Reduced circulating androgen bioactivity in patients with prostate cancer

Prostate

Volumn 55, Issue 3, 2003, Pages 194-198

  Raivio, Taneli ^a   Santti, Henrikki ^a   Schatzl, Georg ^d   Gsur, Andrea ^d   Haidinger, Gerald ^d   Palvimo, Jorma J ^a,b   Jänne, Olli A ^a,c   Madersbacher, Stephan ^d  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Androgen bioassay; Androgens; Benign prostatic hyperplasia; Prostate cancer; Testosterone

Indexed keywords

ANDROGEN; TESTOSTERONE;

ADULT; AGED; ANDROGEN BLOOD LEVEL; ANDROGEN METABOLISM; ARTICLE; BIOASSAY; CANCER RISK; CAUCASIAN; CONTROLLED STUDY; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE HYPERTROPHY; TESTOSTERONE BLOOD LEVEL; TUMOR VOLUME;

AGED; ANDROGENS; CARCINOMA; CASE-CONTROL STUDIES; HUMANS; MALE; MIDDLE AGED; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC HYPERPLASIA; PROSTATIC NEOPLASMS; SEX HORMONE-BINDING GLOBULIN; TESTOSTERONE;

EID: 0038077155     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/pros.10234     Document Type: Article

References (21)

1. Elo JP, Visakorpi T. Molecular genetics of prostate cancer. Ann Med 2001;33:130-141.
2. Abate-Shen C, Shen MM. Molecular genetics of prostate cancer. Genes Dev 2000;14:2410-2434.
3. Chan JM, Stampfer MJ, Giovannucci EL. What causes prostate cancer? A Brief summary of the epidemiology. Semin Cancer Biol 1998;8:263-273.
4. Taplin ME, Ho S-M. The endocrinology of prostate cancer. J Clin Endocrinol Metab 2001;86:3467-3477.
5. Bosland MC. The role of steroid hormones in prostate carcinogenesis. J Natl Cancer Inst Monogr 2000;27:39-66.
6. Toppari J, Skakkebaek NE. Sexual differentiation and environmental endocrine disrupters. Bailliere's Clin Endocrinol Metab 1998;12:143-156.
7. Hammond GL, Kontturi M, Määttälä P, Puukka M, Vihko R, Serum FSH, LH and prolactin in normal males and patients with prostatic diseases. Clin Endocrinol 1977;7:129-135.
8. Hilz H, Graefen M, Noldus J, Hammerer P, Knabbe C, Huland E, Huland H. Advanced prostate cancer is associated with a decrease in serum luteinizing hormone. Eur Urol 2000;38:43-249.
9. Schatzl G, Madersbacher S, Thürridl T, Waldmüller J, Kramer G, Haitel A, Marberger M. High-grade prostate cancer is associated with low serum testosterone levels. Prostate 2001;47:52-58.
10. Meikle AW, Smith JA, Stringham JD. Production, clearance, and metabolism of testosterone in men with prostatic cancer. Prostate 1987;10:25-31.
11. Miller LR, Partin AW, Chan DW, Bruzek DJ, Dobs AS, Epstein JI, Walsh PC. Influence of radical prostatectomy on serum hormone levels. J Urol 1998;160:449-453.
12. Raivio T, Palvimo JJ, Dunkel L, Wickman S, Jänne OA. Novel assay for determination of androgen bioactivity in human serum. J Clin Endocrinol Metab 2001;86:1539-1544.
13. Gsur A, Bernhofer G, Hinteregger S, Haidinger G, Schatzl G, Madersbacher S, Marberger M, Vutuc C, Micksche M. A polymorphism in the CYP17 gene is associated with prostate cancer risk. Int J Cancer 2000;87:434-437.
14. Schatzl G, Gsur A, Bernhofer G, Haidinger G, Hinteregger S, Vutuc C, Haitel A, Micksche M, Marberger M, Madersbacher S. Association of vitamin D receptor and 17 hydroxylase gene polymorphisms with benign prostatic hyperplasia and benign prostatic enlargement. Urology 2001;57:567-572.
15. Schatzl G, Reiter WJ, Thürridl T, Waldmüller J, Roden M, Söregi S, Madersbacher S. Endocrine patterns in patients with benign and malignant prostatic diseases. Prostate 2000;44:219-224.
16. Gleason DF. Histologic grading of prostate cancer: A perspective. Hum Pathol 1992;23:273-279.
17. Kuwahara A, Kamada M, Irahara M, Naka O, Yamashita T, Aono T. Autoantibody against testosterone in a woman with hypergonatropic hypogonadism. J Clin Endocrinol Metab 1998;83: 14-16.
18. Raivio T, Tapanainen JS, Kunelius P, Jänne OA. Serum androgen bioactivity during 5α-dihydrotestosterone treatment of elderly men. J Androl 2002; (In Press).
19. Liao S, Witte D. Autoimmune anti-androgen-receptor antibodies in human serum. Proc Natl Acad Sci USA 1985;82:8345-8348.
20. Stamey TA, McNeal JE. Adenocarcinoma of the prostate. In: Walsh PC, Retik AB, Stamey TA, Vaughan ED, editors. Campbell's Urology 6th edn. Philadelphia: W.B. Saunders; 1992. p 1159-1221.
21. Frydenberg M, Stricker PD, Kaye KW. Prostate cancer diagnosis and management. Lancet 1997;349:1681-1687.