The application of immunohistochemical findings in the diagnosis in methamphetamine-related death-two forensic autopsy cases

Journal of Medical Investigation

Volumn 50, Issue 1-2, 2003, Pages 112-116

  Ishigami, Akiko ^a   Kubo, Shin ichi ^a   Gotohda, Takako ^a   Tokunaga, Itsuo ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Immunohistochemistry; Kidney; Methamphetamine; Myoglobin; The 70 kDa heat shock protein

Indexed keywords

HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 70 ANTIBODY; METHAMPHETAMINE; MYOGLOBIN; MYOGLOBIN ANTIBODY; PROTEIN ANTIBODY; UNCLASSIFIED DRUG; BIOLOGICAL MARKER;

ADULT; ANTIBODY DETECTION; ARTICLE; AUTOPSY; BLOOD LEVEL; BRONCHUS; CADAVER; CASE REPORT; CAUSE OF DEATH; FORENSIC PATHOLOGY; HUMAN; HUMAN TISSUE; HYPERTHERMIA; IMMUNOHISTOCHEMISTRY; INTOXICATION; LETHAL DOSE; LUNG CONGESTION; MALE; MUSCLE CONTRACTION; RECTUM TEMPERATURE; SKELETAL MUSCLE; TOXICOLOGICAL PARAMETERS; TRACHEA; ACUTE KIDNEY FAILURE; ANALYTICAL EQUIPMENT; BLEEDING; CHEMICALLY INDUCED DISORDER; CHEMISTRY; FEMALE; FEVER; FLUORESCENT ANTIBODY TECHNIQUE; FORENSIC MEDICINE; KIDNEY; KIDNEY TUBULE ACIDOSIS; LUNG EDEMA; PATHOLOGY; RHABDOMYOLYSIS; STAINING; STOMACH JUICE; SUDDEN DEATH;

BRONCHUS;

ACIDOSIS, RENAL TUBULAR; ADULT; AUTOPSY; BIOLOGICAL MARKERS; DEATH, SUDDEN; FEMALE; FEVER; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; FORENSIC MEDICINE; GASTROINTESTINAL CONTENTS; HEMORRHAGE; HSP70 HEAT-SHOCK PROTEINS; HUMANS; KIDNEY; KIDNEY FAILURE, ACUTE; MALE; METHAMPHETAMINE; MUSCLE, SKELETAL; MYOGLOBIN; PULMONARY EDEMA; REAGENT KITS, DIAGNOSTIC; RHABDOMYOLYSIS; STAINING AND LABELING;

EID: 0038100304     PISSN: 13431420     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Uchima E: Physiologic studies on acute methamphetamine poisoning. Jpn J Legal Med (in Japanese) 38: 814-826, 1984
2. Nagata T: Signification of methamphetamine concentration in body fluids and tissues. Jpn J Legal Med (in Japanese) 37: 513-518, 1983
3. rd edition. Charles C Thomas, Springfield, 1993, pp. 733-766
4. He SY, Matoba R, Fujitani N, Sodesaki K, Onishi S: Cardiac muscle lesions associated with chronic administration of methamphetamine in rats. Am J Forensic Med Pathol 17: 155-162, 1996
5. Karch SB, St ephens BG, Ho CH: Methamphetamine-related deaths in San Francisco: demographic, pathologic, and toxicologic profiles. J Forensic Sci 44: 359-368, 1999
6. Investigation committee of the Medico-Legal Society of Japan: Reports on medico-legal data from massive investigation performed by the Medico-Legal Society of Japan-weight and size of internal organs of normal Japanese today-. Jpn J Legal Med 46: 225-235, 1992
7. Methamphetamine. (1) Gas chromatography, and gas chromatography-mass spectrometry. In: Working group for forensic toxicology, ed. Manual for forensic toxicology analysis of the Japanese Society of Legal Medicine. 1999, pp.26-29
8. Richards JR: Rhabdomyolysis and drugs of abuse. J Emerg Med 19: 51-56, 2000
9. Kendrick WC, Hull AR, Knochel JP: Rhabdomyolysis and shock after intravenous amphetamine administration. Ann Intern Med 86: 381-387, 1977
10. Richards JR, Johnson EB, Stark RW, Derlet RW: Methamphetamine abuse and rhabdomyolysis in the ED: a 5-year study. Am J Emerg Med 17: 681-685, 1999
11. Terada Y, Shinohara S, Matui N, Ida T: Amphetamine-induced myoglobinuric acute renal failure. Jpn J Med 27: 305-308, 1988
12. Ramcharan S, Meenhorst PL, Otten JM, Koks CH, de Boer D, Maes RA, Beijnen JH: Survival after massive ecstasy overdose. J Toxicol Clin Toxicol 36: 727-731, 1998
13. Lan KC, Lin YF, Yu FC, Lin CS, Chu P: Clinical manifestations and prognostic features of acute methamphetamine intoxication. J Formos Med Assoc 97: 528-533, 1998
14. Holt S, Moore K: Pathogenesis of renal failure in rhabdomyolysis: the role of myoglobin. Exp Nephrol 8: 72-76, 2000
15. Lu D, Das DK: Induction of differential heat shock gene expression in heart, lung, brain and kidney by a sympathomimetic drug, amphetamine. Biochem Biophys Res Commun 192: 808-812, 1993
16. Venkataseshan VS, Marquet E: Heat shock protein 72/73 in normal and diseased kidneys. Nephron 73: 442-449, 1996
17. Kuperman DI, Freyaldenhoven TE, Schmued LC, Ali SF: Methamphetamine-induced hyperthermia in mice: examination of dopamine depletion and heat-shock protein induction. Brain Res 771: 221-227, 1997
18. Chen HC, Guh JY, Tsai JH, Lai YH: Induction of heat shock protein 70 protects mesangial cells against oxidative injury. Kidney Int 56: 1270-1273, 1999
19. Jayakumar J, Suzuki K, Sammut IA, Smolenski RT, Khan M, Latif N, Abunasra H, Murtuza B, Amrani M, Yacoub MH: Heat shock protein 70 gene transfection protects mitochondrial and ventricular function against ischemia-reperfusion injury. Circulation 104 (Suppl I): I303-I307, 2001
20. Zhu BL, Ishida K, Quan L, Taniguchi M, Oritani S, Kamikodai Y, Fujita MQ, Maeda H: Post-mortem urinary myoglobin levels with reference to the causes of death. Forensic Sci Int 115: 183-188, 2001