-
1
-
-
0028835235
-
+ channel revealed by the NMR-derived structures of scorpion toxins
-
+ channel revealed by the NMR-derived structures of scorpion toxins. Neuron, 15, 1169-1181.
-
(1995)
Neuron
, vol.15
, pp. 1169-1181
-
-
Aiyar, J.1
Withka, J.M.2
Rizzi, J.P.3
Singleton, D.H.4
Andrews, G.C.5
Lin, W.6
Boyd, J.7
Hanson, D.C.8
Simon, M.9
Dethlefs, B.10
-
3
-
-
0028124225
-
Episodic ataxia/myokymia syndrome is associated with point mutations in the human potassium channel gene, KCNA1
-
Browne, D.L., Gancher, S.T., Nutt, J.G., Brunt, E.R., Smith, E.A., Kramer, P. & Litt, M. (1994) Episodic ataxia/myokymia syndrome is associated with point mutations in the human potassium channel gene, KCNA1. Nature Genet., 8, 136-140.
-
(1994)
Nature Genet.
, vol.8
, pp. 136-140
-
-
Browne, D.L.1
Gancher, S.T.2
Nutt, J.G.3
Brunt, E.R.4
Smith, E.A.5
Kramer, P.6
Litt, M.7
-
4
-
-
0030720015
-
Ion channels in the immune system as targets for immunosuppression
-
Cahalan, M.D. & Chandy, K.G. (1997) Ion channels in the immune system as targets for immunosuppression. Curr. Opin. Biotechnol., 8, 749-756.
-
(1997)
Curr. Opin. Biotechnol.
, vol.8
, pp. 749-756
-
-
Cahalan, M.D.1
Chandy, K.G.2
-
5
-
-
0029026638
-
Structure and function of voltage-gated ion channels
-
Catterall, W.A. (1995) Structure and function of voltage-gated ion channels. Annu. Rev. Biochem., 64, 493-531.
-
(1995)
Annu. Rev. Biochem.
, vol.64
, pp. 493-531
-
-
Catterall, W.A.1
-
6
-
-
6544276937
-
On the convergent evolution of animal toxins. Conservation of a diad of functional residues in potassium channel-blocking toxins with unrelated structures
-
Dauplais, M., Lecoq, A., Song, J., Cotton, J., Jamin, N., Gilquin, B., Roumestand, C., Vita, C., de Medeiros, C.L., Rowan, E.G., Harvey, A.L. & Menez, A. (1997) On the convergent evolution of animal toxins. Conservation of a diad of functional residues in potassium channel-blocking toxins with unrelated structures. J. Biol. Chem., 272, 4302-4309.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 4302-4309
-
-
Dauplais, M.1
Lecoq, A.2
Song, J.3
Cotton, J.4
Jamin, N.5
Gilquin, B.6
Roumestand, C.7
Vita, C.8
De Medeiros, C.L.9
Rowan, E.G.10
Harvey, A.L.11
Menez, A.12
-
8
-
-
0027219545
-
Influence of protein surface charge on the himolecular kinetics of a potassium channel peptide inhibitor
-
Escobar, L., Root, M.J. & MacKinnon, R. (1993) Influence of protein surface charge on the himolecular kinetics of a potassium channel peptide inhibitor. Biochemistry., 32, 6982-6987.
-
(1993)
Biochemistry
, vol.32
, pp. 6982-6987
-
-
Escobar, L.1
Root, M.J.2
MacKinnon, R.3
-
10
-
-
15644375485
-
Delineation of the functional site of alpha-dendrotoxin. The functional topographies of dendrotoxins are different but share a conserved core with those of other Kv1 potassium channel-blocking toxins
-
Gasparini, S., Danse, J.M., Lecoq, A., Pinkasfeld, S., Zinn-Justin, S., Young, L.C., de Medeiros, C.C., Rowan, E.G., Harvey, A.L. & Menez, A. (1998) Delineation of the functional site of alpha-dendrotoxin. The functional topographies of dendrotoxins are different but share a conserved core with those of other Kv1 potassium channel-blocking toxins. J. Biol. Chem., 273, 25393-25403.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 25393-25403
-
-
Gasparini, S.1
Danse, J.M.2
Lecoq, A.3
Pinkasfeld, S.4
Zinn-Justin, S.5
Young, L.C.6
De Medeiros, C.C.7
Rowan, E.G.8
Harvey, A.L.9
Menez, A.10
-
12
-
-
0028276482
-
+ channel: Peptide and channel residues mediating molecular recognition
-
+ channel: peptide and channel residues mediating molecular recognition. Neuron, 12, 1377-1388.
-
(1994)
Neuron
, vol.12
, pp. 1377-1388
-
-
Goldstein, S.A.1
Pheasant, D.J.2
Miller, C.3
-
13
-
-
85047696278
-
Purification, characterization and biosynthesis of parabutoxin 3, a component of Parabuthus transvaalicus venom
-
Huys, I., Dyason, K., Waelkens, E., Verdonck, F., van Zyl, J., du Plessis, J., Muller, G.J., van der Walt, J., Clynen, E., Schoofs, L. & Tytgat, J. (2002) Purification, characterization and biosynthesis of parabutoxin 3, a component of Parabuthus transvaalicus venom. Eur. J. Biochem., 269, 1854-1865.
-
(2002)
Eur. J. Biochem.
, vol.269
, pp. 1854-1865
-
-
Huys, I.1
Dyason, K.2
Waelkens, E.3
Verdonck, F.4
Van Zyl, J.5
Du Plessis, J.6
Muller, G.J.7
Van Der Walt, J.8
Clynen, E.9
Schoofs, L.10
Tytgat, J.11
-
14
-
-
0028567150
-
The kaliotoxin family enlarged. Purification, characterization, and precursor nucleotide sequence of KTX2 from Androctonus australis venom
-
Laraba-Djebari, F., Legros, C., Crest, M., Ceard, B., Romi, R., Mansuelle, P., Jacquet, G., van Rietschoten, J., Gola, M. & Rochat, H. (1994) The kaliotoxin family enlarged. Purification, characterization, and precursor nucleotide sequence of KTX2 from Androctonus australis venom. J. Biol. Chem., 269, 32835-32843.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 32835-32843
-
-
Laraba-Djebari, F.1
Legros, C.2
Crest, M.3
Ceard, B.4
Romi, R.5
Mansuelle, P.6
Jacquet, G.7
Van Rietschoten, J.8
Gola, M.9
Rochat, H.10
-
15
-
-
0029012475
-
Pore loops: An emerging theme in ion channel structure
-
MacKinnon, R. (1995) Pore loops: an emerging theme in ion channel structure. Neuron, 14, 889-892.
-
(1995)
Neuron
, vol.14
, pp. 889-892
-
-
MacKinnon, R.1
-
16
-
-
0024426645
-
Mutant potassium channels with altered binding of charybdotoxin, a pore-blocking peptide inhibitor
-
MacKinnon, R. & Miller, C. (1989) Mutant potassium channels with altered binding of charybdotoxin, a pore-blocking peptide inhibitor. Science, 245, 1382-1385.
-
(1989)
Science
, vol.245
, pp. 1382-1385
-
-
MacKinnon, R.1
Miller, C.2
-
17
-
-
0025299296
-
Diffusion-controlled binding of a peptide neurotoxin to its K+ channel receptor
-
Miller, C. (1990) Diffusion-controlled binding of a peptide neurotoxin to its K+ channel receptor. Biochemistry, 29, 5320-5325.
-
(1990)
Biochemistry
, vol.29
, pp. 5320-5325
-
-
Miller, C.1
-
18
-
-
0028983387
-
The charybdotoxin family of K+ channel-blocking peptides
-
Miller, C. (1995) The charybdotoxin family of K+ channel-blocking peptides. Neuron, 15, 5-10.
-
(1995)
Neuron
, vol.15
, pp. 5-10
-
-
Miller, C.1
-
19
-
-
0030044863
-
A strongly interacting pair of residues on the contact surface of charybdotoxin and a Shaker K+ channel
-
Naranjo, D. & Miller, C. (1996) A strongly interacting pair of residues on the contact surface of charybdotoxin and a Shaker K+ channel. Neuron, 16, 123-130.
-
(1996)
Neuron
, vol.16
, pp. 123-130
-
-
Naranjo, D.1
Miller, C.2
-
21
-
-
0026666693
-
Mapping function to structure in a channel-blocking peptide: Electrostatic mutants of charybdotoxin
-
Park, C.S. & Miller, C. (1992) Mapping function to structure in a channel-blocking peptide: electrostatic mutants of charybdotoxin. Biochemistry, 31, 7749-7755.
-
(1992)
Biochemistry
, vol.31
, pp. 7749-7755
-
-
Park, C.S.1
Miller, C.2
-
22
-
-
0030064382
-
+ channel selectivity filter by mutant cycle-based structure analysis
-
+ channel selectivity filter by mutant cycle-based structure analysis. Neuron, 16, 131-139.
-
(1996)
Neuron
, vol.16
, pp. 131-139
-
-
Ranganathan, R.1
Lewis, J.H.2
MacKinnon, R.3
-
24
-
-
0032554613
-
Three-dimensional structure of kappa-conotoxin PVIIA, a novel potassium channel-blocking toxin from cone snails
-
Savarin, P., Guenneugues, M., Gilquin, B., Lamthanh, H., Gasparini, S., ZinnJustin, S. & Menez, A. (1998) Three-dimensional structure of kappa-conotoxin PVIIA, a novel potassium channel-blocking toxin from cone snails. Biochemistry, 37, 5407-5416.
-
(1998)
Biochemistry
, vol.37
, pp. 5407-5416
-
-
Savarin, P.1
Guenneugues, M.2
Gilquin, B.3
Lamthanh, H.4
Gasparini, S.5
ZinnJustin, S.6
Menez, A.7
-
27
-
-
19044384234
-
Kappa-Hefutoxin1, a novel toxin from the scorpion Heterometrus fulvipes with unique structure and function: Importance of the functional diad in potassium channel selectivity
-
Srinivasan, K.N., Sivaraja, V., Huys, I., Sasaki, T., Cheng, B., Kumar, T.K., Sato, K. & Tytgat, J., Yu, C., Brian Chia, C.S., Ranganathan, S., Bowie, J.H., Kini, R.M. & Gopalakrishnakone, P. (2002) kappa-Hefutoxin1, a novel toxin from the scorpion Heterometrus fulvipes with unique structure and function: Importance of the functional diad in potassium channel selectivity. J. Biol. Chem., 277, 30040-30047.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 30040-30047
-
-
Srinivasan, K.N.1
Sivaraja, V.2
Huys, I.3
Sasaki, T.4
Cheng, B.5
Kumar, T.K.6
Sato, K.7
Tytgat, J.8
Yu, C.9
Brian Chia, C.S.10
Ranganathan, S.11
Bowie, J.H.12
Kini, R.M.13
Gopalakrishnakone, P.14
-
28
-
-
0028117321
-
+ channel structure from a complete functional map of the molecular surface of charybdotoxin
-
+ channel structure from a complete functional map of the molecular surface of charybdotoxin. Biochemistry, 33, 443-450.
-
(1994)
Biochemistry
, vol.33
, pp. 443-450
-
-
Stampe, P.1
Kolmakova-Partensky, L.2
Miller, C.3
-
29
-
-
0032753963
-
A unified nomenclature for short-chain peptides isolated from scorpion venoms: Alpha-KTx molecular subfamilies
-
Tytgat, J., Chandy, K.G., Garcia, M.L., Gutman, G.A., Martin-Eauclaire, M.F., van der Walt, J.J. & Possani, L.D. (1999) A unified nomenclature for short-chain peptides isolated from scorpion venoms: alpha-KTx molecular subfamilies. Trends Pharmacol. Sci., 20, 444-447.
-
(1999)
Trends Pharmacol. Sci.
, vol.20
, pp. 444-447
-
-
Tytgat, J.1
Chandy, K.G.2
Garcia, M.L.3
Gutman, G.A.4
Martin-Eauclaire, M.F.5
Van Der Walt, J.J.6
Possani, L.D.7
|