Antiviral Activity of Some 2′-Deoxyuridine 5-Arylethynyl Derivatives

Russian Journal of Bioorganic Chemistry

Volumn 29, Issue 3, 2003, Pages 262-266

  Andronova, V L ^a   Skorobogatyi, M V ^a   Manasova, E V ^b   Berlin, Yu A ^b   Korshun, V A ^b   Galegov, G A ^a  

^a D I IVANOVSKY INSTITUTE OF VIROLOGY   (Russian Federation)

^b SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

Author keywords

5 (3 perylenylethynyl) 2 deoxyuridine; 5 substituted 2 deoxyuridines; Antiviral activity; HSV 1; Type 1 herpes simplex virus

Indexed keywords

5 (1 PERYLENYLETHYNYL) 2' DEOXYURIDINE; 5 (3 PERYLENYLETHYNYL) 2' DEOXYURIDINE; 5 [4 (2 BENZOXAZOLYL)PHENYLETHYNYL] 2' DEOXYURIDINE; ANTIVIRUS AGENT; DEOXYURIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBIOTIC RESISTANCE; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; HERPES SIMPLEX VIRUS 1; NONHUMAN; VERO CELL; VIRUS REPLICATION; VIRUS STRAIN;

ANIMALIA; HUMAN HERPESVIRUS 1; SIMPLEXVIRUS;

EID: 0038201055     PISSN: 10681620     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1023936516589     Document Type: Article

References (18)

1. De Clercq, E., Meth. Find. Exp. Clin. Pharmacol., 1980, vol. 2, pp. 253-267.
2. Herdewijn, P.A.M.M., Antivir. Chem. Chemother., 1994, vol. 5, pp. 131-146.
3. De Clercq, E., Descamps, J., De Somer, P., Barr, P.J., Jones, A.S., and Walker, R.T., Proc. Natl. Acad. Sci. USA, 1979, vol. 76, pp. 2947-2951.
4. De Clercq, E., Descamps, J., Balzarini, J., Giziewicz, J., Barr, P.J., and Robins, M.J., J. Med. Chem., 1983, vol. 26, pp. 661-666.
5. McGuigan, C., Yarnold, C.J., Jones, G., Velázquez, S., Barucki, H., Brancale, A., Andrei, G., Snoeck, R., De Clercq, E., and Balzarini, J., J. Med. Chem., 1999, vol. 42, pp. 4479-4484.
6. McGuigan, C., Barucki, H., Blewett, S., Carangio, A., Erichsen, J.T., Andrei, G., Snoeck, R., De Clercq, E., and Balzarini, J., J. Med. Chem., 2000, vol. 44, pp. 4993-4997.
7. Korshun, V.A., Manasova, E.V., Balakin, K.V., Prokhorenko, I.A., Buchatskii, A.G., and Berlin, Yu.A., Bioorg. Khim., 1996, vol. 22, pp. 923-925.
8. Korshun, V.A., Manasova, E.V., Balakin, K.V., Malakhov, A.D., Perepelov, A.V., Sokolova, T.A., and Berlin, Yu.A., Nucleosides Nucleotides, 1998, vol. 17, pp. 1809-1812.
9. Malakhova, E.V., Malakhov, A.D., Kuznitsova, S.V., Varnavskii, O.P., Kadutskii, A.P., Kozhich, D.T., Korshun, V.A., and Berlin, Yu.A., Bioorg. Khim., 1998, vol. 24, pp. 688-695.
10. Malakhov, A.D., Malakhova, E.V., Kuznitsova, S.V., Grechishnikova, I.V., Prokhorenko, I.A., Skorobogatyi, M.V., Korshun, V.A., and Berlin, Yu.A., Bioorg. Khim., 2000, vol. 26, pp. 39-50.
11. Zieger, H.E., J. Org. Chem., 1966, vol. 31, pp. 2977-2981.
12. Classon, B. and Samuelsson, B., Acta Chem. Scand., 1985, vol. 39, pp. 501-504.
13. Robins, M.J. and Barr, P.J., J. Org. Chem., 1983, vol. 48, pp. 1854-1862.
14. Devadoss, C., Bharathi, P., and Moore, J.S., J. Am. Chem. Soc., 1996, vol. 118, pp. 9635-9644.
15. Galegov, G.A., Akberova, S.I., Andronova, V.L., Leont'eva, N.A., and Stroeva, O.G., Dokl. Ross. Akad. Nauk, 2000, vol. 373, pp. 404-407.
16. Galegov, G.A., Shobukhov, V.M., Leont'eva, N.A., and Yas'ko, M.V., Bioorg. Khim., 1997, vol. 23, pp. 906-909.
17. De Clercq, E., Descamps, J., Verheist, G., Walker, R.T., Jones, A.S., Torrence, P.F., and Shugar, D., J. Infect. Dis., 1980, vol. 141, pp. 563-573.
18. Lown, J.W., Krowicki, K., Balzarini, J., Newman, R.A., and De Clercq, E., J. Med. Chem., 1989, vol. 32, pp. 2368-2375.