Acetylcholinesterase inhibitors from the roots of Angelica dahurica

Archives of Pharmacal Research

Volumn 25, Issue 6, 2002, Pages 856-859

  Dae, Keun Kim ^a   Jong, Pil Lim ^a   Jae, Heon Yang ^a   Dong, Ok Eom ^a   Jae, Soon Eun ^a   Kang, Hyun Leem ^a  

^a Woosuk University   (South Korea)

Author keywords

Angelica dahurica; Anticholinesterase activity; Imperatorin; Isoimperatorin; Oxypeucedanin

Indexed keywords

ACETYLCHOLINESTERASE; CHOLINESTERASE INHIBITOR; PLANT EXTRACT;

ANGELICA; ANIMAL; ARTICLE; BRAIN; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; ISOLATION AND PURIFICATION; METABOLISM; MOUSE; PLANT ROOT;

ACETYLCHOLINESTERASE; ANGELICA; ANIMALS; BRAIN; CHOLINESTERASE INHIBITORS; MICE; PLANT EXTRACTS; PLANT ROOTS;

EID: 0038003872     PISSN: 02536269     EISSN: 02536269     Source Type: Journal    
DOI: 10.1007/bf02977004     Document Type: Article

References (19)

1. Bartus, R. T., On neurodegenerative diseases, models, and treatment strategies: lessons learned and lessons forgotten a generation following the cholinergic hypothesis. Exp. Neurol., 163, 495-529 (2000).
2. Bartus, R. T., Dean, R. L., Beer, B., and Lippa, A. S., The cholinergic hypothesis of geriatric memory dysfunction. Science, 217, 408-414 (1982).
3. Baek, N. I., Ahn, E. M., Kim H. Y., and Park, Y. D., Furanocoumarins from the root of Angelica dahurica. Arch. Pharm. Res., 23, 467-470 (2000).
4. Broadwell, R. D., and Sofroniew, M. V., Serum proteins bypass the blood-brain fluid barriers for extracellular entry to the central nervous system. Exp. Neurol. 120, 245-263 (1993).
5. Cho, J. Y., Lee, J. S., Park, J. S., and Park, M. H., Isolation of inhibitory componints on tumor necrosis factor- produttion from Angelica koreana. Yakhak Hoeji, 42, 125-131 (1998).
6. Chung, Y. K., Heo, H. J., Kim, E. K., Kim, H. K., Huh, T. L, Lim, Y., Kim, S. K., and Shin, D. H., Inhibitory effect of ursolic acid purified from Origanum majorana L. on the acetylcholinesterse. Mol. Cells, 11, 137-143 (2001).
7. Ellman, G. L., Courtney, D., Valentino, A., and Featherstone, R. M., A new and rapid colorimetric determination of acetyl-cholinesterase activity. Biochem. Pharmacol., 7, 88-95 (1961).
8. Hwang, S. Y., Chang, Y. P., Byun, S. J., Jeon, M. H., and Kim, Y, C., An acetylcholinesterase inhibitor isolated from Corydalis Tuber and its mode of action. Kor. J. Pharmacogn., 27, 91-95 (1996).
9. Kim, S. H., Kang, S. S., and Kim, C. M., Coumarin glycosides from the roots of Angelica dahurica. Arch. Pharm. Res., 15, 73-77 (1992).
10. Kimura, T,, But, P. P. H., Guo, J. X., and Sung, C. K., International collation of traditional and folk medicine: Part 1. World scientific, Singapore, pp. 117-118, (1996).
11. Kwon, Y. S., Shin, S. J., Kim M. J., and Kim, C. M., A new coumarin from the stem of Angelica dahurica. Arch. Pharm. Res., 25, 53-56 (2002).
12. Kwon, Y. S., Woo, E. R., and Kim, C. M., A study on the constituents of bioactive fractions of Ostericum koreanum Kitagawa. Kor. J. Pharmacogn. 22, 156-161 (1991).
13. Park, C. H., Kim, S. H., Choi, W., Lee, Y. J., Kim, J. S., Kang, S. S., and Suh, Y. H., Novel anticholinesterase and antiamnesic activities of dehydroevodiamine, a constituent of Evodia rutaecarpa. Planta Med. 62, 405-409 (1996).
14. Perry, E. K., The cholinergic hypothesis - Ten years on. Br. Med. Bull., 42, 63-69 (1986).
15. Qiao, S. Y., Qao, X. S., and Wang, Z. Y., Coumarins of the roots of Angelica dahurica. Planta Med., 62, 584 (1996).
16. Rhee, I. K., van de Meent, M., Ingkaninan, K., and Verpoorte, R., Screening for acetylcholinesterase inhibitors from Amaryllidaceae using silica gel thin-layer chromatography in combination with bioactivity staining. J. Chromatogr. A, 915, 217-223 (2001).
17. Riger, F., Shelanski, M. L., and Greene, L. A., The effects of nerve growh factor on acetylcholinesterase and its multiple forms in cultures of rat PC12 pheochromocytoma cells; increased total specific activity and appearance of the 16 S molecular form. Dev. Biol. 76, 238-243 (1980).
18. Wang, N. H., Yoshiazaki, K., and Baba, K., Seven new bifuranocoumarins, dahuribirin A-G, from Japanese Bai Zhi. Chem. Pharm. Bull., 49, 1085-1088 (2001).
19. Woo, W. S., Lee, C. K., and Shin, K. H., Isolation of drug metabolism modifiers from roots of Angelica koreana. Planta Med. 45, 234-236 (1982).