Homology modelling and docking studies on Varicella Zoster Virus Thymidine kinase

European Journal of Medicinal Chemistry

Volumn 38, Issue 4, 2003, Pages 413-419

  Spadola, Loredana ^a,b   Novellino, Ettore ^a   Folkers, Gerd ^b   Scapozza, Leonardo ^b  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b ETH ZURICH   (Switzerland)

Author keywords

Antiviral therapy; Homology modelling; Molecular docking; Varicella Zoster

Indexed keywords

5 (2 BROMOVINYL) 2' DEOXYURIDINE; ACICLOVIR; GANCICLOVIR; THYMIDINE; THYMIDINE KINASE; VIRUS ENZYME;

COMPUTER MODEL; COMPUTER PROGRAM; CONFERENCE PAPER; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ENZYME SUBSTRATE; HERPES SIMPLEX VIRUS 1; MOLECULAR MODEL; STRUCTURAL HOMOLOGY; VARICELLA ZOSTER VIRUS;

EID: 0038054838     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(03)00053-9     Document Type: Conference Paper

References (35)

1. Arvin A. Fields P., Knipe D., Howley P. Varicella Zoster Virus in Fields Virology. 1995;2547-2586 Raven, New York.
2. Cohen J., Straus S. Fields P., Knipe D., Howley P. Varicella Zoster Virus and Its Replication in Fields Virology. 1995;2525-2546 Raven, New York.
3. McGeoch D.J., Cook S., Dolan A., Jamieson F.E., Telford E.A.R. J. Mol. Biol. 247:1995;443-458.
4. Roizman B., Sears A.E. Fields P., Knipe D., Howley P. Herpes Simplex Viruses and Their Replication in Fields Virology. 1995;Raven, New York.
5. Cohen P.R., Beltrani V.P., Grossman M.E. Am. J. Med. 84:1988;1076-1080.
6. Schimpff S., Serpick A., Stoler B., Rumack B., Mellin H., Joseph J.M., Block J. Ann. Int. Med. 76:1972;241-254.
7. Taylor C.E., Sviland L., Pearson A.D., Dobb M., Reid M.W., Kernahan J., Craft A.W., Hamilton P.J., Proctor S. J. Clin. Pathol. 43:1990;633-637.
8. Culver K.W., Ram Z., Wallbridge S., Ishii H., Oldfield E.H., Blaese R.M. Science. 256:1992;1550-1552.
9. Bonini C., Ferrari G., Verzeletti S., Servida P., Zappone E., Ruggieri L., Ponzoni M., Rossini S., Mavilio F., Traversari C., Bordignon C. Science. 276:1997;1719-1724.
10. Chen M.S., Prusoff W.H. J. Biol. Chem. 253:1978;1325-1327.
11. Chen M.S., Walker J., Prusoff W.H. J. Biol. Chem. 254:1979;10747-10753.
12. Waldman A.S., Haeusslein E., Milman G. J. Biol. Chem. 258:1983;11571-11575.
13. Keller P.M., Fyfe J.A., Beauchamp L., Lubbers C.M., Furman P.A., Schaeffer H.J., Elion G.B. Biochem. Pharmacol. 30:1981;3071-3077.
14. Larder B.A., Cheng Y.C., Darby G. J. Gen. Virol. 64:1983;523-532.
15. Smee D.F., Martin J.C., Verheyden J.P., Matthews T.R. Antimicrob. Agents Chemother. 23:1983;676-682.
16. Pilger B.D., Perozzo R., Alber F., Wurth C., Folkers G., Scapozza L. J. Biol. Chem. 274:1999;31967-31973.
17. Prota A., Vogt J., Perozzo R., Pilger B.D., Wurth C., Marquez V., Russ P., Schulz G., Folkers G., Scapozza L. Biochemistry. 39:2000;9597-9603.
18. Amrhein I., Wurth C., Bohner T., Hofbauer R., Folkers G., Scapozza L. Protein Expres. Purif. 18:2000;338-345.
19. Bennett M.S., Wien F., Champness J.N., Batuwangala T., Rutherford T., Summers W.C., Sun H., Wright G., Sanderson M.R. FEBS Lett. 443:1999;121-125.
20. Brown D.G., Visse R., Sandhu G., Davies A., Rizkallah P.J., Melitz C., Summers W.C., Sanderson M.R. Nat. Struct. Biol. 2:1995;876-881.
21. Champness J.N., Bennett M.S., Wien F., Visse R., Summers W.C., Herdewijn P., de Clerq E., Ostrowski T., Jarvest R.L., Sanderson M.R. Proteins. 32:1998;350-361.
22. Wild K., Bohner T., Aubry A., Folkers G., Schulz G.E. FEBS Lett. 368:1995;289-292.
23. Wild K., Bohner T., Folkers G., Schulz G.E. Protein Sci. 6:1997;2097-2106.
24. Person W.R., Wood T., Zhang Z., Miller W. Genomics. 46:1997;24-36.
25. SYBYL, TRIPOS Inc., St. Louis, Missouri.
26. Laskowski R.A., McArthur M.W., Moos D.S., Thornton J.M.J. Appl. Cryst. 26:1993;283-291.
27. AMBER 5, University of California, San Francisco.
28. Ryckaert J.-P., Ciccotti G., Berendsen H.G.C. J. Comput. Phys. 23:1977;327-341.
29. Morris G.M., Goodsell D.S., Halliday R.S., Huey R., Hart W.E., Belew R.K., Olson A.J. J. Comput. Chem. 19:1998;1639-1662.
30. P. Pospisil, L. Scapozza, G. Folkers, Proceedings of the 13th European Symposium on QSAR-Rational Approaches in Drug Design, 2001, pp. 92-96.
31. Gasteiger J., Marsili M. Tetrahedron. 36:1980;3219-3228.
32. Alber F., Kuonen O., Scapozza L., Folkers G., Carloni P. Proteins: Struct. Funct. Genet. 31:1998;453-459.
33. Sienaert R., Naesens L., Brancale A., de Clerq E., McGuigan C., Balzarini J. Mol. Pharmacol. 61:2002;249-254.
34. Suzutani T., Davies L.C., Honess R.W. J Gen. Virol. 74:1993;1011-1016.
35. Sulpizi M., Schelling P., Folkers G., Carloni P., Scapozza L. J. Biol. Chem. 276:2001;21692-21697.