Efficient synthesis of (R)- and (S)-1-amino-2,2-difluorocyclopropanecarboxylic acid via lipase-catalyzed desymmetrization of prochiral precursors

Tetrahedron Asymmetry

Volumn 14, Issue 12, 2003, Pages 1753-1761

  Kirihara, Masayuki ^a   Kawasaki, Masashi ^b   Takuwa, Tomofumi ^c   Kakuda, Hiroko ^c   Wakikawa, Takahiro ^c   Takeuchi, Yoshio ^c   Kirk, Kenneth L ^d  

^a SHIZUOKA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^b TOYAMA PREFECTURAL UNIVERSITY   (Japan)

^c UNIVERSITY OF TOYAMA   (Japan)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 AMINO 2,2 DIFLUOROCYCLOPROPANE CARBOXYLIC ACID; ACETOACETIC ACID; CARBOXYLIC ACID DERIVATIVE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ARTICLE; BURKHOLDERIA CEPACIA; CANDIDA ANTARCTICA; CHEMICAL REACTION; CONTROLLED STUDY; DRUG SYNTHESIS; ENANTIOMER; ENZYME DEGRADATION; NONHUMAN; PRIORITY JOURNAL;

EID: 0038205325     PISSN: 09574166     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0957-4166(03)00350-1     Document Type: Article

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