Evaluation of a new fully automated one-step C-peptide chemiluminescence assay (LIAISON® C-Peptid)

Clinical Laboratory

Volumn 49, Issue 5-6, 2003, Pages 227-232

  Pfützner, Andreas ^a,b   Löbig, Mirjam ^a   Fortunato, Antonio ^c   Forst, Thomas ^a  

^a Institute for Clinical Research and Development   (Germany)

^b UNIVERSITY OF APPLIED SCIENCES   (Germany)

^c SAN BORTOLO HOSPITAL   (Italy)

Author keywords

C peptide; Chemiluminescence assay; LIAISON

Indexed keywords

AMINO ACID; BIOLOGICAL MARKER; C PEPTIDE; PROINSULIN;

ADULT; AGED; ARTICLE; AUTOMATION; CELL FUNCTION; CHEMOLUMINESCENCE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DIABETES MELLITUS; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; FACTITIOUS DISEASE; FEMALE; HUMAN; HYPOGLYCEMIA; INSULIN RELEASE; INSULINOMA; INTERMETHOD COMPARISON; MALE; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET BETA CELL; PROTEIN DETERMINATION; RADIOIMMUNOASSAY; SENSITIVITY AND SPECIFICITY; STANDARD;

BIOLOGICAL MARKERS; C-PEPTIDE; CHEMILUMINESCENT MEASUREMENTS; DIAGNOSTIC TECHNIQUES, ENDOCRINE; FEMALE; HUMANS; IMMUNOASSAY; MALE; MIDDLE AGED; REFERENCE VALUES; REPRODUCIBILITY OF RESULTS;

EID: 0038073035     PISSN: 14336510     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Steiner DF, Cunningham D, Spigelman L, Aten B. Insulin biosynthesis: evidence for a precursor. Science 1967, 157:697-700
2. Oyer PE, Cho S, Peterson JD, Steiner DF. Studies on human proinsulin. Isolation and amino acid sequence of the human pancreatic C-peptide. J Biol Chem 1971, 246:1375-1386
3. Kuzuya H, Blix PM, Horwitz DL, Steiner DF, Rubenstein AH. Determination of free and total insulin and C-peptide in insulin-treated diabetics. Diabetes 1977, 26:22-29
4. Polonsky KS, Rubenstein AH. C-peptide as a measure of the secretion and hepatic extraction of insulin. Pitfalls and limitations. Diabetes 1984, 33:486-494
5. Pfützner A, Lang JK, Eiermann DF. Assay of free insulin in serum of IDDM patients: performance of a PEG precipitation technique in conjunction with an ultrasensitive human insulin RIA with regular human insulin and lipidic carriers. Clin Lab 1999, 45:487-492
6. Forst T, Kunt T, Pohlmann T, Goitom K, Engelbach M, Beyer J, Pfützner A. Biological activity of C-peptide on the skin microcirculation in patients with insulin-dependent diabetes mellitus. J Clin Invest 1998, 101:2036-2041
7. Forst T, Kunt T, Pfützner A, Beyer J, Wahren J. New aspects on biological activity of C-peptide in IDDM patients. Exp Clin Endocrinol Diabetes 1998, 106:270-276
8. Kunt T, Schneider S, Pfützner A, Goitom K, Engelbach M, Schauf B, Beyer J, Forst T. The effect of human proinsulin C-peptide on erythrocyte deformability in patients with Type 1 diabetes mellitus. Diabetologia 1999, 42:465-471
9. Liljenquist JE, Horwitz DL, Jennings AS, Chiasson JL, Keller U, Rubenstein AH. Inhiibition of insulin secretion by exogenous insulin in normal man as demonstrated by C-peptide assay. Diabetes 1978, 27:563-570
10. Bonser AM, Garcia-Webb P. C-peptide measurement: methods and clinical utility. Crit Rev Clin Lab Sci 1984, 19:297-352
11. Service FJ, Rizza RA, Zimmerman BR, Dyck PJ, O'Brien PC, Melton U. The classification of diabetes by clinical and C-peptide criteria. A prospective population-based study. Diabetes Care 1997, 20:198-201
12. Cha T, Tahara Y, Ikegami H et al. Urinary C-peptide as an index of unstable glycemic control in insulin-dependent diabetes mellitus (IDDM). Diabetes Res Clin Pract 1991, 13:181-187
13. Lunell NO, Persson B, Viktorin L. Urinary C-peptide in gestational diabetes. S Afr Med J 1992, 81:147-149
14. Nauck MA, Braun F, Seidensticker F, Roder M, Dinesen B, Creutzfeldt WA. A hyperinsulinaemic sequentially eu- and hypoglycaemic clamp test to characterize autonomous insulin secretion in patients with insulinoma. Eur J Clin Invest 1997, 27:109-115
15. Nauck MS, Nauck MA, Nauck MA, März W, Wieland H. Six methods for the determination of C-peptide evaluated. Clin Chem Lab Med 1999, 37:745-752
16. Ricós C, Arbós MA. Quality goals for hormone testing. Ann Clin Biochem 1990, 27:353-358
17. Passing H, Bablok W. Comparison of several regression procedures for method comparison studies and determination of sample sizes. Application of linear regression procedures for method comparison studies in clinical chemistry, Part II. J Clin Chem Clin Biochem 1984, 22:431-445
18. Hardy RW, Cohn M, Konrad RJ. Automated chemiluminescent assay for C-peptide. J Clin Lab Anal 2000, 14:17-19
19. Stickle DF, McNeil SE. Evaluation of use of singleton measurements of C-peptide by RIA. Clin Chim Acta 1999, 283:195-200