Methylprednisolone inhibits low-flow hypoxia-induced mitochondrial dysfunction in isolated perfused rat liver

Critical Care Medicine

Volumn 31, Issue 5, 2003, Pages 1468-1474

  Motoyama, Satoru ^a   Saito, Satoshi ^a   Minamiya, Yoshihiro ^a   Saito, Reijiro ^a   Nakamura, Masakatsu ^a   Okuyama, Manabu ^a   Imano, Hiroshi ^a   Ogawa, Jun Ichi ^a  

^a AKITA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Hydrogen peroxide; Hypoxia; Liver; Methylprednisolone; Mitochondria

Indexed keywords

ASPARTATE AMINOTRANSFERASE; FLUORESCENT DYE; HYDROGEN PEROXIDE; METHYLPREDNISOLONE SODIUM SUCCINATE; MITOCHONDRIAL ENZYME; RHODAMINE 123; SCAVENGER;

ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CHEMOLUMINESCENCE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME RELEASE; FLUORESCENCE ANALYSIS; ISOLATED LIVER; LIVER BLOOD FLOW; LIVER ISCHEMIA; LIVER MITOCHONDRION; LIVER PROTECTION; MALE; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANOXIA; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL; CHEMILUMINESCENT MEASUREMENTS; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; FREE RADICAL SCAVENGERS; HYDROGEN PEROXIDE; IN SITU NICK-END LABELING; LIVER; MALE; MEMBRANE POTENTIALS; METHYLPREDNISOLONE; MITOCHONDRIA, LIVER; MITOCHONDRIAL DISEASES; PROSPECTIVE STUDIES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0038242504     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000066176.49774.CC     Document Type: Article

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