Toward a neuropsychological theory of antidepressant drug action: Increase in positive emotional bias after potentiation of norepinephrine activity

American Journal of Psychiatry

Volumn 160, Issue 5, 2003, Pages 990-992

  Harmer, Catherine J ^a,b   Hill, Simon A ^a   Taylor, Matthew J ^a   Cowen, Philip J ^a   Goodwin, Guy M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b WARNEFORD HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; NORADRENALIN; REBOXETINE; ADRENERGIC RECEPTOR AFFECTING AGENT; MORPHOLINE DERIVATIVE;

ADULT; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; EMOTION; EMOTIONAL STABILITY; FACIAL EXPRESSION; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; MEMORY; MOOD; NEUROPSYCHOLOGY; NORMAL HUMAN; PRIORITY JOURNAL; PSYCHOLOGICAL THEORY; RECOGNITION; AFFECT; BIOLOGICAL MODEL; CLASSIFICATION; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; DEFENSE MECHANISM; DEPRESSION; DOUBLE BLIND PROCEDURE; HAPPINESS; MIDDLE AGED; NEUROPHARMACOLOGY; NEUROPSYCHOLOGICAL TEST; PERCEPTIVE DISCRIMINATION; PERSONALITY; PSYCHOLOGICAL ASPECT; PSYCHOLOGICAL MODEL; RANDOMIZED CONTROLLED TRIAL;

ADRENERGIC UPTAKE INHIBITORS; ADULT; AFFECT; DEPRESSIVE DISORDER; DISCRIMINATION (PSYCHOLOGY); DOUBLE-BLIND METHOD; EMOTIONS; FACIAL EXPRESSION; FEMALE; HAPPINESS; HUMANS; MALE; MEMORY; MIDDLE AGED; MODELS, BIOLOGICAL; MODELS, PSYCHOLOGICAL; MORPHOLINES; NEGATIVISM; NEUROPHARMACOLOGY; NEUROPSYCHOLOGICAL TESTS; PERSONALITY;

EID: 0038182445     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/appi.ajp.160.5.990     Document Type: Article

References (9)

1. Schatzberg AF: Clinical efficacy of reboxetine in major depression. J Clin Psychiatry 2000; 61(suppl 10)31-38
2. Beck AT, Rush AJ, Shaw BF, Emery G: Cognitive Therapy of Depression. New York, Guilford, 1979
3. Peselow ED, Robins C, Block P, Barouche F, Fieve RR: Dysfunctional attitudes in depressed patients before and after clinical treatment and in normal control subjects. Am J Psychiatry 1990; 147:439-444
4. Harmer CJ, Bhagwagar Z, Perrett DI, Vollm BA, Cowen PJ, Goodwin GM: Acute SSRI administration affects the processing of social cues in healthy volunteers. Neuropsychopharmacology 2003; 28:148-152
5. Anderson NH: Likableness ratings of 555 personality-trait words. J Pers Soc Psychol 1968; 9:272-279
6. Rey A: L'examen de clinique en psychologie. Paris, Presses Universitaires de France, 1964
7. Reid IC, Stewart CA: How antidepressants work: new perspectives on the pathophysiology of depressive disorder. Br J Psychiatry 2001; 178:299-303
8. Kent JM, Coplan JD, Gorman JM: Clinical utility of the selective serotonin reuptake inhibitors in the spectrum of anxiety. Biol Psychiatry 1998; 44:812-824
9. Knutson B, Wolkowitz OM, Cole SW, Chan T, Moore EA, Johnson RC, Terpstra J, Turner RA, Reus VI: Selective alteration of personality and social behavior by serotonergic intervention. Am J Psychiatry 1998; 155:373-379