Correlation of characteristics of gel extrusion module (GEM) tablet formulation and drug dissolution rate

Journal of Controlled Release

Volumn 89, Issue 3, 2003, Pages 375-385

  Juang, Rong Hwei ^a   Storey, David ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Carbopol polymers; Controlled release; DMA; GEM tablet; Neutralizing agent; Swelling

Indexed keywords

COMPACTION; COMPOSITION; DISSOLUTION; DRUG PRODUCTS; DYNAMIC MECHANICAL ANALYSIS; GRANULATION; POLYMERS; SWELLING; WATER;

TABLETS;

CONTROLLED DRUG DELIVERY;

CARBOMER; CARBOPOL 974P; DRUG; EXCIPIENT; POLYMER; POTASSIUM DIHYDROGEN PHOSPHATE; RESIN;

ANALYTIC METHOD; ARTICLE; CONTROLLED RELEASE FORMULATION; CORRELATION ANALYSIS; DRUG COATING; DRUG GRANULATION; DRUG SOLUBILITY; DRUG STABILITY; LASER; LINEAR SYSTEM; MEMBRANE PERMEABILITY; MEMBRANE TECHNOLOGY; PELLET EXTRUSION; PHARMACEUTICAL ENGINEERING; POROSITY; PRIORITY JOURNAL; PROCESS DEVELOPMENT; TABLET FORMULATION;

EID: 0038064313     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(03)00129-9     Document Type: Article

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