Applications of parallel synthesis to lead optimization

Chimia

Volumn 57, Issue 5, 2003, Pages 262-269

  Altorfer, Michael ^a   Ermert, Philipp ^a   Fässler, Jürg ^a   Farooq, Saleem ^b   Hillesheim, Elke ^b   Jeanguenat, André ^b   Klumpp, Klaus ^c   Maienfisch, Peter ^b   Martin, Joseph A ^c   Merrett, John H ^c   Parkes, Kevin E B ^c   Obrecht, Jean Pierre ^a   Pitterna, Thomas ^b   Obrecht, Daniel ^a  

^a Polyphor Ltd   (Switzerland)

^b SYNGENTA CROP PROTECTION AG   (Switzerland)

^c ROCHE PRODUCTS LTD   (United Kingdom)

Author keywords

High throughput purification; Insecticidal and fungicidal thiazoles; Insecticidal triazines; Lead validation and optimization; N hydroxy indolin 2 ones as influenza endonuclease inhibitors; Parallel synthesis

Indexed keywords

ENDONUCLEASE INHIBITOR; ENZYME INHIBITOR; FUNGICIDE; INSECTICIDE; THIAZOLE DERIVATIVE; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; COMBINATORIAL CHEMISTRY; COMBINATORIAL LIBRARY; DRUG DESIGN; DRUG MECHANISM; DRUG SYNTHESIS; FUNGICIDAL ACTIVITY; HERBICIDAL ACTIVITY; INSECTICIDAL ACTIVITY; PURIFICATION; SYNTHESIS;

EID: 0038043147     PISSN: 00094293     EISSN: None     Source Type: Journal    
DOI: 10.2533/000942903777679271     Document Type: Article

References (12)

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