Promotion of corneal epithelial wound healing in diabetic rats by the combination of a substance P-derived peptide (FGLM-NH2) and insulin-like growth factor-1

Diabetologia

Volumn 46, Issue 6, 2003, Pages 839-842

  Nakamura, M ^a,b   Kawahara, M ^a   Morishige, N ^b   Chikama, T ^b   Nakata, K ^a   Nishida, T ^b  

^a SANTEN PHARMACEUTICAL CO LTD   (Japan)

^b YAMAGUCHI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Corneal epithelium; Diabetes; Insulin like growth factor 1; Substance P derived peptide; Wound healing

Indexed keywords

EYE DROPS; PEPTIDE DERIVATIVE; PHENYLALANYLGLYCYLLEUCYLMETHIONINAMIDE; SOMATOMEDIN C; STREPTOZOCIN; SUBSTANCE P DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORNEA EPITHELIUM; CORNEA INJURY; DIABETES MELLITUS; DRUG EFFECT; KERATOPATHY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; WOUND CLOSURE; WOUND HEALING;

ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; EPITHELIUM, CORNEAL; INSULIN-LIKE GROWTH FACTOR I; MALE; OLIGOPEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE VALUES; WOUND HEALING;

EID: 0038235847     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-003-1105-9     Document Type: Article

References (10)

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10. Chikama T, Fukuda K, Morishige N, Nishida T (1998) Treatment of neurotrophic keratopathy with substance-P-derived peptide (FGLM) and insulin-like growth factor I. Lancet 351:1783-1784