V1 neurons signal acquisition of an internal representation of stimulus location

Science

Volumn 300, Issue 5626, 2003, Pages 1758-1763

  Sharma, Jitendra ^a   Dragoi, Valentin ^a   Tenenbaum, Joshua B ^a   Miller, Earl K ^a   Sur, Mriganka ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; CELLS; NEURAL NETWORKS; VISION;

NEURONS;

NEUROLOGY;

BEHAVIOR; VISION;

ADULT; ANIMAL EXPERIMENT; ARTICLE; BAYES THEOREM; BEHAVIOR; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EYE; GAZE; HUMAN; HUMAN EXPERIMENT; MONKEY; NERVE CELL; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROBABILITY; RANDOMIZED CONTROLLED TRIAL; SIGNAL PROCESSING; STIMULUS LOCATION; STIMULUS RESPONSE; VISION; VISUAL CORTEX; VISUOMOTOR COORDINATION;

ANALYSIS OF VARIANCE; ANIMALS; BAYES THEOREM; CUES; ELECTROPHYSIOLOGY; FIXATION, OCULAR; HUMANS; MACACA MULATTA; NEURONS; PHOTIC STIMULATION; PROBABILITY; RANDOM ALLOCATION; SACCADES; VISUAL CORTEX; VISUAL PERCEPTION;

ANIMALIA;

EID: 0038179326     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1081721     Document Type: Article

References (38)

1. Materials and methods are available on Science Online.
2. A. W. F. Edwards, Likelihood (Cambridge Univ. Press, Cambridge, 1972).
3. R. H. S. Carpenter, M. L. Williams, Nature 377, 59 (1995).
4. , E. Kowler, in Eye Movements and Their Role in Visual and Cognitive Processes, E. Kowler, Ed. (Elsevier, Amsterdam, 1990), vol 4, chap. 1, pp. 1-63.
5. R. D. Luce, Response Times: Their Role in Inferring Elementary Mental Organization (Oxford, New York, 1986), pp. 253-268.
6. R. A. Andersen, Annu. Rev. Neurosci. 12, 377 (1997).
7. J. D. Schall, Nature Rev. Neurosci. 2, 33 (2001).
8. P. W. Glimcher, Trends Neurosci. 24, 654 (2001).
9. M. N. Shadlen, W. T. Newsome, J. Neurophysiol. 86, 1916 (2001).
10. M. E. Goldberg, J. Bisley, K. D. Powell, J. Gottlieb, M. Kusunoki, Ann. N.Y. Acad. Sci. 956, 205 (2002).
11. M. A. Sommer, R. H. Wurtz, Science 296, 1480 (2002).
12. J. Schlag, P. Dassonville, M. Schlag-Rey, J. Neurophysiol. 79, 64 (1998).
13. K. Toyama, Y. Komatsu, K. Shibuki, J. Neurophysiol. 51, 649 (1984).
14. T. G. Weyand, J. G. Malpeli, J. Neurophysiol. 69, 2258 (1993).
15. Y. Trotter, S. Celebrini, Nature 398, 239 (1999).
16. P. Rosenbluth, J. M. Allman, Neuron 33, 143 (2002).
17. P. M. Schiller, E. J. Tehovnik, Prog. Brain Res. 134, 127 (2001).
18. The cell of Fig. 2B similarly showed no change in the trial-by-triat IRI at the left and center gaze directions.
19. R. Lal, M. J. Friedlander, Science 243, 93 (1989).
20. P. R. Roelfsema, V. A. Lamme, H. Spekreijse, Nature 395, 376 (1998).
21. D. C. Somers, A. M. Date, A. E. Seiffert, R. B. H. Tootell, Proc. Natl. Acad. Sci. U.S.A. 96, 1663 (1999).
22. M. I. Posner, C. D. Gilbert, Proc. Natl. Acad. Sci. U.S.A. 96, 2585 (1999).
23. R. B. H. Tootell, N. Hadjikhani, Nature Neurosci. 3, 206 (2000).
24. A. Schoups, R. Vogels, N. Qian, G. A. Orban, Nature 412, 549 (2001).
25. C. D. Gilbert, M. Sigman, R. E. Crist, Neuron 31, 681 (2001).
26. D. Ress, D. J. Heeger, Nature Neurosci. 6, 414 (2003).
27. P. A. Salin, J. Buttler, Physiol. Rev. 75, 107 (1995).
28. D. J. Felleman, D. C. Van Essen, Cereb. Cortex 1, 1 (1991).
29. D. C. Lyon, J. H. Kaas, Neuron 33, 453 (2002).
30. R. A. Andersen, G. K. Essick, R. M. Siegel, Science 230, 456 (1985).
31. R. J. Krauzlis, C. S. Stone, Trends Neurosci. 22, 544 (1999).
32. C. L Colby, J. R. Duhamel, M. E. Goldberg, Cereb. Cortex 5, 470 (1995).
33. K. Nakamura, C. L. Colby, Proc. Natl. Acad. Sci. U.S.A. 99, 4026 (2002).
34. S. Ben Hamed, J. R. Duhamel, Exp. Brain Res. 142, 512 (1998).
35. B. Gaymard, C. J. Ploner, S. Rivaud, A. I. Vermersch, C. Pierrot-Deseilligny, Exp. Brain Res. 123, 159 (1998).
36. D. C. Somers, S. B. Nelson, M. Sur, J. Neurosci. 15, 5448 (1995).
37. V. Dragoi, J. Sharma, E. K. Miller, M. Sur, Nature Neurosci., 5, 883 (2002).
38. We thank P, Sinha for insightful discussions and comments and J. Schummers, J. Mariño, B. Scott, and D. Lyon for careful reading of the manuscript and suggestions. Supported by a fellowship from the McDonnell-Pew Foundation (V.D.) and grants from NIH (M.S.).