Roles of the conserved CCAAT and GC boxes of the human and mouse type II transforming growth factor-β receptor genes

Molecular Reproduction and Development

Volumn 65, Issue 4, 2003, Pages 353-365

  Bernadt, Cory T ^a,b   Rizzino, Angie ^a,b  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Differentiation; EC cells; Ets binding sites; F9 differentiated cells; NF Y; Sp1; Transcription

Indexed keywords

CIS ACTING ELEMENT; NUCLEAR FACTOR Y; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SP1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARCINOMA CELL; CCAAT BOX; CELL DIFFERENTIATION; CONTROLLED STUDY; DNA FLANKING REGION; EMBRYONAL CARCINOMA; GC RICH SEQUENCE; GENE CONTROL; GENE EXPRESSION REGULATION; GENE FUNCTION; HUMAN; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN FUNCTION; PROTEIN MOTIF; REGULATORY MECHANISM; REGULATORY SEQUENCE; TRANSCRIPTION INITIATION SITE;

ANIMALS; CARCINOMA, EMBRYONAL; CCAAT-BINDING FACTOR; CELL DIFFERENTIATION; CELL LINE, TUMOR; CONSERVED SEQUENCE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MICE; PROMOTER REGIONS (GENETICS); RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; REGULATORY SEQUENCES, NUCLEIC ACID; RNA, MESSENGER; SP1 TRANSCRIPTION FACTOR; TRANSFECTION;

MAMMALIA;

EID: 0038262004     PISSN: 1040452X     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrd.10313     Document Type: Article

References (44)

1. Ahmad I. 1995. Mash-1 is expressed during ROD photoreceptor differentiation and binds an E-box, E(opsin)-1 in the rat opsin gene. Brain Res Dev Brain Res 90:184-189.
2. Ammanamanchi S, Kim SJ, Sun LZ, Brattain MG. 1998. Induction of transforming growth factor-beta receptor type II expression in estrogen receptor-positive breast cancer cells through SP1 activation by 5-aza-2′-deoxycytidine. J Biol Chem 273:16527-16534.
3. Bae HW, Geiser AG, Kim DH, Chung MT, Burmester JK, Sporn MB, Roberts AB, Kim SJ. 1995. Characterization of the promoter region of the human transforming growth factor-beta type II receptor gene. J Biol Chem 270:29460-29468.
4. Bi W, Wu L, Coustry F, de Crombrugghe B, Maity SN. 1997. DNA binding specificity of the CCAAT-binding factor CBF/NF-Y. J Biol Chem 272:26562-26572.
5. Birchenall-Roberts MC, Falk LA, Kasper J, Keller J, Faltynek CR, Ruscetti FW. 1991. Differential expression of transforming growth factor-beta 1 (TGF-beta 1) receptors in murine myeloid cell lines transformed with oncogenes. Correlation with differential growth inhibition by TGF-beta 1. J Biol Chem 266:9617-9621.
6. Boucher PD, Ruch PJ, Hines RN. 1993. Specific nuclear protein binding to a negative regulatory element on the human CYP1A1 gene. J Biol Chem 268:17384-17391.
7. Bucher P. 1990. Weight matrix descriptions of four eukaryotic RNA polymerase II promoter elements derived from 502 unrelated promoter sequences. J Mol Biol 212:563-578.
8. Carrozza MJ, John S, Sil AK, Hopper JE, Workman JL. 2002. Gal80 confers specificity on HAT complex interactions with activators. J Biol Chem 277:24648-24652.
9. Chang J, Lee C, Hahm KB, Yi Y, Choi SG, Kim SJ. 2000. Overexpression of ERT(ESX/ESE-1/ELF3), an ets-related transcription factor, induces endogenous TGF-beta type II receptor expression and restores the TGF-beta signaling pathway in Hs578t human breast cancer cells. Oncogene 19:151-154.
10. Choi SG, Yi Y, Kim YS, Kato M, Chang J, Chung HW, Hahm KB, Yang HK, Rhee HH, Bang YJ, Kim SJ. 1998. A novel ets-related transcription factor, ERT/ESX/ESE-1, regulates expression of the transforming growth factor-beta type II receptor. J Biol Chem 273: 110-117.
11. Dignam JD, Lebovitz RM, Roeder RG. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11:1475-1489.
12. Jennings R, Alsarraj M, Wright KL, Mufioz-Antonia T. 2001. Regulation of the human transforming growth factor beta type II receptor gene promoter by novel Sp1 sites. Oncogene 20:6899-6909.
13. Jepsen K, Rosenfeld MG. 2002. Biological roles and mechanistic actions of co-repressor complexes. J Cell Sci 115:689-698.
14. Kadonaga JT, Jones KA, Tjian R. 1986. Promoter-specific activation of RNA polymerase II transcription by Sp1. Trends Biochem Sci 11: 20-23.
15. Kelly DL, Rizzino A. 1999. Growth regulatory factors and carcinogenesis: The roles played by transforming growth factor beta, its receptors and signaling pathways. Anticancer Res 19:4791-4807.
16. Kelly D, Scholtz B, Orten DJ, Hinrichs SH, Rizzino A. 1995. Regulation of the transforming growth factor-beta 2 gene promoter in embryonal carcinoma cells and their differentiated cells: Differential utilization of transcription factors. Mol Reprod Dev 40:135-145.
17. Kelly D, Kim SJ, Rizzino A. 1998. Transcriptional activation of the type II transforming growth factor-beta receptor gene upon differentiation of embryonal carcinoma cells. J Biol Chem 273:21115-21124.
18. Kim DH, Chang JH, Lee KH, Lee HY, Kim SJ. 1997. Mechanism of E1A-induced transforming growth factor-beta (TGF-beta) resistance in mouse keratinocytes involves repression of TGF-beta type II receptor transcription. J Biol Chem 272:688-694.
19. Kim JH, Wilder PJ, Hou J, Nowling T, Rizzino A. 2002. Activation of the murine type II transforming growth factor-beta receptor gene: Up-regulation and function of the transcription factor Elf-3/Ert/Esx/ Ese-1. J Biol Chem 277:17520-17530.
20. Kingsley-Kallesen ML, Kelly D, Rizzino A. 1999. Transcriptional regulation of the transforming growth factor-beta2 promoter by cAMP-responsive element-binding protein (CREB) and activating transcription factor-1 (ATF-1) is modulated by protein kinases and the coactivators p300 and CREB-binding protein. J Biol Chem 274:34020-34028.
21. Lee BI, Park SH, Kim JW, Sausville EA, Kim HT, Nakanishi O, Trepel JB, Kim SJ. 2001. MS-275, a histone deacetylase inhibitor, selectively induces transforming growth factor beta type II receptor expression in human breast cancer cells. Cancer Res 61:931-934.
22. Lin H, Yutzey KE, Konieczny SF. 1991. Muscle-specific expression of the troponin I gene requires interactions between helix-loop-helix muscle regulatory factors and ubiquitous transcription fac. Mol Cell Biol 11:267-280.
23. Liu Y, Zhong X, Li W, Brattain MG, Banerji SS. 2000. The role of Sp1 in the differential expression of transforming growth factor-beta receptor type II in human breast adenocarcinoma MCF-7 cells. J Biol Chem 275:12231-12236.
24. Ma YG, Rosfjord E, Huebert C, Wilder P, Tiesman J, Kelly D, Rizzino A. 1992. Transcriptional regulation of the murine k-FGF gene in embryonic cell lines. Dev Biol 154:45-54.
25. Mantovani R, Li XY, Pessara U, Hooft VH, Benoist C, Mathis D. 1994. Dominant negative analogs of NF-YA. J Biol Chem 269:20340-20346.
26. Martin GR. 1980. Teratocarcinomas and mammalian embryogenesis. Science 209:768-776.
27. Muñoz-Antonia T, Li X, Reiss M, Jackson R, Antonia S. 1996. A mutation in the transforming growth factor beta type II receptor gene promoter associated with loss of gene expression. Cancer Res 56: 4831-4835.
28. Okamoto A, Jiang W, Kim SJ, Spillare EA, Stoner GD, Weinstein IB, Harris CC. 1994. Overexpression of human cyclin D1 reduces the transforming growth factor beta (TGF-beta) type II receptor and growth inhibition by TGF-beta 1 in an immortalized human esophageal epithelial cell line. Proc Natl Acad Sci USA 91:11576-11580.
29. Park SH, Lee SR, Kim BC, Cho EA, Patel SP, Kang HB, Sausville EA, Nakanishi O, Trepel JB, Lee BI, Kim SJ. 2002. Transcriptional regulation of the transforming growth factor beta type II receptor gene by histone acetyltransferase and deacetylase is mediated by NF-Y in human breast cancer cells. J Biol Chem 277:5168-5174.
30. Rizzino A. 1987. Appearance of high affinity receptors for type beta transforming growth factor during differentiation of murine embryonal carcinoma cells. Cancer Res 47:4386-4390.
31. Rizzino A. 1988. Transforming growth factor-beta: Multiple effects on cell differentiation and extracellular matrices. Dev Biol 130:411-422.
32. Rizzino A. 1998. Transcriptional regulation in an in vitro model system for mammalian embryogenesis. In: Dickson RB, Salomon DS, editors. Hormones and growth factors in development and neoplasia. New York: Wiley-Liss, Inc. p 115-129.
33. Rizzino A. 2002. Embryonic stem cells provide a powerful and versatile model system. Vitam Horm 64:1-42.
34. Rizzino A, Crowley C. 1980. Growth and differentiation of embryonal carcinoma cell line F9 in defined media. Proc Natl Acad Sci USA 77: 457-461.
35. Rizzino A, Orme LS, De Larco JE. 1983. Embryonal carcinoma cell growth and differentiation. Production of and response to molecules with transforming growth factor activity. Exp Cell Res 143:143-152.
36. Roberts AB, Sporn MB. 1993. Physiological actions and clinical applications of transforming growth factor-beta (TGF-beta). Growth Factors 8:1-9.
37. Roder K, Wolf SS, Beck KF, Schweizer M. 1997. Cooperative binding of NF-Y and Sp1 at the DNase I-hypersensitive site, fatty acid synthase insulin-responsive element 1, located at -500 in the rat fatty acid synthase promoter. J Biol Chem 272:21616-21624.
38. Scholtz B, Lamb K, Rosfjord E, Kingsley M, Rizzino A. 1996. Appearance of nuclear protease activity after embryonal carcinoma cells undergo differentiation. Dev Biol 173:420-427.
39. Shibata H, Spencer TE, Onate SA, Jenster G, Tsai SY, Tsai MJ, O'Malley BW. 1997. Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action. Recent Prog Horm Res 52:141-164.
40. Sinha S, Maity SN, Lu J, de Crombrugghe B. 1995. Recombinant rat CBF-C, the third subunit of CBF/NFY, allows formation of a protein-DNA complex with CBF-A and CBF-B and with yeast HAP2 and HAP3. Proc Natl Acad Sci USA 92:1624-1628.
41. Song SU, Oh IS, Lee B, Suh JK, Kim JH, Cha YD, Lee KH, Kim DH. 2001. Identification of a negative Cis-regulatory element and multiple DNA binding proteins that inhibit transcription of the transforming growth factor-beta type II receptor gene. Gene 262:179-187.
42. Wilder PJ, Bernadt CT, Kim JH, Rizzino A. 2002. Stimulation of the murine type II transforming growth factor-beta receptor promoter by the transcription factor Egr-1. Mol Reprod Dev 63:282-290.
43. Wright KL, Moore TL, Vilen BJ, Brown AM, Ting JP. 1995. Major histocompatibility complex class II-associated invariant chain gene expression is up-regulated by cooperative interactions of Sp1 and NF-Y. J Biol Chem 270:20978-20986.
44. Xu Y, Banville D, Zhao H, Zhao X, Shen S., 2001., Transcriptional activity of the SHP-1 gene in MCF7 cells is differentially regulated by binding of NF-Y factor to two distinct CCAAT-elements. Gene 269:141-153.