Pharmacokinetic-based total intravenous anaesthesia using remifentanil and propofol for surgical myocardial revascularization

European Journal of Anaesthesiology

Volumn 20, Issue 5, 2003, Pages 385-390

  Guarracino, Fabio ^a,b   Penzo, D ^a   De Cosmo, D ^a   Vardanega, A ^a   De Stefani, R ^a  

^a Ospedale Umberto I   (Italy)

^b Cardiac Anaesthesia and ICU   (Italy)

Author keywords

Anaesthesia, intravenous; Anaesthetics, intravenous, propofol; Cardiac surgical procedures, myocardial revascularization, coronary artery bypass

Indexed keywords

ANALGESIC AGENT; ANESTHETIC AGENT; ATROPINE; CISATRACURIUM; FLUNITRAZEPAM; INTRAVENOUS ANESTHETIC AGENT; METARAMINOL; PIPERIDINE DERIVATIVE; PROPOFOL; REMIFENTANIL; TRAMADOL;

ADULT; AGED; ANESTHESIA INDUCTION; ARTICLE; ARTIFICIAL VENTILATION; BRADYCARDIA; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG EFFECT; ELECTROCARDIOGRAPHY; ENDOTRACHEAL INTUBATION; EXTUBATION; FEMALE; HEART HEMODYNAMICS; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MUSCLE ISCHEMIA; HEART MUSCLE REVASCULARIZATION; HEART OUTPUT; HEART RATE; HEART RATE VARIABILITY; HEART SURGERY; HEMODYNAMIC MONITORING; HEMODYNAMICS; HUMAN; HYPOTENSION; INTRAOPERATIVE PERIOD; INTRAVENOUS ANESTHESIA; MALE; MEAN ARTERIAL PRESSURE; PEROPERATIVE CARE; POSTOPERATIVE CARE; POSTOPERATIVE PAIN; PREMEDICATION; ST SEGMENT; TRANSESOPHAGEAL ECHOCARDIOGRAPHY;

ADULT; AGED; ANESTHETICS, COMBINED; ANESTHETICS, INTRAVENOUS; CARDIAC OUTPUT; CORONARY ARTERY BYPASS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROCARDIOGRAPHY; FEMALE; HEART RATE; HEMODYNAMIC PROCESSES; HUMANS; INTRAOPERATIVE CARE; MALE; MIDDLE AGED; PIPERIDINES; PROPOFOL;

EID: 0038240786     PISSN: 02650215     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0265021503000589     Document Type: Article

References (20)

1. Lunn JK, Stanley TH, Eisele J, Webster L, Woodward A. High-dose fentanyl anesthesia for coronary artery surgery. Anesth Analg 1979; 58: 390-395.
2. Sebel PS, Bovill JG, Boekhorst RAA, Rog N. Cardiovascular effects of high-dose fentanyl anaesthesia. Acta Anaesthesiol Scand 1982; 26: 308-315.
3. Wynands JE, Townsend GE, Wong P, Whalley DG, Srikant CB, Patel YC. Blood pressure response and plasma fentanyl concentrations during high- and very high-dose fentanyl anesthesia for coronary artery surgery. Anesth Analg 1983; 62: 661-665.
4. Hilgenberg JC. Intraoperative awareness during highdose fentanyl-oxygen anesthesia. Anesthesiology 1981; 54: 341-343.
5. Caspi J, Klausner JM, Safadi T, Amar R, Rozin RR, Merin G. Delayed respiratory depression following fentanyl anesthesia for cardiac surgery. Crit Care Med 1988; 16: 238-240.
6. De Lange S, Stanley TH, Boscoe MJ. Alfentanil-oxygen anaesthesia for coronary artery surgery. Br J Anaesth 1981; 53: 1291-1296.
7. Phillips AS, McMurray TJ, Mirakhur RK, Gibson FM, Elliott P. Propofol-fentanyl anaesthesia in cardiac surgery: a comparison in patients with good and impaired left ventricular function. Anaesthesia 1993; 48: 661-663.
8. Bell J, Sartain J, Wilkinson GA, Sherry KM. Propofol and fentanyl anaesthesia for patients with low cardiac output state undergoing cardiac surgery: comparison with highdose fentanyl anaesthesia. Br J Anaesth 1994; 73: 162-166.
9. Roekaerts PM, Gerrits HJ, Timmerman BE, de Lange S. Continuous infusions of alfentanil and propofol for coronary artery surgery. J Cardiothorac Vasc Anesth 1995; 9: 362-367.
10. D'Attelis N, Nicolas-Robin A, Delayance S, Carpentier A, Baron JF. Early extubation after mitral valve surgery: a target-controlled infusion of propofol and low-dose sufentanil. J Cardiothorac Vasc Anesth 1997; 11: 467-473.
11. Olivier P, Sirieix D, Dassier P, D'Attellis N, Baron JF. Continuous infusion of remifentanil and target-controlled infusion of propofol for patients undergoing cardiac surgery: a new approach for scheduled early extubation. J Cardiothorac Vasc Anesth 2000; 14: 29-35.
12. Vuyk J. Pharmacokinetic and pharmacodynamic interactions between opioids and propofol. J Clin Anesth 1997; 9: 23S-26S.
13. Rosow CE. An overview of remifentanil. Anesth Analg 1999; 89: S1-S3.
14. Shafer SL, Gregg KM. Algorithm to rapidly achieve and maintain stable drug concentrations at the site of drug effect with a computer-controlled infusion pump. J Pharmacokinet Biopharm 1992; 20: 147-169.
15. Minto CF, Schnider TW, Egan TD, et al. Influence of age and gender on the pharmacokinetics and pharmacodynamics of remifentanil. I. Model development. Anesthesiology 1997; 86: 10-23.
16. Minto CF, Schnider TW, Shafer SL. Pharmacokinetics and pharmacodynamics of remifentanil. II. Model application. Anesthesiology 1997; 86: 24-33.
17. Marsh B, White M, Morton N, Kenny GN. Pharmacokinetic model driven infusion of propofol in children. Br J Anaesth 1991; 67: 41-48.
18. Glen JB. The development of 'Diprifusor': a TCI system for propofol. Anaesthesia 1998; 53 (Suppl 1): 13-21.
19. Gepts E. Pharmacokinetic concepts for TCI anaesthesia. Anaesthesia 1998; 53 (Suppl 1): 4-12.
20. Bigatello LM, Coppo A. Intraoperative monitoring of myocardial ischemia. Minerva Anestesiol 2001; 67: 314-319.