Hypoglycemic properties of Viscum album (Mistletoe) in alloxan-induced diabetic animals

Pharmaceutical Biology

Volumn 41, Issue 3, 2003, Pages 184-187

  Ohiri, F C ^a   Esimone, C O ^a   Nwafor, S V ^a   Okoli, C O ^a   Ndu, O O ^a  

^a UNIVERSITY OF NIGERIA   (Nigeria)

Author keywords

Acute toxicity; Alloxan; Diabetes; Hypoglycemic effects; Loranthaceae; Mice; O toluidine method; Rabbits; Rats; Tolbutamide; Viscum album Stapf

Indexed keywords

ALLOXAN; VISCUM ALBUM EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIABETES MELLITUS; DOSE RESPONSE; FEMALE; GLUCOSE BLOOD LEVEL; HYPOGLYCEMIA; MALE; MOUSE; NONHUMAN; RABBIT; RAT; VISCUM ALBUM;

ANIMALIA; LORANTHACEAE; ORYCTOLAGUS CUNICULUS; VISCUM; VISCUM ALBUM;

EID: 0038163572     PISSN: 13880209     EISSN: None     Source Type: Journal    
DOI: 10.1076/phbi.41.3.184.15098     Document Type: Article

References (23)

1. Akah PA, Okafor CL (1992): Blood sugar lowering effect of Vernonia amygdalina Del. in experimental rabbit model. Phytotherapy Res 6: 171-173.
2. Bauer JD, Ackermann PA, Toro G (1974): Clinical Laboratory Methods, St. Louis, C.V. Mosby, pp. 383-386.
3. Evans WC (1989a): Trease and Evans Pharmacognosy. 13th ed., London, Bailieré Tindall, p. 171.
4. Evans WC (1989b): Trease and Evans Pharmacognosy. 13th ed., London, Bailieré Tindall, pp. 315-679.
5. Ezeugwu CO, Nze IC (1998): Alternative approaches to the management of diabetes mellitus - A review. Nig J Pharm Practice and Continuing Educ 1: 6-17.
6. Gavril N, Corneal B (1970): Chemotaxonnomic studies on higher plants III. Carotenoids of Viscum album. Plant Biochem 13: 59-63.
7. Hans B, Joechim E, Gernard S (1979): Isolation and identification of 2-hydroxy-4,6-dimethoxy chalcone-4-glycoside of Viscum album II. Plant Biochem 90: 313.
8. Hardy KJ, McNutty SJ (1997): Oral hypoglycemic agents. Medicine Digest 23(4): 5-9.
9. Iwu MM (1980): Antidiabetic properties of Bridelia ferruginea leaves. Planta Med 39: 247.
10. Iwu MM, Okunji CO, Akah PA, Tempesta MS, Corley DG (1990): Diocoretine: the hypoglycemic principle of Dioscorea dumentorum. Planta Med 56: 119-120.
11. Jackson JE, Bressler R (1981): Clinical pharmacology of sulphonylurea hypoglycemic agents, Part 1. Drugs 22: 211-245.
12. Janssen O, Scheffler A, Kabelitz D (1993): In vitro effects of mistletoe extracts and mistletoe lectins: cytotoxicity towards tumor cells due to the induction of programmed cell death (apoptosis). Fortschritte der Arzheimittel forschung. Progress in Drug Research 43: 1221-1227.
13. Jung ML, Baudino S, Ribereau-Gayon G (1990): Characterization of cytotoxic proteins from mistletoe (Viscum album L.). Cancer Letters 51: 103-108.
14. Kafaru E (1994): Immense Health from Nature's Workshop. 1: 34, 54.
15. Kapeham SM (1997): Drugs from Natural Products - Plant Sources in Drug Discovery, Science and Development. Washington DC, American Chemical Society, p. 6.
16. Krzaczek T (1976): Pharmacobotanical studies of the sub-species of Viscum album L II. Saccharides 31: 281-290.
17. Krzaczek T (1977): Pharmacobotanical studies of the sub-species of Viscum album L III. Terpenes and Sterols 32: 125-134.
18. Lorke D (1983): A new approach to practical acute toxicity. Arch Toxicol 53: 275-289.
19. Nada SA, Baskandy SAE, Negm SA (1997): Evaluation of the hypoglycaemic activity of a traditional herbal preparation in male diabetic rats. Fitoterapia 68: 240-244.
20. Popova OI, Muravava DA (1995): Examining the components of mistletoe (Viscum album). Lipids 44: 12-15.
21. Skim F, Kaaya A, Jaouari JT, Lazrek HB (1999): Hypoglycemic activity of Globularia alypum leaves in rats. Fitoterapia 70: 382-389.
22. Undie AS, Akubue PI (1986): Pharmacological evaluation of Dioscorea dumentorum tuber used in traditional anti-diabetic therapy. J Ethnopharmacol 15: 133-144.
23. Zarrow MX, Yochim JM, McCarthy JL (1964): Experimental Endocrinology: A Source Book of Basic Techniques. New York, Academic Press, 406-409.