The effect of a strongly basic alkaloidal fraction of Rhazya stricta, a traditional medicinal plant, on cytochrome P450-mediated metabolism of theophylline in mice

Phytotherapy Research

Volumn 17, Issue 6, 2003, Pages 688-690

  El Kadi, A O ^b   Tanira, M O M ^b   Ali, B H ^a   Bashir, A K ^b   Du Souich, P ^b  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b NONE

Author keywords

Cytochrome P450; Metabolism; Mouse; Rhazya stricta; Theophylline

Indexed keywords

ALKALOID; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 ISOENZYME; RHAZYA STRICTA EXTRACT; THEOPHYLLINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; CATALYSIS; CONTROLLED STUDY; DRUG METABOLISM; DRUG TRANSFORMATION; LIVER HOMOGENATE; LIVER MICROSOME; MALE; MOUSE; NONHUMAN; PLANT; RHAZYA STRICTA; TRADITIONAL MEDICINE;

ADMINISTRATION, ORAL; ANIMALS; APOCYNACEAE; CYTOCHROME P-450 ENZYME SYSTEM; DRUG INTERACTIONS; MALE; MICE; MICROSOMES, LIVER; PHYTOTHERAPY; PLANT EXTRACTS; THEOPHYLLINE;

ANIMALIA; RHAZYA; RHAZYA STRICTA;

EID: 0038124761     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1224     Document Type: Article

References (13)

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