAR TRANSFORMATIONS; MATHEMATICAL TRANSFORMATIONS; RATS; TISSUE CULTURE;

ACTINIDE OXIDES; ALPHA IRRADIATION; CELL TRANSFORMATION; DOSE-EFFECT RELATIONSHIPS; RADIOACTIVE AEROSOLS; RBE; RELATIVE BIOLOGICAL EFFECTIVENESS; RELATIVE TRANSFORMATION;

CELLS;

EID: 0038273820     PISSN: 00034878     EISSN: 14753162     Source Type: Journal    
DOI: 10.1093/annhyg/46.suppl-1.285     Document Type: Conference Paper

References (12)

1. Dudoignon N, Guillet K, Rateau G, Fritsch P. (2002) Dose-effect relationship for malignant lung tumour induction after inhalation exposure of rats to 237NpO2 aerosols. Ann Occup Hyg; 46 (suppl. 1): 322-5.
2. Ford JR, Terzaghi-Howe M. (1993) Effects of 210Po alpha particles on survival and preneoplastic transformation of primary rat tracheal epithelial cells irradiated while in suspension or in the intact tissue. Radiat Res; 136: 89-96.
3. Hahn FF, Muggenburg BA, Guilmette RA, Boecker BB. (1999) Comparative stochastic effects of inhaled ?-and ?-particleemitting radionuclides in Beagle dogs. Radiat Res; 152: S19-22.
4. ICRP. (1979) Limits for intakes of radionuclides by workers. ICRP 30. Oxford: Pergamon Press.
5. Kitamura H, Fitzgerald DJ, Li LA, Barret JC, Nettesheim P. (1986) Morphological characterization of transformed colonies of rat tracheal epithelial cells culture exposed to carcinogen. Cancer Res; 46: 4631-41.
6. LeFoll L, Bailly I, Fritsch P. (1998) Calcul par simulation des parame`tres dosime´triques pour le noyau cellulaire apre`s irradiation alpha in vitro. J Chim Phys; 95: 808-11.
7. Lundgren DL, Hahn FF, Carlton WW, Griffith WC, Guilmette RA, Gillett NA. (1997) Dose responses from inhaled monodisperse aerosols of 244Cm2O3 in the lung, liver and skeleton of F344 rats and comparison with 239PuO2. Radiat Res; 147: 598-612.
8. Miller RC, Randers-Pherson G, Geard CR, Hall EJ, Brenner DJ. (1999) The oncogenic transforming potential of the passage of single particles through mammalian cell nuclei. Proc Natl Acad Sci USA; 96: 19-22.
9. Roberston JB, Koehler A, George J, Little JB. (1983) Oncogenic transformation of mouse Balb/3T3 cells by plutonium-238 ?-particles. Radiat Res; 96: 261-74.
10. Terzaghi-Howe M. (1989) Induction of preneoplastic alterations by X-rays and neutrons in exposed rat tracheas and isolated tracheal epithelial cells. Radiat Res; 120: 352-63.
11. Thomassen DG, Seiler FA, Shyr LJ, Griffith WC. (1990) Alpha-particles induce preneoplastic transformation of rat tracheal epithelial cells in culture. Int J Radiat Biol; 57: 395-405.
12. Yang TC, Gruenert DC, Holley WR, Curtis SB. (1990) Response of cultured human airway epithelial cells to X-rays and energetic ?-particles. Int J Radiat Biol; 58: 509-17.