Discovery of potent peptide-mimetic antagonists for the human thrombin receptor, protease-activated receptor-1 (PAR-1).

Current medicinal chemistry. Cardiovascular and hematological agents

Volumn 1, Issue 1, 2003, Pages 13-36

  Maryanoff, Bruce E ^a   Zhang, Han Cheng ^a   Andrade Gordon, Patricia ^a   Derian, Claudia K ^a  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITHROMBOCYTIC AGENT; HETEROCYCLIC COMPOUND; PEPTIDE; PROTEINASE ACTIVATED RECEPTOR 1;

ANIMAL; CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; DRUG EFFECT; HUMAN; IC 50; MOLECULAR MIMICRY; REVIEW; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; SYNTHESIS; THROMBOSIS;

ANIMALS; DRUG DESIGN; HETEROCYCLIC COMPOUNDS; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR MIMICRY; PEPTIDES; PLATELET AGGREGATION INHIBITORS; RECEPTOR, PAR-1; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; THROMBOSIS;

EID: 0037995630     PISSN: 15680169     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568016033356724     Document Type: Review

References (44)