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Volumn 51, Issue 5, 2003, Pages 407-414

Ketotifen reverses MDR1-mediated multidrug resistance in human breast cancer cells in vitro and alleviates cardiotoxicity induced by doxorubicin in vivo

Author keywords

Cardiotoxicity; Doxorubicin; Ketotifen; Multidrug resistance (MDR)

Indexed keywords

CAMPTOTHECIN; DEXVERAPAMIL; DOXORUBICIN; ELACRIDAR; ETOPOSIDE; GLYCOPROTEIN P; KETOTIFEN; METHOTREXATE; VALSPODAR; VERAPAMIL; VINBLASTINE;

EID: 0038018602     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-003-0600-5     Document Type: Article
Times cited : (24)

References (31)
  • 1
    • 0033836109 scopus 로고    scopus 로고
    • Can multidrug resistance mechanisms be modified?
    • Arceci RJ (2000) Can multidrug resistance mechanisms be modified? Br J Haematol 110:285
    • (2000) Br J Haematol , vol.110 , pp. 285
    • Arceci, R.J.1
  • 4
    • 0034210816 scopus 로고    scopus 로고
    • Anthracyclines and cardiotoxicity
    • Birtle AJ (2000) Anthracyclines and cardiotoxicity. Clin Oncol 12:146
    • (2000) Clin Oncol , vol.12 , pp. 146
    • Birtle, A.J.1
  • 5
    • 0030921949 scopus 로고    scopus 로고
    • ICRF-187 as a cardioprotectant in children treated with anthracyclines
    • Blatt J (1997) ICRF-187 as a cardioprotectant in children treated with anthracyclines. Pediatr Hematol Oncol 14:iii
    • (1997) Pediatr Hematol Oncol , vol.14
    • Blatt, J.1
  • 6
    • 0032211417 scopus 로고    scopus 로고
    • Multidrug resistance mediated by the ATP-binding cassette transporter protein MRP
    • Cole SP, Deeley RG (1998) Multidrug resistance mediated by the ATP-binding cassette transporter protein MRP. Bioessays 20:931
    • (1998) Bioessays , vol.20 , pp. 931
    • Cole, S.P.1    Deeley, R.G.2
  • 7
    • 0028816350 scopus 로고
    • A phase III randomized study of oral verapamil as a chemosensitizer to reverse drug resistance in patients with refractory myeloma
    • A Southwest Oncology Group study
    • Dalton WS, Crowley JJ, Salmon SS, Grogan TM, Laufman LR, Weiss GR, Bonnet JD (1995) A phase III randomized study of oral verapamil as a chemosensitizer to reverse drug resistance in patients with refractory myeloma. A Southwest Oncology Group study. Cancer 75:815
    • (1995) Cancer , vol.75 , pp. 815
    • Dalton, W.S.1    Crowley, J.J.2    Salmon, S.S.3    Grogan, T.M.4    Laufman, L.R.5    Weiss, G.R.6    Bonnet, J.D.7
  • 9
    • 0029784750 scopus 로고    scopus 로고
    • Cytoprotective agents for anthracyclines
    • Dorr RT (1996) Cytoprotective agents for anthracyclines. Semin Oncol 23:23
    • (1996) Semin Oncol , vol.23 , pp. 23
    • Dorr, R.T.1
  • 10
    • 0028935166 scopus 로고
    • Modulators of multidrug resistance. Preclinical studies
    • Ford JM (1995) Modulators of multidrug resistance. Preclinical studies. Hematol Oncol Clin North Am 9:337
    • (1995) Hematol Oncol Clin North Am , vol.9 , pp. 337
    • Ford, J.M.1
  • 11
    • 0027940433 scopus 로고
    • Non-specific effects of calcium entry antagonists in mast cells
    • Franzius D, Hoth M, Penner R (1994) Non-specific effects of calcium entry antagonists in mast cells. Pflugers Arch 428:433
    • (1994) Pflugers Arch , vol.428 , pp. 433
    • Franzius, D.1    Hoth, M.2    Penner, R.3
  • 12
    • 0033006172 scopus 로고    scopus 로고
    • A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin
    • Gewirtz DA (1999) A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. Biochem Pharmacol 57:727
    • (1999) Biochem Pharmacol , vol.57 , pp. 727
    • Gewirtz, D.A.1
  • 14
    • 0032520979 scopus 로고    scopus 로고
    • Protection from apoptosis by steel factor but not interleukin-3 is reversed through blockade of calcium influx
    • Gommerman JL, Berger SA (1998) Protection from apoptosis by steel factor but not interleukin-3 is reversed through blockade of calcium influx. Blood 91:1891
    • (1998) Blood , vol.91 , pp. 1891
    • Gommerman, J.L.1    Berger, S.A.2
  • 15
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman MM, Pastan I (1993) Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 62:385
    • (1993) Annu Rev Biochem , vol.62 , pp. 385
    • Gottesman, M.M.1    Pastan, I.2
  • 16
    • 0033813886 scopus 로고    scopus 로고
    • Molecular basis of anthracycline-induced cardiotoxicity and its prevention
    • Horenstein MS, Vander Heide RS, L'Ecuyer TJ (2000) Molecular basis of anthracycline-induced cardiotoxicity and its prevention. Mol Genet Metab 71:436
    • (2000) Mol Genet Metab , vol.71 , pp. 436
    • Horenstein, M.S.1    Vander Heide, R.S.2    L'Ecuyer, T.J.3
  • 17
    • 0031837125 scopus 로고    scopus 로고
    • Chemotherapy resistance in breast cancer
    • Lehnert M (1998) Chemotherapy resistance in breast cancer. Anticancer Res 18:2225
    • (1998) Anticancer Res , vol.18 , pp. 2225
    • Lehnert, M.1
  • 18
    • 0030738677 scopus 로고    scopus 로고
    • Multidrug resistance: Molecular mechanisms and clinical relevance
    • Ling V (1997) Multidrug resistance: molecular mechanisms and clinical relevance. Cancer Chemother Pharmacol 40:S3
    • (1997) Cancer Chemother Pharmacol , vol.40
    • Ling, V.1
  • 19
    • 0027455027 scopus 로고
    • Randomized phase II study of single-agent epirubicin ± verapamil in patients with advanced metastatic breast cancer. An AIO clinical trial
    • Arbeitsgemeinschaft Internistische Onkologie of the German Cancer Society
    • Mross K, Bohn C, Edler L, Jonat W, Queisser W, Heidemann E, Goebel M, Hossfeld DK (1993) Randomized phase II study of single-agent epirubicin ± verapamil in patients with advanced metastatic breast cancer. An AIO clinical trial. Arbeitsgemeinschaft Internistische Onkologie of the German Cancer Society. Ann Oncol 4:45
    • (1993) Ann Oncol , vol.4 , pp. 45
    • Mross, K.1    Bohn, C.2    Edler, L.3    Jonat, W.4    Queisser, W.5    Heidemann, E.6    Goebel, M.7    Hossfeld, D.K.8
  • 22
    • 0028009810 scopus 로고
    • Multidrug resistance-associated protein gene overexpression and reduced drug sensitivity of topoisomerase II in a human breast carcinoma MCF7 cell line selected for etoposide resistance
    • Schneider E, Horton JK, Yang CH, Nakagawa M, Cowan KH (1994) Multidrug resistance-associated protein gene overexpression and reduced drug sensitivity of topoisomerase II in a human breast carcinoma MCF7 cell line selected for etoposide resistance. Cancer Res 54:152
    • (1994) Cancer Res , vol.54 , pp. 152
    • Schneider, E.1    Horton, J.K.2    Yang, C.H.3    Nakagawa, M.4    Cowan, K.H.5
  • 24
    • 0037133929 scopus 로고    scopus 로고
    • 2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells
    • 2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. J Biol Chem 277:13812
    • (2002) J Biol Chem , vol.277 , pp. 13812
    • Soboloff, J.1    Berger, S.A.2
  • 25
    • 0036791037 scopus 로고    scopus 로고
    • Sensitivity of myeloid leukemia cells to calcium influx blockade: Application to bone marrow purging
    • Soboloff J, Zhang Y, Minden M, Berger SA (2002) Sensitivity of myeloid leukemia cells to calcium influx blockade: application to bone marrow purging. Exp Hematol 30:1219
    • (2002) Exp Hematol , vol.30 , pp. 1219
    • Soboloff, J.1    Zhang, Y.2    Minden, M.3    Berger, S.A.4
  • 26
    • 0005468060 scopus 로고    scopus 로고
    • Valspodar + paclitaxel in advanced breast cancer: A California Cancer Consortium phase II randomized trial
    • abstract 696
    • Spicer D, Arzoo K, Groshen S, et al (2000) Valspodar + paclitaxel in advanced breast cancer: a California Cancer Consortium phase II randomized trial (abstract 696). Proc ASCO 19:179a
    • (2000) Proc ASCO , vol.19
    • Spicer, D.1    Arzoo, K.2    Groshen, S.3
  • 28
    • 0034456656 scopus 로고    scopus 로고
    • Multidrug resistance transporters and modulation
    • Tan B, Piwnica-Worms D, Ratner L (2000) Multidrug resistance transporters and modulation. Curr Opin Oncol 12:450
    • (2000) Curr Opin Oncol , vol.12 , pp. 450
    • Tan, B.1    Piwnica-Worms, D.2    Ratner, L.3
  • 29
    • 0030920342 scopus 로고    scopus 로고
    • Multidrug resistance in breast cancer: A meta-analysis of MDR1/gp170 expression and its possible functional significance
    • Trock BJ, Leonessa F, Clarke R (1997) Multidrug resistance in breast cancer: a meta-analysis of MDR1/gp170 expression and its possible functional significance. J Natl Cancer Inst 89:917
    • (1997) J Natl Cancer Inst , vol.89 , pp. 917
    • Trock, B.J.1    Leonessa, F.2    Clarke, R.3
  • 30
    • 0008632564 scopus 로고
    • Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine
    • Ueda K, Cardarelli C, Gottesman MM, Pastan I (1987) Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine. Proc Natl Acad Sci U S A 84:3004
    • (1987) Proc Natl Acad Sci U S A , vol.84 , pp. 3004
    • Ueda, K.1    Cardarelli, C.2    Gottesman, M.M.3    Pastan, I.4
  • 31
    • 0036010918 scopus 로고    scopus 로고
    • Purging of contaminating breast cancer cells from hematopoietic progenitor cell preparations using activation enhanced cell death
    • Zhang Y, Crump M, Berger SA (2002) Purging of contaminating breast cancer cells from hematopoietic progenitor cell preparations using activation enhanced cell death. Breast Cancer Res Treat 72:265
    • (2002) Breast Cancer Res Treat , vol.72 , pp. 265
    • Zhang, Y.1    Crump, M.2    Berger, S.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.