Good preclinical bioanalytical chemistry requires proper sampling from laboratory animals: Automation of blood and microdialysis sampling improves the productivity of LC/MSMS

Analytical Sciences

Volumn 19, Issue 4, 2003, Pages 479-485

  Xie, Fuming ^a   Bruntlett, Craig S ^a   Zhu, Yongxin ^a   Kissinger, Candice B ^a   Kissinger, Peter T ^a  

^a BIOANALYTICAL SYSTEMS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; BLOOD PRESSURE; ELECTROPHYSIOLOGY; END EFFECTORS; LABORATORIES; MAMMALS; ROBOTICS;

BIOANALYTICAL CHEMISTRY; BIOLOGICAL FLUIDS; BLOOD-BRAIN BARRIER; DRUG-DRUG INTERACTIONS; LABORATORY ANIMALS; MICRODIALYSIS SAMPLING; RESEARCH PROGRAMS; SAMPLE PREPARATION;

DRUG INTERACTIONS;

BIOLOGICAL MARKER; CARBAMAZEPINE; NEW DRUG;

ACCURACY; ANALYTIC METHOD; ANIMAL BEHAVIOR; AUTOMATION; BLOOD BRAIN BARRIER; BLOOD PRESSURE; BLOOD SAMPLING; BODY FLUID; CARDIOLOGY; CATHETER; COMPUTER PROGRAM; DOG; DRUG ABSORPTION; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG METABOLISM; ELECTROPHYSIOLOGY; EXPERIMENTAL ANIMAL; HEMATOLOGY; INSTRUMENTATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MICRODIALYSIS; MOUSE; NONHUMAN; PRIMATE; PRODUCTIVITY; RAT; REVIEW; ROBOTICS;

EID: 0038218260     PISSN: 09106340     EISSN: None     Source Type: Journal    
DOI: 10.2116/analsci.19.479     Document Type: Review

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