Photosensitizing properties of palladium-tetraphenylporphycene on cultured tumour cells

Anti-Cancer Drug Design

Volumn 15, Issue 2, 2000, Pages 143-150

  Canete M ^a   Ortiz, A ^b   Juarranz, A ^a   Villanueva, A ^a   Nonell, S ^b   Borrell, J I ^b   Teixido J ^b   Stockert, J C ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b INSTITUT QUÍMIC DE SARRIÀ   (Spain)

Author keywords

HeLa cells; Mitotic spindle; Palladium tetraphenylporphycene; Photodynamic therapy; Photosensitization

Indexed keywords

DIPALMITOYLPHOSPHATIDYLCHOLINE; LIPOSOME; N,N DIMETHYLFORMAMIDE; PALLADIUM; TETRAPHENYLPORPHYRIN DERIVATIVE;

ARTICLE; CANCER CHEMOTHERAPY; CELL MEMBRANE; CELL NUCLEUS; CHROMATIN CONDENSATION; CHROMATOGRAPHY; CONTROLLED STUDY; CYTOPLASM; DRUG PURIFICATION; EVAPORATION; HELA CELL; HUMAN; HUMAN CELL; IRRADIATION; LD 50; METAPHASE; MICROTUBULE; MITOSIS INDEX; MITOSIS SPINDLE; PHOTODYNAMIC THERAPY; PHOTOSENSITIZATION; PRIORITY JOURNAL; TUMOR CELL CULTURE;

1,2-DIPALMITOYLPHOSPHATIDYLCHOLINE; CELL CYCLE; CELL SURVIVAL; DARKNESS; HELA CELLS; HUMANS; KINETICS; LIGHT; LIPOSOMES; METALLOPORPHYRINS; PHOTOSENSITIZING AGENTS; TUMOR CELLS, CULTURED;

EID: 0038267975     PISSN: 02669536     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Ali H., van Lier J.E. (1999) Metal complexes as photo- and radiosensitizers. Chemical Reviews, 99, 2379.
2. Aramendia P.F., Redmond R.W., Nonell S., Schuster W., Braslavsky S.E., Schaffner K., Vogel E. (1986) The photophysical properties of porphycenes: potential photodynamic therapy agents. Photochemistry and Photobiology, 44, 555.
3. Berg K., Moan J. (1988) Photodynamic effects of Photofrin II on cell division in human NHIK 3025 cells. International Journal of Radiation Biology, 53, 797.
4. Berg K., Moan J. (1992) Mitotic inhibition by phenylporphines and tetrasulfonated aluminium phthalocyanine in combination with light. Photochemistry and Photobiology, 56, 333.
5. Berg K., Moan J., Bommer J.C., Winkelman J.W. (1990) Cellular inhibition of microtubule assembly by photoactivated sulphonated meso-tetraphenylporphines. International Journal of Radiation Biology, 58, 475.
6. Cañete M., Lapeña M., Juarranz A., Vendrell V., Borrell J.I., Teixido J., Nonell S., Villanueva A. (1997) Uptake of tetraphenylporphycene and its photoeffects on actin and cytokeratin elements of HeLa cells. Anti-Cancer Drug Design, 12, 543.
7. Cañete M., Villanueva A., Dominguez V., Polo S., Juarranz A., Stockert J.C. (1998) Meso-tetraphenylporphyrin: photosensitizing properties and cytotoxic effects on cultured tumor cells. International Journal of Oncology, 13, 497.
8. Dougherty T.J., Marcus S.L. (1992) Photodynamic therapy. European Journal of Cancer, 28, 1734.
9. Franck B., Nonn A. (1995) Neuatige Porphyrinoide für Chemie und Medizin durch biomimetische Synthesen. Angewandte Chemie, 107, 1941.
10. Ginevra F., Biffanti S., Pagnan A., Biolo R., Reddi E., Jori G. (1990) Delivery of the tumour photosensitizer zinc(II)-phthalocyanine to serum proteins by different liposomes: studies in vitro and in vivo. Cancer Letters, 49, 59.
11. Guardiano M., Biolo R., Jori G., Schaffner K. (1989) Tetra-n-propylporphycene as a tumour localizer: pharmacokinetic and phototherapeutic studies in mice. Cancer Letters, 44, 1.
12. Hemmilä I.A. (1989) Fluorescent labels for use in fluorescence immunoassays. Applied Fluorescence Technology, 1, 1.
13. Jacobson B.S. (1983) Interaction of the plasma membrane with the cytoskeleton: an overview. Tissue and Cell Research, 15, 829.
14. Jordan M.A., Wendell K., Gardiner S., Derry W.B., Copp H., Wilson L. (1996) Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death. Cancer Research, 56, 816.
15. Jori G. (1992) Far-red absorbing photosensitizers: their use in the photodynamic therapy of tumours. Journal of Photochemistry and Photobiology, A: Chemistry, 62, 371.
16. Jori G. (1996) Tumour photosensitizers: approaches to enhance the selectivity and efficiency of photodynamic therapy. Journal of Photochemistry and Photobiology, B: Biology, 36, 87.
17. Juarranz A., Villanueva A., Diaz V., Cañete M. (1995) Photodynamic effects of the cationic porphyrin, mesotetra-(4N-methylpyridyl)porphine, on microtubules of HeLa cells. Journal of Photochemistry and Photobiology, B: Biology, 27, 47.
18. Juarranz A., Villanueva A., Cañete M., Stockert J.C. (1996) Fluorescent porphyrin counterstaining of chromatin DNA in conjunction with immunofluorescence methods using FITC-labelled antibodies. Journal of Microscopy, 182, 46.
19. Lee C., Wu S.S., Chen L.B. (1995) Photosensitization by 3,3′-dihexyloxacarbocyanine iodide: specific disruption of microtubules and inactivation of organelle motility. Cancer Research, 55, 2063.
20. Martin S.J., Cotter T.G. (1990) Disruption of microtubules induces an endogenous suicide pathway in human leukaemia HL-60 cells. Cell and Tissue Kinetics, 23, 545.
21. Merlin J., Azzi S., Lignon D., Ramacci C., Zeghari N., Guillemin F. (1992) MTT assays allow quick and reliable measurement of the response of human tumour cells to photodynamic therapy. European Journal of Cancer, 28, 1452.
22. Milanesi C., Biolo R., Jori G., Schaffner K. (1991) Experimental photodynamic therapy with tetrapropyl-porphycene: ultrastructural studies on the mechanism of tumour photodamage. Lasers in Medical Science, 6, 437.
23. Moan J., Berg K. (1992) Photochemotherapy of cancer: experimental research. Photochemistry and Photobiology, 55, 931.
24. Nonell S., Aramendia P.F., Heihoff K., Negri R.M., Braslavsky S.E. (1990) Laser-induced optoacoustics combined with near-infrared emission. An alternative approach for the determination of intersystem crossing quantum yield applied to porphycenes. Journal of Physical Chemistry, 94, 5879.
25. Nonell S., Bou N., Borrell J.I., Teixido J., Villanueva A., Juarranz A., Cañete M. (1995) Synthesis of 2,7,12,17-tetraphenylporphycene (TPPo). First aryl-substituted porphycene for the photodynamic therapy of tumors. Tetrahedron Letters, 36, 3405.
26. Rihter B.D., Kenney M.E., Ford W.E., Rodgers M.A.J. (1993) Photochromic reactions involving palladium(II) octabutoxynaphthalocyanine and molecular oxygen. Journal of the American Chemical Society, 115, 8146.
27. Rosenthal I. (1991) Phthalocyanines as photodynamic sensitizers. Photochemistry and Photobiology, 53, 859.
28. Rumsey W.L., Vanderkooi J.M., Wilson D.F. (1988) Imaging of phosphorescence: a novel method for measuring oxygen distribution in perfused tissue. Science, 241, 1649.
29. Schuitmaker J.J., Baas P., van Leengoed H.L.L.M., van der Meulen F.W., Star W.M., van Zandwijk N. (1996) Photodynamic therapy: a promising new modality for the treatment of cancer. Journal of Photochemistry and Photobiology, B: Biology, 34, 3.
30. Spikes J.D. (1986) Phthalocyanines as photosensitizers in biological systems and for the photodynamic therapy of tumors. Photochemistry and Photobiology, 43, 691.
31. Sporn L.A., Foster T.H. (1992) Photofrin and light induces microtubule depolymerization in cultured human endothelial cells. Cancer Research, 52, 3443.
32. Stockert J.C., Juarranz A., Villanueva A., Cañete M. (1996) Photodynamic damage to HeLa cell microtubules induced by thiazine dyes. Cancer Chemotherapy and Pharmacology, 39, 167.
33. Sutedja T.G., Postmus P.E. (1996) Photodynamic therapy in lung cancer. A review. Journal of Photochemistry and Photobiology, B: Biology, 36, 199.
34. Valduga G., Reddi E., Garbisa S., Jori G. (1998) Photosensitization of cells with different metastatic potential by liposome-delivered Zn(II)-phthalocyanine. International Journal of Cancer, 75, 412.
35. Vallés M.A., Biolo R., Bonnett R., Cañete M., Gómez A.M., Jori G., Juarranz A., McManus K.A., Okolo K.T., Soncin M., Villanueva A. (1995) Benzoporphyrins as photosensitizers for the photodynamic therapy of cancer. In Photodynamic Therapy of Cancer. Jori G., Moan J., Ehrenberg B. (eds), vol. 3, pp. 11-21.
36. Vanderkooi J.M., Maniara G., Green T.J., Wilson D.F. (1987) An optical method for measurement of dioxygen concentration based upon quenching of phosphorescence. Journal of Biological Chemistry, 262, 5476.
37. Verhaegen S. (1998) Microscopical study of cell death via apoptosis. European Microscopy and Analysis, 51, 31.
38. Verlhac J.B., Gaudemer A., Kraljic I. (1984) Water-soluble porphyrins and metalloporphyrins as photosensitizers in aerated aqueous solutions. I. Detection and determination of quantum yield of formation of singlet oxygen. Nouveau Journal de Chimie, 8, 401.
39. Vidai B.C., Barbisan L.F., Maria S.S., Russo J., Mello M.L.S. (1996) Apoptosis: identification by a critical electrolyte concentration method. Apoptosis, 1, 218.
40. Villanueva A., Juarranz A., Diaz V., Gomez J., Cañete M. (1992) Photodynamic effects of a cationic mesosubstituted porphyrin in cell cultures. Anti-Cancer Drug Design, 7, 297.
41. Villanueva A., Cañete M., Nonell S., Borrell J.I., Teixido J., Juarranz A. (1996) Photodamaging effects of tetraphenylporphycene in a human carcinoma cell line. Anti-Cancer Drug Design, 11, 89.
42. Vogel E., Köcher M., Schmickler H., Lex J. (1986) Porphycene. A novel porphin isomer. Angewandte Chemie. International Edition in English, 25, 257.