Isolation and physiopharmacological properties of three high molecular weight lethal proteins from a coelenterate (Physalia utriculus) venom

Pakistan Journal of Zoology

Volumn 28, Issue 3, 1996, Pages 245-252

  Alam, Junaid Mahmood ^a,b   Qasim, Rashida ^a  

^a UNIVERSITY OF KARACHI   (Pakistan)

^b Toxiclone 8B/I   (Pakistan)

Author keywords

Jellyfish; Lethal proteins; Venom

Indexed keywords

EID: 0038110527     PISSN: 00309923     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. ALAM, J.M. AND QASIM, R., 1991. Toxicology of Physalia (Portuguese man-of-war) venom. Pakistan J. Pharmceut. Sci., 4: 159-168.
2. ALAM, J.M. AND QASIM, R. 1992. Preliminary siudies on the biological and hazardous marine toxins from Karachi coast: (1) biochemical and biological properties of Physalia venom. Toxicon, 30: 532.
3. ALAM, J.M. AND QASIM, R., 1993a. Changes in serum components induced by venoms of marine animals. Pakistan J. Pharmaceut. Sci., 6: 81-88.
4. ALAM, J.M. AND QASIM. R., 1993b. Preliminary studies on the biological and hazardous marine toxins from Karachi coast: (III) biochemical and biological properties of a high molecular weight hemolytic and toxic protein from Physalia venom. Proc. First Intl. Conf. Pharmaceu., Sci., Karachi-1992 (ed Z.S. Saify), pp. 15-20. BCC and T Press, Karachi.
5. ALAM, S.M., JAMAL, Q., IQBAL, N. AND ALAM, J.M., 1992. Effects of marine toxins on albino rats. J. Coll. Phys. Surg. Pakistan, 2: 73-78.
6. ALAM, J.M., ALAM, S.M. AND OASIM, R., 1993. Pathogenesis of the morphological lesions in various organs in guinea pigs produced by cytotoxic compounds from marine animals. Pakistan J. Path., 4: 95-99.
7. AZILA, N. AND OTHMAN, I., 1993. Cases of jellyfish envenomation in Malaysia and some cytotoxic studies of their toxins. In: Advances in venom and toxin research (eds. N.H. Tan, S.L.OO., V., Thambyrajah and N. Azila), pp. 113-118. Malaysian Society of Toxicology, Malaysia.
8. BURNETT, J.W. AND CALTON, G.T., 1974a. The enzymatic content of the venoms of the nea netlle and Portuguese man-of-war. Toxicon, 47: 815-820.
9. BURNETT, J.W. AND CALTON, G.J., 1974b. Sea netlle and Portuguese man-of-war venoms: a chemical comparison of their venoms and studies on the pathogenesis of the sting. J. Invest. Dermatol., 62: 372-277.
10. BURNETT, J.W. AND CALTON, G.J., 1977. Review article: The chemistry and toxicology of some venomous pelagic coelcnterate. Toxicon, 15: 177-196.
11. BURNETT, J.W. AND GABLE, W.D., 1989. A fatal jellyfish envenomation by Portuguese man-of-war. Toxicon, 27: 823-824.
12. CALTON, G.J. AND BURNETT J.W., 1973. The purification of Portuguese man-of-war nematocyst toxins by gel diffusion. Comp. Gen. Pharm., 4: 267-270.
13. CARIELLO L., GIONANNA, R., SPAGNUOLO, A. AND ZANETTI, L., 1988. Isolation and partial characterization of rhizolysin, a high molecular weight protein with hemolytic activity, from the jellyfish, Rhiznstoma pulmo. Toxicon, 26: 19576-1965.
14. CRUZ, L.J., 1977. A quantitative assay for Conus toxin. Acta Med. Philippina, 13: 13-16.
15. ENDEAN, R., DUCHEMIN, C., McLOM, D. AND FRASER, E.H., 1969. A study of the biological activity of toxic material derived from nematocysts of the cubomedusan, Chironex fleckeri. Toxicon, 6: 179-204.
16. LAEMMLI, U.K., 1970. Cleavage of structural proteins during assembly of the head of bacteriophage T4 Nature, 227: 680-685.
17. LONG, K.O. AND BURNETT, J.W., 1989. Isolation, characterization and comparison of hemolytic peptides in nematocyst venoms of two species of jellyfish (Chrysaora quinquecirrha and Cyanea capillata). Comp. Biochem. Physiol., 94: 641-646.
18. MENENDEZ, R., MAS, R., GARATEIX, A,. GARCIA, M. AND CHAVEZ, M., 1990. Effects of a high molecular weight polypeptide toxin from Physalia physalis (Portuguese man-of-war) on cholinergic responses. Comp. Biochem. Physiol., 95: 63-69.
19. MINTON, Jr. S.A., 1974. Venomous Marine Invertebrates. In: Venom diseases (ed. N. Kugclmass), pp 3-26, Charles C Thomas Publisher, Springfield.
20. OTHMAN, I. AND BURNETT, J.W., 1990. Techniques applicable for purifying Chironex fleckeri (Box jellyfish) venom. Toxicon, 28: 821-835.
21. ROSENBERG., P., 1978. Toxins. Animals, plants and microbial. Pergamon Press New York.
22. RUSSELL, F.E., 1965. Marine toxins and venomous and poisonous marine animals. In: Advances in marine biology (ed. F.S. Russell), vol. 3. Academic Press. London.
23. RUSSELL, P.E., 1984. Marine toxins and venomous and poisonous marine animals. In: Advances in marine biology (eds. J.H.S. Blaxter, F.S. Russell and C.M. Yonge), Academic Press, London.
24. STEIN, M.R., MARRACCINI, J.V., ROTHISCHILD, N.E. AND BURNETT, J.W., 1989. Fatal Portuguese man-of-war (Physalis) envenomation. Annl. Emerg. Med., 18: 312-315.
25. TAMKUN, M.M. AND HESSINGER, D.A, 1981. Isolation and partial purification of a hemolytic and toxic protein from the nematocyst venom of the Portuguese man-of-war, Physalia physalis. Biochim. Biophys. Acta, 667: 87-98.
26. WILLIAMSON, J.A., 1990. Cases of Physalia envenomation, In: Some Australian and international. Marine Envenomation Reports: Progress Summary to Nov. 1990, pp. 4 ICJS-Newsletter: Australia.