The display of sexual behaviors by female rats administered ICI 182,780

Hormones and Behavior

Volumn 43, Issue 4, 2003, Pages 454-464

  Clark, Ann S ^a   Guarraci, Fay A ^a   Megroz, Alison B ^a   Porter, Donna M ^b   Henderson, Leslie P ^b  

^a Lamont Doherty Earth Observatory   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

Antiestrogen; Estrogen; Estrogen receptors; Paced mating behavior; Progesterone; Progestin receptors; Sexual receptivity

Indexed keywords

ANTIESTROGEN; ESTRADIOL BENZOATE; ESTROGEN; FULVESTRANT; PROGESTERONE; PROGESTERONE RECEPTOR;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; EJACULATION; ESTROGEN ACTIVITY; FEMALE; LATENT PERIOD; MALE; MATING; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN INDUCTION; RAT; SEXUAL BEHAVIOR; UTERUS; UTERUS WEIGHT;

EID: 0038209150     PISSN: 0018506X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0018-506X(03)00029-1     Document Type: Article

References (46)

1. Adler N.T., Davis P.G., Komisaruk B.R. Variation in the size and sensitivity of a genital sensory field in relation to the estrous cycle in rats. Horm. Behav. 9:1977;334-344.
2. Berkley K.J., Hoffman G.E., Murphy A.Z., Holdcroft A. Pain sex/gender differences. Pfaff D.W., Arnold A.P., Etgen A.M., Fahrbach S.E., Rubin R.T. Hormones, Brain and Behavior. Vol. V:2002;409-442 Academic Press, San Diego, CA.
3. Bermant G. Response latencies of female rats during sexual intercourse. Science. 133:1961;1771-1773.
4. Bermant G., Westbrook W.H. Peripheral factors in the regulation of sexual contact by female rats. J. Comp. Physiol. Psychol. 61:1966;244-250.
5. Blaustein J.D., Erskine M.S. Feminine sexual behavior cellular integration of hormonal and afferent information in the rodent forebrain . Pfaff D.W., Arnold A.P., Etgen A.M., Fahrbach S.E., Rubin R.T. Hormones, Brain and Behavior. Vol. 1:2002;139-214 Academic Press, San Diego, CA.
6. Bradshaw H.B., Berkley K.J. Estrogen replacement reverses ovariectomy-induced vaginal hyperalgesia in the rat. Maturitas. 41:2002;157-165.
7. Bradshaw H.B., Temple J.L., Wood E., Berkley K.J. Estrous variations in behavioral responses to vaginal and uterine distension in the rat. Pain. 82:1999;187-197.
8. Brandling-Bennett, E.M., Blasberg, M.E., Clark, A.S. 1999. Paced mating behavior in female rats in response to different hormone priming regimens. Horm. Behav., doi:10.1006/hbeh.1998.1507.
9. Clarke C.L., Zaino R.R., Feil P.D., Miller J.V., Steck M.E., Ohlsson-Wilhelm B.M., Satyaswaroop P.G. Monoclonal antibodies to human progesterone receptor characterization by biochemical and immunohistochemical techniques . Endocrinology. 121:1987;1123-1132.
10. Copas P., Bukovsky A., Asbury B., Elder R.F., Caudle M.R. Estrogen, progesterone, and androgen receptor expression in levator ani muscle and fascia. J. Women's Health Gender-Based Med. 10:2001;785-795.
11. DeFriend D.J., Howell A., Nicholson R.I., Anderson E., Dowsett M., Mansel R.E., Blamey R.W., Bundred N.J., Robertson J.F., Saunders C., Baum M., Walton P., Sutcliffe F., Wakeling A.E. Investigation of a new pure antiestrogen (ICI 182780) in women with primary breast cancer. Cancer Res. 54:1994;408-414.
12. Edwards D.A., Pfeifle J.K. Hormonal control of receptivity, proceptivity and sexual motivation. Physiol. Behav. 30:1983;437-443.
13. Emery D.E. Effects of endocrine state on sociosexual behavior of female rats tested in a complex environment. Behav. Neurosci. 100:1986;71-78.
14. Erskine M.S. Effects of paced coital stimulation on estrus duration in intact cycling rats and ovariectomized and ovariectomized-adrenalectomized hormone-primed rats. Behav. Neurosci. 99:1985;155-161.
15. Erskine M.S. Solicitation behavior in the estrous female rat a review . Horm. Behav. 23:1989;473-502.
16. Erskine M.S. Pelvic and pudendal nerves influence the display of paced mating behavior in response to estrogen and progesterone in the female rat. Behav. Neurosci. 106:1992;690-697.
17. Erskine M.S. Prolactin release after mating and genitosensory stimulation in females. Endocr. Rev. 16:1995;508-529.
18. Erskine M.S., Weaver C.E. The role of ovarian sympathetic innervation in the control of estrous responsiveness in the rat. Horm. Behav. 22:1988;1-11.
19. Gardener, H.E., Clark, A.S., 2001. Systemic ICI 182,780 alters the display of sexual behaviors in the female rat. Horm. Behav., doi:10.1006/hbeh.2000.1638.
20. Gomora P., Beyer C., Gonzalez-Mariscal G., Komisaruk B.R. Momentary analgesia produced by copulation in female rats. Brain Res. 656:1994;52-58.
21. Guarraci F.A., Megroz A.B., Clark A.S. The effects of ibotenic acid lesions of the nucleus accumbens on paced mating behavior in female rats. Behav. Neurosci. 116:2002;568-576.
22. Hardy D.F., DeBold J.F. The relationship between levels of exogenous hormones and the display of lordosis by the female rat. Horm. Behav. 2:1971;287-297.
23. Howell A., Osborne C.K., Morris C., Wakeling A.E. ICI 182,780 (Faslodex™) Development of a novel, "pure" antiestrogen . Cancer. 89:2000;817-825.
24. Komisaruk B.R. The nature of the neural substrate of female sexual behavior in mammals and its hormonal sensitivity review and speculations . Hutchinson J.B. Biological Determinants of Sexual Behavior. 1978;349-393 Wiley, New York.
25. Komisaruk B.R., Whipple B. Vaginal stimulation-produced analgesia in rats and women. Ann. NY Acad. Sci. 467:1986;30-39.
26. Kow L.-M., Pfaff D.W. Mapping of neural and signal transduction pathways for lordosis in search of estrogen actions on the central nervous system. Behav. Brain Res. 92:1998;169-180.
27. Kurita T., Lee K.-j., Saunders P.T.K., Cooke P.S., Taylor J.A., Lubahn D.B., Zhao C., Makela S., Gustafsson J.-A., Dahiya R., Cunha G.R. Regulation of progesterone receptors and decidualization in uterine stroma of the estrogen receptor-α knockout mouse. Biol. Reprod. 64:2001;272-283.
28. Luque E.H., Castro-Vazquez A. Sensory mechanisms involved in the induction of pseudopregnancy by progesterone increased sensitivity to stimulation of the pudendal sensory field . Endocrinology. 113:1983;385-390.
29. McClintock M.K., Adler N.T. The role of the female during copulation in wild and domestic Norway rats (Rattus norvegicus). Behaviour. 67:1978;67-96.
30. Ohta Y., Sato T., Iguchi T. Immunocytochemical localization of progesterone receptor in the reproductive tract of adult female rats. Biol. Reprod. 48:1993;205-213.
31. Parczyk K., Madjno R., Michna H., Nishino Y., Schneider M.R. Progesterone receptor repression by estrogens in rat uterine epithelial cells. J. Steroid Biochem. Mol. Biol. 63:1997;309-316.
32. Paredes R.G., Alonso A. Sexual behavior regulated (paced) by the female rat induces conditioned place preference. Behav. Neurosci. 111:1997;123-128.
33. Paredes R.G., Vazquez B. What do female rats like about sex? Paced mating. Behav. Brain Res. 105:1999;117-127.
34. Peirce J.T., Nuttall R.L. Self-paced sexual behavior in the female rat. J. Comp. Physiol. Psychol. 54:1961;310-313.
35. Robertson J.F., Nicholson R.I., Bundred N.J., Anderson E., Rayter Z., Dowsett M., Fox J.N., Gee J.M.W., Webster A., Wakeling A.E., Morris C., Dixon M. Comparison of the short-term biological effects of 7α-[9-(4,4,5,5,5-pentaflouropentylsulfinyl) nonyl] estra-1,3,5-(10)-triene-3,17β-diol versus tamoxifen in postmenopausal women with primary breast cancer. Cancer Res. 61:2001;6739-6746.
36. Robertson J.F.R. ICI 182,780 (Fulvestrant™) the first oestrogen receptor down-regulator: current clinical data . Br. J. Cancer. 85:(Suppl. 2):2001;11-14.
37. Shughrue P.J., Lane M.V., Scrimo P.J., Merchenthaler I. Comparative distribution of estrogen receptor-α (ER-α) and β (ER-β) mRNA in the rat pituitary, gonad, and reproductive tract. Steroids. 63:1998;498-504.
38. Thomas E.J., Walton P.L., Thomas N.M., Dowsett M. The effects of ICI 182,780, a pure anti-oestrogen, on the hypothalamic-pituitary-gonadal axis and on endometrial proliferation in pre-menopausal women. Hum. Reprod. 9:1994;1991-1996.
39. van der Schoot P., Baumgarten R. Interactions between oestradiol and the progesterone antagonist RU-486 in establishing and maintaining female rats' sexual responsiveness central versus peripheral effects . Behav. Brain Res. 47:1992;105-112.
40. Verheijen F.M., Sprong M., Jacobs H.M., Donker G.H., Amelink G.J., Thijssen J.H.H., Blankenstein M.A. Progesterone receptor isoform expression in human meningiomas. Eur. J. Cancer. 37:2001;1488-1495.
41. Wade G.N., Blaustein J.D., Gray J.M., Meredith J.M. ICI 182,780 a pure antiestrogen that affects behaviors and energy balance in rats without acting in the brain . Am. J. Physiol. 265:1993;R1392-R1398.
42. Wade G.N., Powers J.B., Blaustein J.D., Green D.E. ICI 182,780 antagonizes the effects of estradiol on estrous behavior and energy balance in Syrian hamsters. Am. J. Physiol. 265:1993;R1399-R1403.
43. Wakeling A.E., Dukes M., Bowler J. A potent specific pure antiestrogen with clinical potential. Cancer Res. 51:1991;3867-3873.
44. Xiao L., Becker J.B. Hormonal activation of the striatum and the nucleus accumbens modulates paced mating behavior in the female rat. Horm. Behav. 32:1997;114-124.
45. Yang L.-Y., Clemens L.G. Relation of intromissions to the female's postejaculatory refractory period in rats. Physiol. Behav. 60:1996;1505-1511.
46. Zipse L.R., Brandling-Bennett E.M., Clark A.S. Paced mating behavior in the naturally cycling and the hormone-treated female rat. Physiol. Behav. 70:2000;205-209.