Characterization of the toxicity, mutagenicity, and carcinogenicity of methacrylonitrile in F344 rats and B6C3F1 mice

Archives of Toxicology

Volumn 77, Issue 4, 2003, Pages 233-242

  Nyska, Abraham ^a   Ghanayem, Burhan I ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Atrophy; B6C3F1 mouse; Carcinogenicity; F344 N rat; Methacrylonitrile; Olfactory epithelium

Indexed keywords

ACRYLONITRILE; AMIDE; AMINE; BIOLOGICAL MARKER; COPOLYMER; CYSTEINE DERIVATIVE; ELASTOMER; ESTER DERIVATIVE; METHACRYLONITRILE; N ACETYL S (2 CYANOPROPYL)CYSTEINE; N ACETYL S (2 HYDROXYPROPYL)CYSTEINE; NITRILE; PLASTIC; POLYMER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATROPHY; CARCINOGENICITY; CELL VACUOLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; EXPOSURE; FEMALE; GENOTOXICITY; INCIDENCE; LIVER INJURY; MALE; METAPLASIA; MOUSE; MUTAGENICITY; NONHUMAN; NOSE INJURY; OLFACTORY EPITHELIUM; PRIORITY JOURNAL; RAT; SURVIVAL; TOXICITY TESTING; URINARY EXCRETION;

ANIMALIA;

EID: 0038243861     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-002-0434-7     Document Type: Article

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