Molecular cloning, genomic organization, chromosomal mapping and subcellular localization of mouse PAP7: A PBR and PKA-RIα associated protein

Gene

Volumn 308, Issue 1-2, 2003, Pages 1-10

  Liu, Jun ^a   Cavalli, Luciane R ^a   Haddad, Bassem R ^a   Papadopoulos, Vassilios ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Diazepam binding inhibitor; Golgi; Mitochondria; Mouse chromosome 1; Steroidogenesis

Indexed keywords

COMPLEMENTARY DNA; CYCLIC AMP DEPENDENT PROTEIN KINASE; DIAZEPAM BINDING INHIBITOR; LIGAND; PROTEIN; PROTEIN PAP7; UNCLASSIFIED DRUG;

AMINO ACID COMPOSITION; ANIMAL CELL; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CELLULAR DISTRIBUTION; CHROMOSOME 1; CHROMOSOME MAP; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME SUBUNIT; EXON; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE MAPPING; GENE SEQUENCE; GENETIC CONSERVATION; GENOME; GOLGI COMPLEX; HUMAN VERSUS ANIMAL COMPARISON; INTRON; LEYDIG CELL; MITOCHONDRION; MOLECULAR CLONING; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; STEROIDOGENESIS;

EID: 0038184148     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(03)00453-0     Document Type: Article

References (25)

1. Besman M.J., Yanagibashi K., Lee T.D., Kawamura M., Hall P.F., Shively J.E. Identification of des-(Gly-Ile)-endozepine as an effector of corticotropin-dependent adrenal steroidogenesis: Stimulation of cholesterol delivery is mediated by the peripheral benzodiazepine receptor. Proc. Natl. Acad. Sci. USA. 86:1989;4897-4901.
2. Boujrad N., Hudson J.R., Papadopoulos V. Inhibition of hormone-stimulated steroidogenesis in cultured Leydig tumor cells by a cholesterol-linked phosphorothioate oligodeoxynucleotide antisense to diazepam binding inhibitor. Proc. Natl. Acad. Sci. USA. 90:1993;5728-5731.
3. Boujrad N., Gaillard J.L., Garnier M., Papadopoulos V. Acute action of choriogonadotropin on Leydig tumor cells: induction of a higher affinity benzodiazepine-binding site related to steroid biosynthesis. Endocrinology. 135:1994;1576-1583.
4. Boujrad N., Vidic B., Papadopoulos V. Acute action of choriogonadotropin on Leydig tumor cells: changes in the topography of the mitochondrial peripheral-type benzodiazepine receptor. Endocrinology. 137:1996;5727-5730.
5. Costa E., Guidotti A. Diazepam binding inhibitor (DBI): a peptide with multiple biological actions. Life Sci. 49:1991;325-344.
6. Falquet L., Pagni M., Bucher P., Hulo N., Sigrist C.J., Hofmann K., Bairoch A. The PROSITE database, its status in 2002. Nucleic Acids Res. 30:2002;235-238.
7. Garnier M., Boujrad N., Ogwuegbu S.O., Hudson J.R. Jr, Papadopoulos V. The polypeptide diazepam-binding inhibitor and a higher affinity mitochondrial peripheral-type benzodiazepine receptor sustain constitutive steroidogenesis in the R2C Leydig tumor cell line. J. Biol. Chem. 269:1994;22105-22112.
8. Garnier M., Dimchev A.B., Boujrad N., Price J.M., Musto N.A., Papadopoulos V. In vitro reconstitution of a functional peripheral-type benzodiazepine receptor from mouse Leydig tumor cells. Mol. Pharm. 45:1994;201-211.
9. Gavish M., Bachman I., Shoukrun R., Katz Y., Veenman L., Weisinger G., Weizman A. Enigma of the peripheral benzodiazepine receptor. Pharmacol. Rev. 51:1999;629-650.
10. Golani I., Weizman A., Leschiner S., Spanier I., Eckstein N., Limor R., Yanai J., Maaser K., Scherubl H., Weisinger G., Gavish M. Hormonal regulation of peripheral benzodiazepine receptor binding properties is mediated by subunit interaction. Biochemistry. 40:2001;10213-10222.
11. Haddad B., Pabon-Pena C., Young H., Sun W.H. Fine mapping of STAT1 gene by FISH and radiation hybrids. Cytogenet. Cell Genet. 83:1998;58-59.
12. Higgins D.G., Thompson J.D., Gibson T.J. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22:1994;4673-4680.
13. Jefcoate C. High-flux mitochondrial cholesterol trafficking, a specialized function of the adrenal cortex. J. Clin. Invest. 110:2002;881-890.
14. Knudsen J., Hojrup P., Hansen H.O., Hansen H.F., Roepstorff P. Acyl-CoA-binding protein in the rat. Biochem. J. 262:1989;513-519.
15. Lacapère J.J., Delavoie F., Li H., Péranzi G., Maccario J., Papadopoulos V., Vidic B. Structural and functional study of reconstituted peripheral benzodiazepine receptor (PBR). Biochem. Biophys. Res. Commun. 284:2001;536-641.
16. Li H., Degenhardt B., Tobin D., Yao Z.X., Tasken K., Papadopoulos V. Identification, localization, and function in steroidogenesis of PAP7: a peripheral-type benzodiazepine receptor- and PKA (RIalpha)-associated protein. Mol. Endocrinol. 15:2001;2211-2228.
17. Li H., Yao Z., Degenhardt B., Teper G., Papadopoulos V. Cholesterol binding at the cholesterol recognition/interaction amino acid consensus (CRAC) of the peripheral-type benzodiazepine receptor and inhibition of steroidogenesis by an HIV TAT-CRAC peptide. Proc. Natl. Acad. Sci. USA. 98:2001;1267-1272.
18. McEnery M.W., Snowman A.M., Trifiletti R.R., Snyder S.H. Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier. Proc. Natl. Acad. Sci. USA. 89:1992;3170-3174.
19. Mujica A.O., Hankeln T., Schmidt E.R. A novel serine/threonine kinase gene, STK33, on human chromosome 11p15.3. Gene. 280:2001;175-181.
20. Papadopoulos V. Structure and function of the peripheral-type benzodiazepine receptor in steroidogenic cells. Proc. Soc. Exp. Biol. Med. 217:(2):1998;130-142.
21. Papadopoulos V., Berkovich A., Krueger K.E., Costa E., Guidotti A. Diazepam Binding Inhibitor (DBI) and its processing products stimulate mitochondrial steroid biosynthesis via an interaction with mitochondrial benzodiazepine receptors. Endocrinology. 129:1991;1481-1488.
22. Penotti F.E. Human pre-mRNA splicing signals. J. Theor. Biol. 150:(3):1991;385-420.
23. Sohda M., Misumi Y., Yamamoto A., Yano A., Nakamura N., Ikehara Y. Identification and characterization of a novel Golgi protein, GP60, that interacts with the integral membrane protein giantin. J. Biol. Chem. 276:2001;45298-45306.
24. Stocco D.M. Steroidogenic acute regulatory (StAR) protein: what's new? Bioessays. 21:1999;768-775.
25. Wilkins M.R., Lindskog I., Gasteiger E., Bairoch A., Sanchez J.-C., Hochstrasser D.F., Appel R.D. Detailed peptide characterization using PEPTIDEMASS - a World-Wide Web accessible tool. Electrophoresis. 18:(3-4):1997;403-408.