Hemodynamic and proinflammatory actions of endothelin-1 in guinea pig small intestine submucosal microcirculation

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 284, Issue 6 47-6, 2003, Pages

  King VanVlack, C E ^a   Mewburn, J D ^a   Chapler, C K ^a   MacDonald, P H ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

Blood flow

Indexed keywords

DIPHENHYDRAMINE; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; HISTAMINE H1 RECEPTOR; THROMBOCYTE ACTIVATING FACTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ERYTHROCYTE; GUINEA PIG; HEMODYNAMICS; INTESTINE BLOOD FLOW; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BLOCKING;

EID: 0038247701     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.00373.2001     Document Type: Article

References (30)

1. Allcock GH, Warner TD, and Vane JR. Roles of endothelin receptors in the regional and systemic vascular responses to ET-1 in the anaesthetized ganglion-blocked rat: use of selective antagonists. Br J Pharmacol 116: 2482-2486, 1995.
2. Baveja R, Zhang JX, and Clemens MG. In vivo assessment of endothelin-induced heterogeneity of hepatic tissue perfusion. Shock 15: 186-192, 2001.
3. Battistini B and Dussault P. Blocking of the endothelin system; the development of receptor anatagonists. Pulm Pharmacol 11: 97-112, 1998.
4. Boros M, Massberg S, Baranyi L, Okada H, and Messmer K. Endothelin-1 induces leukocyte adhesion in submucosal venules of the rat small intestine. Gastroenterology 114: 103-114, 1998.
5. Cargill RI, Kelly DG, Clark RA, and Lipworth GJ. Hypoxemia and release of endothelin-1. Thorax 50: 1308-1310, 1995.
6. Casals-Stenzel J, Muacevic G, and Weber KH. Pharmacological actions of WEB-2086, a new specific antagonist of platelet activating factor. J Pharmacol Exp Ther 241: 974-981, 1987.
7. Cifkova R, Pit'ha J, Trunecka P, Lanska V, Jindra A, Plaskova M, Peterkova L, Hrncarkova H, and Horky K. Blood pressure, endothelial function, and circulating endothelin concentratiosn in liver transplant receipients. J Hypertens 19: 1359-1367, 2001.
8. D'Orleans-Juste P, Claing A, Warner TD, Yano M, and Télémaque S. Characterization of receptors for endothelins in the perfused arterial and venous mesenteric vasculatures of the rat. Br J Pharmacol 110: 687-692, 1993.
9. Elferink JGR and DeKoster BM. The involvement of protein kinase G in stimulation of neutrophil migration by endothelins. Eur J Pharmacol 350: 285-291, 1998.
10. Filep JG, Clozel M, Fournier A, and Foldes-Filep E. Characterization of receptors mediating vascular responses to endothelin-1 in the conscious rat. Br J Pharmacol 113: 845-852, 1994.
11. Filep JG, Sirois MG, Rousseau A, Fournier A, and Sirois P. Effects of endothelin-1 on vascular permeability in the conscious rat: interactions with platelet-activating factor. Br J Pharmacol 104: 797-804, 1991.
12. Ishikawa K, Ihara M, Noguchi K, Mase T, Mino N, Saeki T, Fukuroda T, Fukami T, Ozaki S, Nagase T, Nishikibe M, and Yano M. Biochemical and pharmacological profile of a potent and selective endothelin B-receptor antagonist, BQ-788. Proc Natl Acad Sci USA 91: 4892-4896, 1994.
13. Johnson RJ, Fink GD, and Galligan JJ. Mechanisms of endothelin-induced venoconstriction in isolated guinea pig mesentery. J Pharmacol Exp Ther 289: 762-767, 1999.
14. King-VanVlack CE, Mewburn JD, and Chapler CK. Receptor-mediated actions of endothelin-1 in canine small intestine. Am J Physiol Gastrointest Liver Physiol 277: G1131-G1136, 1999.
15. King-Van Vlack CE, Curtis SE, Mewburn JD, Chapler CK, and Cain SM. Endothelial and neural interactions in the regulation of vascular tone in canine skeletal muscle. Adv Exp Med Biol 411: 287-293, 1997.
16. Kubes P and Gaboury JP. Rapid mast cell activation causes leukocyte-dependent and independent permeability alterations. Am J Physiol Heart Circ Physiol 271: H2438-H2446, 1996.
17. Laux V and Seiffge S. Mediator-induced changes in macromolecular permeability in the rat mesenteric microcirculation. Microvasc Res 49: 117-133, 1995.
18. B receptors. J Cardiovasc Pharmacol 39: 533-543, 2002.
19. Lopez-Belmonte J and Whittle BJR. Endothelin-1 induces neutrophil-independent vascular injury in the rat gastric microcirculation. Eur J Pharmacol 278: R7-R9, 1995.
20. Lopez-Farre A, Caramelo C, Esteban A, Alberola ML, Millas I, Monton M, and Casado S. Effects of aspirin on plateletneutrophil interactions: role of nitric oxide and endothelin-1. Circ Res 91: 2080-2088, 1995.
21. Masaki T. Possible role of endothelin in endothelial regulation of vascular tone. Annu Rev Pharmacol Toxicol 35: 235-255, 1995.
22. A receptors. Shock 9: 177-183, 1998.
23. Menger MD, Rucker M, and Vollmar B. Capillary dysfunction in striated muscle ishchemia/reperfusion: on the mechanisms of capillary "no-reflow." Shock 8: 2-7, 1997.
24. B receptors in rat isolated small mesenteric arteries. Br J Pharmacol 120: 1376-1382, 1997.
25. Oktar BK, Coskun T, Bozkurt A, Yegen BC, Yuksel M, Haklar G, Bilsel S, Aksungar FB, Cetinel S, Granger DN, and Kurtel H. Endothelin-1-induced PMN infiltration and mucosal dysfunction in the rat small intestine. Am J Physiol Gastrointest Liver Physiol 279: G483-G491, 2000.
26. 2 inhbitiors, PAF acetylhydrolases, PAF receptor antagonists and free radical scavengers. Prostaglandins, Leukotrienes and Essential Fatty Acids 61: 65-82, 1999.
27. A receptors. Am J Physiol Heart Circ Physiol 281: H2680-H2686, 2001.
28. Toothaker LE. Multiple Comparisons for Researchers. Newbury Park, CA: Sage, 1991.
29. Wagner JE and Manning PJ. The Biology of the Guinea Pig. New York: Academic, 1976.
30. Wilson MA, Steeb GD, and Garrison RN. Endothelins mediate intestinal hypoperfusion during bacteremia. J Surg Res 55: 168-175, 1993.